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Caractérisation et bioévaluation des polyphénols: nouveaux domaines d’application en santé et nutrition

Characterization and bio-evaluation of polyphenols from some plum varieties and new fields for their use in health and diet

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  • Phytonutrition Expérimentale
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Phytothérapie

Résumé

Dans cette étude, nous avons montré que plusieurs variétés de prunes permettent la protection des granulocytes contre le stress oxydant par leur potentiel inhibiteur d’accumulation intracellulaire des espèces réactives de l’oxygène (ERO) qui sont très cytotoxiques et impliquées dans de nombreux troubles. Ainsi, la consommation de 100 g de prunes fraîches correspondrait en effet antioxydant à l’équivalent de 614 et 2 138 mg de vitamine C. Le profil chimique des polyphénols majoritaires des prunes a été établi par nos études grâce à des méthodes analytiques de chromatographie (CLHP) montrant que l’acide néochlorogénique est le polyphénol prédominant. Les prunes se sont également révélées une source de polyphénols ayant un double effet: antioxydant et anxiolytique, tels que l’acide chlorogénique, ce qui donne aux polyphénols de nouveaux champs d’applications dans le domaine de la prévention.

Abstract

In the present study, we have shown that plums protected granulocyte cells from oxidative stress by their potential to inhibit the intracellular reactive oxygen species accumulation. The consumption of 100 g of fresh plums can provide antioxidants equivalent to 613.98–2137.59 mg of vitamin C. The major polyphenols in plums were identified and quantified using reversed-phase high-performance liquid chromatography (HPLC), which revealed that neochlorogenic acid was the predominant polyphenol. Plums are a source of polyphenols with dual effects: antioxidant and anxiolytic, like chlorogenic acid, which may provide health-promoting advantages to the consumer.

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Correspondence to R. Soulimani.

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Bouayed, J., Rammal, H., Younos, C. et al. Caractérisation et bioévaluation des polyphénols: nouveaux domaines d’application en santé et nutrition. Phytothérapie 6, 71–74 (2008). https://doi.org/10.1007/s10298-008-0292-4

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  • DOI: https://doi.org/10.1007/s10298-008-0292-4

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