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Lovastatin inhibits its own synthesis in Aspergillus terreus

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Journal of Industrial Microbiology and Biotechnology

Abstract

Lovastatin suppresses its own synthesis in the microfungus Aspergillus terreus. The inhibitory effect was documented by spiking identical batch cultures with pure lovastatin (0, 50, 100 and 250 mg/l) 24 h after initiation from spores.

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Acknowledgements

This research was supported by the Ministerio de Ciencia y Tecnología (MYCT) and FEDER (PPQ2000-0032-P4-02).

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Authors and Affiliations

  1. Department of Chemical Engineering, University of Almería, 04120, Almería, Spain

    J. L. Casas López, E. M. Rodríguez Porcel, M. A. Vilches Ferrón, J. A. Sánchez Pérez & J. M. Fernández Sevilla

  2. Institute of Technology and Engineering, Massey University, Private Bag 11 222, Palmerston North, New Zealand

    Y. Chisti

Authors
  1. J. L. Casas López
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  2. E. M. Rodríguez Porcel
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  3. M. A. Vilches Ferrón
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  4. J. A. Sánchez Pérez
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  5. J. M. Fernández Sevilla
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  6. Y. Chisti
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Correspondence to J. L. Casas López.

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Casas López, J.L., Rodríguez Porcel, E.M., Vilches Ferrón, M.A. et al. Lovastatin inhibits its own synthesis in Aspergillus terreus . J IND MICROBIOL BIOTECHNOL 31, 48–50 (2004). https://doi.org/10.1007/s10295-004-0108-y

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  • DOI: https://doi.org/10.1007/s10295-004-0108-y

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