Skip to main content
Log in

La canneberge d’Amérique, propriétés et indications

The American cranberry, properties and therapeutic indications

  • Monographie Médicalisée
  • Published:
Phytothérapie

Résumé

Les cystites récidivantes génèrent chaque année en France un volume de plus de 3,5 millions de prescriptions d’antibiothérapie. Elles concernent une majorité de femmes. D’autres se seront traitées par automédication. Cette pathologie très invalidante est le plus souvent liée à une bactérie intestinale, Escherichia coli. Cette bactérie possède la particularité de rester accrochée à la muqueuse vésicale via des fimbriae fixés par des adhésines, ce qui explique les récidives. La canneberge d’Amérique (Vaccinium macrocarpon) prise au long cours représente un véritable traitement non pas de la crise de cystite, mais préventif des récidives. Elle contient en effet des molécules spécifiques anti-adhésines des fimbriae d’Escherichia coli et permet au bout de quelques mois l’éradication du germe et la guérison de la pathologie.

Abstract

Every year in France, over 3.5 million prescriptions for antibiotics are for recurring cystitis (which affects mostly women). Others will turn to self-treatment. This pathology causes serious discomfort and is usually caused by a bowel bacterium, Escherichia coli. The bacterium can adhere to the bladder wall by means of fimbrial adhesins, thus explaining recurring bouts. American Cranberry (Vaccinium macrocarpon), taken over a long period of time, is an effective treatment, not for the individual bout of cystitis but to prevent recurrence. The plant contains specific molecules with an anti-Escherichia coli fimbrial adhesins effect. A few months of treatment will lead to the eradication of the germ, thus avoiding further relapse.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Bibliographie

  1. Afssa (2004) Avis du 6 avril, saisine no 2003-SA-0352

  2. Anonyme (2008) Cystites récidivantes, prévention par les PAC et L. Rhamnosus. 37°2 le Magazine 7 78: 26–30

  3. Aston JL, Lodolce AE, Shapiro NL (2006) Interaction between warfarin and cranberry juice. Pharmacotherapy 26(9): 1314–1319

    Article  PubMed  CAS  Google Scholar 

  4. Avorn J, Monane M, Gurwitz JH, et al. (1994) Reduction of bacteriuria and pyuria after ingestion of cranberry juice. JAMA 271(10): 751–754

    Article  PubMed  CAS  Google Scholar 

  5. Di Martino P, Agniel R, David K, et al. (2006) Reduction of Escherichia coli adherence to uroepithelial bladder cells after consumption of cranberry juice: a double-blind randomized placebo-controlled cross-over trial. World J Urol 24(1): 21–27

    Article  PubMed  Google Scholar 

  6. Duthie GG, Kyle JA, Jenkinson AM, et al. (2005) Increased salicylate concentrations in urine of human volunteers after consumption of cranberry juice. J Agric Food Chem 53(8): 2897–2900

    Article  PubMed  CAS  Google Scholar 

  7. Edzard Ernst (2005) Monographie, la Canneberge. Médecines alternatives, le guide critique. Éditions Elsevier, Paris

    Google Scholar 

  8. Foo L, Howell AB, Vorsa N (2000) A-Type proanthocyanidis trimers from cranberry that inhibit adherence of uropathogenic P-fimbriated Escherichia coli. J Nat Prod 63(9): 1225–1228

    Article  PubMed  CAS  Google Scholar 

  9. Fontanel D (2005) La Canneberge d’Amérique, Monographie. La Lettre de Phytothérapie, no 3

  10. Gettman MT, Ogan K, Brinkley LJ, Adams-Huet B (2005) Effect of cranberry juice consumption on urinary stone risk factors. J Urol 174(2): 590–594

    Article  PubMed  CAS  Google Scholar 

  11. Jackson SL, Boyko EJ, Scholes D, et al. (2004) Predictors of urinary tract infection after menopause: a prospective study. Am J Med 117(12): 903–911

    Article  PubMed  Google Scholar 

  12. Jepson R, Craig J (2008) Cranberries for preventing urinary tract infections. Cochrane Database Syst Rev 23(1): CD001321

    Google Scholar 

  13. Jepson RG, Milhaljevic L, Craig J (2004) Cranberries for preventing urinary tract infections (Review). Cochrane Database Syst Rev (2): CD001321.pub3. DOI: 10.1002/14651858

  14. Kessler T, Jansen B, Hesse A (2002) Effect of blackcurrant-, cranberry-and plum juice consumption on risk factors associated with kidney stone formation. Eur J Clin Nutr 56(10): 1020–1023

    Article  PubMed  CAS  Google Scholar 

  15. Leitao DP, Polizello AC, Ito IY, Spadaro AC (2005) Antibacterial screening of anthocyanic and proanthocyanic fractions from cranberry juice. J Med Food Spring 8(1): 36–40

    Article  CAS  Google Scholar 

  16. Lin YT, Labbe RG, Shetty K (2004) Inhibition of Listeria monocytogenes in fish and meat systems by use of oregano and cranberry phytochemical synergies. Chenoweth Laboratory, Department of Food Science, University of Massachusetts

  17. Monographie, la Canneberge, Institut européen des substances végétales

  18. Rindone JP, Murphy TW (2005) Warfarin-cranberry juice interaction resulting in profound hypoprothombinemia and bleeding. Am J Ther 13(3): 283–284

    Article  Google Scholar 

  19. Ruel G, Pomerleau S, et al. (2005) Changes in plasma antioxidant capacity and oxidized low-density lipoprotein levels in men after short-term cranberry juice consumption. Metabolism 54(7): 856–861

    Article  PubMed  CAS  Google Scholar 

  20. Ruel G, Pomerleau S, et al (2006) Favorable impact of low-calorie cranberry juice consumption on plasma HDL-cholesterol concentrations in men. Br J Nutr 86: 357–364

    Article  Google Scholar 

  21. Trautner BW, Hull RA, Darouiche RO (2005) Prevention of catheter-associated urinary tract infection. Curr Opin Infect Dis 18(1): 37–41

    Article  PubMed  Google Scholar 

  22. Weiss EI Houri-Haddad Y, Greenbaum Echman N, et al. (2005) Cranberry juice constituents affect influenza virus adhesion and infectivity. Antiviral Res 66(1): 9–12

    Article  PubMed  CAS  Google Scholar 

  23. Weiss EI, Kozlovsky A, Steinberg D, et al. (2004) A high molecular mass cranberry constituent reduces mutans streptococci level in saliva and inhibits in vitro adhesion to hydroxyapatite. FEMS Microbiol Lett 232(1): 89–92

    Article  PubMed  CAS  Google Scholar 

  24. Yamanaka A, Kimizuka R, Kato T, Okuda K (2004) Inhibitory effects of cranberry juice on attachment of oral streptococci and biofilm formation. Oral Microbiol Immunol 19(3): 150–154

    Article  PubMed  CAS  Google Scholar 

  25. Zhang L, Ma J, Pan K, et al. (2005) Efficacy of cranberry juice on Helicobacter pylori infection: a double-blind, randomized placebo-controlled trial. Helicobacter 10(2): 139–145. Related Articles, Links

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to B. Arnal.

About this article

Cite this article

Arnal, B., Bureau, L. & Jeune, R.I. La canneberge d’Amérique, propriétés et indications. Phytothérapie 6, 129–132 (2008). https://doi.org/10.1007/s10298-008-0303-5

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10298-008-0303-5

Mots clés

Keywords

Navigation