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Les effets pharmacologiques d’extraits d’Epilobium

Pharmacological effects of Epilobium extracts

  • Article Original
  • Pharmacognosie
  • Published:
Phytothérapie

Résumé

Depuis les premiers travaux montrant en 1988 qu’Epilobium parviflorum agissait sur le tissu prostatique en améliorant la symptomatologie de l’hypertrophie bénigne de la prostate, les études se sont faites rares. Après des travaux sur la prolifération du tissu prostatique, l’auteuir a voulu vérifié cet effet pour différentes épilobes, comme pour des épilobes d’origine géographique différente. Il semble que les plus actifs sont E. angustifolia et E. rosmarinifolia. Parmi les constituants chimiques il semble par ailleurs que ce soit avant tout l’oenothéine B qui est active, mais son activité n’explique pas toute l’activité du totum de la plante.

Abstract

Since the first studies in 1988 showing that Epilobium parviflorum affects prostate tissue by improving the symptoms of benign prostatic hypertrophy, other similar studies have been scarce. After studies on the proliferation of prostate tissue, the author wanted to verify this effect for different types of epilobium, such as those of different geographical origins. It would appear that the most active types are E. angustifolia and E. rosmarinifolia. Of all the chemical components, it would appear that oenothein B is primarily active, but its activity does not explain all the activity of the plant totum.

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Bibliographie

  1. Battinelli L., Tita B, Evandri MG, et al. (2001) Antimicrobial activity of Epilobium spp. extracts. Farmaco 56: 345–348

    Article  PubMed  CAS  Google Scholar 

  2. Ducrey B, Marston A, Gohring S, et al. (1997) Inhibition of 5 alpha-reductase and aromatase by the ellagitannins oenothein A and oenothein B from Epilobium species. Planta Med. 63: 111–114

    Article  PubMed  CAS  Google Scholar 

  3. Ducrey B, Wolfender JL, Marston A, et al. (1995). Analysis of flavonol glycosides of thirteen Epilobium species (Onagraceae) by LC-UV and thermospray LC-MS. Phytochem 38: 129–137

    Article  CAS  Google Scholar 

  4. Gavrieli Y, Sherman Y, Ben-Sasson SA (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119: 493–501

    Article  PubMed  CAS  Google Scholar 

  5. Guizzetti M, Costa P, Peters J, et al. (1996) Acetylcholine as a mitogen: muscarinic receptor-mediated proliferation of rat astrocytes and human astrocytoma cells. Eur J Pharmacol 297: 265–263

    Article  PubMed  CAS  Google Scholar 

  6. Juan H, Samets W, Hiermann A (1988) Anti-inflammatory effects of a substance extracted from Epilobium angustifolium. Agents and Actions. Inflam Research 23(1–2): 106–107

    CAS  Google Scholar 

  7. Lesuisse D, Berjonneau J, Parent B, Teutsch G (1996) Determination of oenothein B as the active 5-alpha-reductase-inhibiting principle of the folk medicine Epilobium parviflorum. J Nat Prod 59(5): 490–492

    Article  PubMed  CAS  Google Scholar 

  8. Rabinovitch PS, Kubbies M, Chen YC, et al. (1988) U-Hoechst flow cytometry: a unique tool for quantitative cell cycle analysis. Exp Cell Res 174: 309–318

    Article  PubMed  CAS  Google Scholar 

  9. Romijn JC, Verkoelen CF, Schroeder FH (1988) Application of the MTT assay to human prostate cancer cell lines in vitro: establishment of test conditions and assessment of hormone-stimulated growth and drug-induced cytostatic and cytotoxic effects. Prostate 12: 99–110

    Article  PubMed  CAS  Google Scholar 

  10. Slacanin I, Marston A, Hostettmann K (1991) Isolation and determination of flavonol glycosides from Epilobium species. J Chromatogr A. 557: 391–398

    Article  CAS  Google Scholar 

  11. Tita B, Abdel-Haq H, Vitalone A, Mazzanti G, et al. (2001) Analgesic properties of Epilobium angustifolium, evaluated by the hot plate test and the writhing test. Farmaco 56: 341–343

    Article  PubMed  CAS  Google Scholar 

  12. Toth BH, Balazs A, Vukics V, et al. (2006) Identification of Epilobium species and Willow herbs by HPLC Analysis of Flavonoids as Chemotaxonomic Markers. Chromatographia 63,Suppl 3

    Google Scholar 

  13. Treben M (1984) Gesundheit aus der apotheke gottes. Health through god’s pharmacy. III ed. Verlag Wilhelm Ennsthaler

  14. Vitalone A, Mc Coll J, Thome D, et al. (2003) Characterization of the effect of Epilobium extracts on human cell proliferation. Pharmacology 69(2): 79–87

    Article  PubMed  CAS  Google Scholar 

  15. Xia Z, Dickens M, Raingeaud J, et al. (1995) Opposing effects of ERK and JNK, MAP kinases on apoptosis. Science 270: 1326–1331

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Université de Rome, Sapienza, Italie

    M. Celeste

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  1. M. Celeste
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Correspondence to M. Celeste.

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Celeste, M. Les effets pharmacologiques d’extraits d’Epilobium . Phytothérapie 6, 150–152 (2008). https://doi.org/10.1007/s10298-008-0320-4

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  • DOI: https://doi.org/10.1007/s10298-008-0320-4

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