Résumé
L’olivier, arbre typiquement méditerranéen, se caractérise par un fruit, l’olive, dont l’huile est un composant essentiel du régime méditerranéen. Riche en acides gras insaturés, en vitamine E et en polyphénols (notamment en hydroxytyrosol), l’huile d’olive présente essentiellement des propriétés antioxydantes, antihypertensives, antiagrégantes plaquettaires responsables d’effets préventifs des maladies cardiovasculaires. La consommation régulière de cette huile a des effets bénéfiques dans certains troubles de l’appareil digestif et hépatobiliaire, dans l’ostéoporose, dans la prévention du vieillissement et dans le renforcement du système immunitaire. L’huile d’olive exerce un effet protecteur vis-à-vis de certaines tumeurs malignes et diminue l’incidence de certains types de cancer.
La feuille d’olivier est riche en triterpènes, flavonoïdes, sécoiridoïdes dont l’oleuropéoside et en acides phénols. Elle exerce des activités antioxydantes, hypotensives, spasmolytiques, hypoglycémiantes, hypocholestérolémiantes et antiseptiques, outre les propriétés diurétiques pour lesquelles elle est utilisée sous forme de spécialité phytothérapeutique.
Abstract
Olive tree is a typical Mediterranean tree whose fruit provides the olive oil which is an essential component of the Mediterranean diet. Olive oil, rich in unsaturated fatty acids, Vitamin E and polyphenols (mainly hydroxytyrosol), has antioxidant, antihypertensive and platelet antiaggregating properties, which have a preventive effect with respect to cardiovascular diseases. Regular consumption of olive oil has a beneficial effect on some ailments of the digestive and hepatobiliary systems and osteoporosis, as well as having anti-aging properties and strengthening the immune system. Olive oil also has a protective effect with respect to certain malignant tumours and decreases the incidence of certain types of cancer. The leaf of the olive tree is rich in triterpenoids, flavonoids, secoiridoids (including oleuropein) and phenolic acids. It has antioxidant, hypotensive, antispasmodic, hypoglycaemic, cholesterol-lowering and antiseptic properties, as well as being a diuretic, for which it is used in phytotherapy.
Bibliographie
Andreadou I, Iliodromitis EK, Mikros E, et al. (2006) The olive constituent oleuropein exhibits anti-ischemic, antioxidative, and hypolipidemic effects in anesthetized rabbits. J Nutr 136: 2213–2219
Aruoma OI, Deiana M, Jenner A, et al. (1998) Effect of hydroxytyrosol found in extra virgin olive oil on oxidative DNA damage and on low-density lipoprotein oxidation. J Agric Food Chem 46: 5181–5187
Benavente-Garcia O, Castillo J, Lorente J, et al. (2000) Antioxidant activity of phenolics extracted from Olea europaea L. leaves. Food Chem 68: 457–462
Bennani-Kabchi N, Fdhil H, Cherrah Y, et al. (1999) Effects of Olea europea var. oleaster leaves in hypercholesterolemic insulin-resistant sand rats. Therapie 54(6): 717–723
Bisignano G, Tomaino A, Lo Cascio R, et al. (1999) On the in vitro antimicrobial activity of oleuropein and hydroxytyrosol. J Pharm Pharmacol 51(8): 971–974
Bruneton J (1999) Pharmacognosie — Phytochimie — Plantes médicinales. 3e édition. Éd. Technique & Documentation, Paris
Covas MI (2007) Olive oil and the cardiovascular system (Review) Pharmacol Res 55: 175–186
De Lorgeril M, Salen P, Martin JL, et al. (1999) Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart Study. Circulation 99: 779–785
Fehri B, Aiache JM, Memmi A, et al. (1994) Hypotension, hypoglycémie et hypouricémie enregistrées à la suited’administration réitérée d’un extrait aqueux de feuilles d’Olea europaea L. J Pharm Bel 49(2): 101–108
Fehri B, Mrad S, Aiache JM, et al. (1995) Effects of Olea europaea L. extract on the rat isolated ileum and trachea. Phytother Res 9(6): 435–439
Gentilcore D, Chaikomin R, Jones KL, et al. (2006) Effects of fat on gastric emptying of and the glycemic, insulin, and incretin responses to a carbohydrate meal in type 2 diabetes. J Clin Endocrinol Metab 91(6): 2062–2067
Giamarellos-Bourboulis EJ, Geladopoulos T, et al. (2006) Oleuropein: a novel immunomodulator conferring prolonged survival in experimental sepsis by Pseudomonas aeruginosa. Shock 26(4): 410–416
Gilani AH, Khan AU, Shah AJ, et al. (2005) Blood pressure lowering effect of olive is mediated through calcium channel blockade. Int J Food Sci Nutr 56(8): 613–620
Gonzalez M, Zarzuelo A, Jomez M, et al. (1992) Hypoglycemic activity of olive leaf. Planta Med 58: 513–515
Gordon MH, Paiva-Martins F, Almeida M (2001) Antioxidant activity of hydroxytyrosol acetate compared with that of other olive oil polyphenols. J Agric Food Chem 49: 2480–2485
Hamdi HK, Castellon R (2005) Oleuropein, a non-toxic olive iridoid, is an anti-tumor agent and cytoskeleton disruptor. Biochem Biophys Res Comm 334: 769–778
Hansen K, Adsersen A, Brøgger Christensen S, et al. (1996) Isolation of an angiotensin converting enzyme (ACE) inhibitor from Olea europeae and Olea lancea. Phytomedicine 2: 319–325
Kergeta M, Kotnika P, Hadolinb M, et al. (2005) Phenols, proanthocyanidins, flavones and flavonols in some plant materials and their antioxidant activities. Food Chem 89(2): 191–198
Khan MY, Panchal S, Vyas N, et al. (2007) Olea europaea. Phyto-Pharmacol Review 1(1): 114–118
Khayyal MT, El-Ghazaly MA, Abdallah DM, et al. (2002) Blood pressure lowering effect of an olive leaf extract (Olea europaea) in L-NAME Hypertension in rats. Arzneimittelforschung 52(11): 797–802
Le Tutor B, Guedon D (1992) Antioxidative activities of Olea europea L. leaves and related phenolic compounds. Phytochemistry 31: 1173–1178
Manna C, D’Angelo S, Migliardi V, et al. (2002) Protective effect of the phenolic fraction from virgin olive oils against oxidative stress in human cells. J Agricult Food Chem 50: 6521–6526
Micol V, Caturla N, Pérez-Fons L, et al. (2005) The olive leaf extract exhibits antiviral activity against viral haemorrhagic septicaemia rhabdovirus (VHSV). Antiviral Res 66(2–3): 129–136
Owen RW, Giacosa A, Hull WE, et al. (2000) Olive-oil consumption and health: the possible role of antioxidants. Lancet Oncol 1(2): 107–112
Petroni A, Blasevich M, Salami M, et al. (1995) Inhibition of platelet aggregation and eicosanoid production by phenolic components of olive oil. Thrombosis Res 78: 151–160
Phytothérapie par les plantes — la santé par les plantes, ouvrage collectif (2007) Sélection du Reader’s Digest-Vidal, Paris
Polzonetti V, Egidi D, Vita A, et al. (2004) Involvement of oleuropein in (some) digestive metabolic pathways. Food Chem 88: 11–15
Puel C, Quintin A, Agalias A, et al. (2004) Olive oil and its main phenolic micronutrient (oleuropein) prevent inflammation-induced bone loss in the ovariectomised rat. Br J Nutr 92(1): 119–127
Puygrenier M, Besançon P (2001) Mediterranean diet and health: Current News And Prospects, John Libbey Eurotext, Montrouge
Ryan D, Antolovich M, Prenzler P, et al. (2002) Biotranformation of phenolic compounds in Olea europaea L. Sci Hortic 92: 147–176
Satoa H, Genet C, Strehle A, et al. (2007) Anti-hyperglycemic activity of a TGR5 agonist isolated from Olea europaea. Biochem Biophys Res Comm 362(3, 4): 793–798
Serrano P, Yago MD, Manas M, et al. (1997) Influence of type of dietary fat (olive and sunflower oil) upon gastric acid secretion and release of gastrin, somatostatin, and peptide YY in man. Digest Dis Sci 42(3): 440–442
Silvers KM, Woolley CC, Hamilton FC, et al. (2005) Randomised double-blind placebo-controlled trial of fish oil in the treatment of depression. Prostaglandins. Leukotr Ess Fatty Acids 72(3): 211–218
Somova LI, Shodeb FO, Ramnanana P, Nadara A (2003) Antihypertensive, antiatherosclerotic and antioxidant activity of triterpenoids isolated from Olea europaea, subspecies africana leaves. J Ethnopharmacol 84(2–3): 299–305
Togna GI, Togna AR, Franconi M, et al. (2003) Olive oil isochromans inhibit human platelet reactivity. J Nutr 133: 2532–2536
Vissers MN, Zock PL, Katan MB (2004) Bioavailability and antioxidant effects of olive oil phenols in humans: a review. Eur J Clin Nutr 58: 955–965
Visioli F, Galli C (1994) Oleuropein protects low density lipoprotein from oxidation. Life Sci 55(24): 1965–1971
Visioli F, Bellomo G, Galli C (1998) Free radical-scavenging properties of olive oil polyphenols. Biochem Biophys Res Comm 247(1): 60–64
Visioli F, Galli C (2001) Antiatherogenic components of olive oil. Curr Atheroscl Rep 3: 64–67
Visioli F, Claudio G (2002) Biological properties of olive oil phytochemicals. Crit Rev Food Sci Nutr 42(3): 209–221
Warchol M, Perrin S, Grill JP (2002) Oleuropein ïnhibits LDL oxidation induced by cooking oil frying by-products and platelet aggregation induced by platelet-activating factor. Lebenson Wiss Technol 35(6): 479–484
Weiss RF, Fintelmann V (2000) Herbal Medicine. 2e édition, Thieme, Stuttgart — New York
Zarzuelo A, Duarte J, Jiménez J, et al. (1991) Vasodilator effect of olive leaf. Planta Med 57: 417–419
Author information
Authors and Affiliations
Corresponding author
About this article
Cite this article
Ghedira, K. L’olivier. Phytothérapie 6, 83–89 (2008). https://doi.org/10.1007/s10298-008-0294-2
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10298-008-0294-2
Mots clés
- Olivier
- Olea europea
- Olive
- Feuilles
- Propriétés pharmacologiques
- Actions préventives
- Maladies cardiovasculaires
- Cancers