Le Svetol ®, un extrait de café vert décaféiné, induit une perte de poids et augmente le ratio masse maigre sur masse grasse chez des volontaires en surcharge pondérale

Svetol®, green coffee extract, induces weight loss and increases the lean to fat mass ratio in volunteers with overweight problem

Résu mé

Pour tester les effets du Svetol®, un extrait de café vert décaféiné possédant un ratio spécifique entre l’acide 5-caféyl-quinique (acide chlorogénique) et les autres isomères d’acides caféylquiniques, sur la perte de poids, 50 volontaires ayant un indice de masse corporelle (IMC) supérieur à 25 ont été sélectionnés. Ils ont été randomisés en deux groupes : l’un (n = 20) recevant le placebo, l’autre (n = 30) recevant le Svetol® en parallèle d’une alimentation légèrement hypocalorique. Chaque volontaire consomme une capsule de Svetol® ou de placebo deux fois par jour pendant 60 jours, au moment des repas principaux. Le poids, l’IMC, le ratio masse maigre/masse grasse (MM/MG) et l’auto-évaluation de l’aspect physique ont été déterminés à Jo et J60. Après 60 jours de traitement, une réduction significative du poids de 4,97 +/- 0,32 kg (5,7 %) a été observée dans le groupe Svetol® comparé au groupe contrôle (p < 0,001). Le ratio MM/MG est augmenté de façon significative dans le groupe Svetol® comparé au groupe contrôle : 4,1 +/- 0,7 %vs 1,6 +/- 0,6 % respectivement (p < 0,01). Ces résultats démontrent que le Svetol® est capable d’augmenter l’effet d’une alimentation légèrement hypocalorique chez des volontaires ayant des problèmes de surpoids. Cet effet pourrait être expliqué par une meilleure utilisation des graisses et par la prévention de leur accumulation.

Abstract

In order to test the effects of Svetol®, a green coffee extract with specific ratio between 5-caffeoylquinic acid and others caffeoylquinic acid isomers, on weight loss, 50 volunteers with body mass index superior to 25 were selected. They were randomized in two groups, control group (n = 20) receiving placebo, treated group (n = 30) receiving Svetol® with bland low calory diet. Each volunteer took one capsule of Svetol® or placebo twice a day with main meal, for 60 days. Changes in weight, body mass index (BMI), Muscle Mass/Fat Mass ratio (MM/FM) and self-evaluation of physical aspect were recorded at To and T60. After 60 days of treatment, a significant reduction in weight of 4.97 +/- 0.32 kg (5.7 %) was observed in the Svetol® group compared to control group (p < 0.001). Moreover, MM/FM ratio was increased significantly in Svetol® group compared to control group : 4.1 +/-0.7 %vs 1.6 +/- 0.6 respectively (p < 0.01). The significant decrease of weight and increase of MM/FM ratio showed that Svetol® is able to exacerbate effect of a bland low caloric diet in volunteers who have overweight. This effect could be explained by increasing the consumption of fatty deposits and by preventing them from being accumulated.

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Correspondence to O. Dellalibera.

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Dellalibera, O., Lemaire, B. & Lafay, S. Le Svetol ®, un extrait de café vert décaféiné, induit une perte de poids et augmente le ratio masse maigre sur masse grasse chez des volontaires en surcharge pondérale. Phytothérapie 4, 194 (2006). https://doi.org/10.1007/s10298-006-0181-7

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Mots clés

  • Acides chlorogéniques
  • Svetol®
  • Poids
  • Masse maigre/masse grasse (MM/MG)

Keywords

  • Chlorogenic acids
  • Svetol®
  • Weight
  • Muscle
  • mass/fat mass ratio