Skip to main content
Log in

Auxarthrol A and auxarthrol B: two new tetrahydoanthraquinones from Auxarthron umbrinum

  • Original Paper
  • Published:
Journal of Industrial Microbiology and Biotechnology

Abstract

Two new 1,2,3,4-tetrahydroanthraquinones, auxarthrol A (compound 1) and auxarthrol B (2), along with three known pyrrolyloctatetraenyl-α-pyrone pigments, auxarconjugatin A (3), auxarconjugatin B (4) and rumbrin (5), were isolated from the fungus Auxarthron umbrinum. Structure elucidation of new compounds 1 and 2 was accomplished by spectroscopic data analysis while identification of the known pigments (3–5) was achieved by LC-MS-photodiode array detection.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1A–D

Similar content being viewed by others

References

  1.  Alvi KA (1999) A strategy for rapid identification of novel therapeutic leads from natural products. In: Cutler SJ, Cutler HJ (eds) Biologically active natural products: pharmaceuticals. CRC Press, Boca Raton, Fla., pp 185–195

  2.  Alvi KA (2001) Screening natural products: bioassay-directed isolation of active compounds by dual-mode CCC. J Liq Chromatogr Relat Technol 24:1765–1773

    Article  CAS  Google Scholar 

  3.  Becker AM, Rickards RW, Schmalzl KJ, Yick HC (1978) Metabolites of Dactylaria lutea: the structures of dactylariol and the antiprotozoal antibiotic dactylarin. J Antibiot 31:324–329

    CAS  PubMed  Google Scholar 

  4.  Domsch KH, Gams W, Anderson TH (1993) Compendium of soil fungi. IHW, Eching pp 481–487

  5.  Gunther H (1994) NMR spectroscopy: basic principles, concepts, and applications in chemistry. Wiley, New York, pp 70–133

    Google Scholar 

  6.  Hosoe T, Fukushima K, Takizawa K, Miyaji M, Kawai K (1999) Three pyrrolyloctatetraenyl-α-pyrones from Auxarthron conjugatum. Phytochemistry 52:459–463

    Article  CAS  Google Scholar 

  7.  Kasai M, Shirahata K, Ishii S, Mineura K, Marumo H, Tanaka H, Omura SJ (1979) Structure of nanaomycin E, a new nanaomycin. J Antibiot 32:442–445

    CAS  PubMed  Google Scholar 

  8.  Noda T, Take T, Watanabe T, Abe J (1970) The structure of bostrycin. Tetrahedron 26:1339–1346

    Article  CAS  PubMed  Google Scholar 

  9.  Okabe T, Nomoto K, Tanaka N (1986) Lactoquinomycin B, a novel antibiotic. J Antibiot 39:1–5

    CAS  PubMed  Google Scholar 

  10.  Okamura N, Haraguchi H, Hashimoto K, Yagi A (1993) Altersolanol-related antimicrobial compounds from a strain of Alternaria solani. Phytochemistry 34:1005–1009

    Article  CAS  Google Scholar 

  11.  Stoessl A (1969) Some metabolites of Alternaria solani. Can J Chem 47:67–76

    Google Scholar 

  12.  Suemitsu R, Kitagawa N, Horie S, Kazawa K, Harada T (1978) Isolation and identification of Altersolanol B (7-methoxy-2-methyl-(2R, 3S)-1,2,3,4-tetrahydro-2,3,5-trihydroxyantraquinone) from the mycelium of Alternaria porri. Agric Biol Chem 42:1801–1802

    CAS  Google Scholar 

  13.  Yamagishi Y, Shindo K, Kawai HJ (1993) Rumbrin: a new cytoprotective substance produced by Auxarthron umbrinum. Antibiotics 46:884–891

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Khisal A. Alvi.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Alvi, K.A., Rabenstein, J. Auxarthrol A and auxarthrol B: two new tetrahydoanthraquinones from Auxarthron umbrinum . J IND MICROBIOL BIOTECHNOL 31, 11–15 (2004). https://doi.org/10.1007/s10295-003-0106-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10295-003-0106-5

Keywords

Navigation