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What lies beneath: cyclical giant bursts of SNA during vasovagal syncope

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Fig. 1
Fig. 2

Data availability

Raw data of the nerve recordings is available from the author on request.

References

  1. Jardine DL, Wieling W, Brignole M, Lenders J, Sutton R, Stewart J (2018) The pathophysiology of the vasovagal response. Heart Rhythm 15:921–929

    Article  PubMed  Google Scholar 

  2. Rowell LB (1993) Human cardiovascular control. Oxford University Press, Oxford, pp 1–162

    Book  Google Scholar 

  3. Hagbarth KE, Vallbo AB (1968) Pulse and respiratory grouping of sympathetic impulses in human muscle nerves. Acta Physiol Scand 74:96–108

    Article  CAS  PubMed  Google Scholar 

  4. Sundlof G, Wallin BG (1978) Human muscle nerve sympathetic activity at rest, relationship to blood pressure and age. J Physiol 274:621–637

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Parati G, Di Renzo M, Mancia G (2000) How to measure baroreflex activity sensitivity: from the cardiovascular laboratory to daily life. J Hypertens 18:7–19

    Article  CAS  PubMed  Google Scholar 

  6. Kienbaum P, Karlsson T, Sverrisdottir YB, Elam M, Wallin G (2001) Two sites for modulation of human sympathetic activity by arterial baroreceptors? J Physiol 531:861–869

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Wallin BG, Delius W, Sundlof G (1974) Human muscle nerve sympathetic activity in cardiac arrhythmias. Scand J Clin Lab Invest 34:293–300

    Article  CAS  PubMed  Google Scholar 

  8. Hagbarth KE (1979) Exteroceptive, proprioceptive and sympathetic activity recorded with microelectrodes from human peripheral nerves. Mayo Clin Proc 54:353–365

    CAS  PubMed  ADS  Google Scholar 

  9. Delius W, Hagbarth KE, Hongell A, Wallin BG (1972) Manoeuvres affecting sympathetic outflow in human skin nerves. Acta Physiol Scand 84:177–186

    Article  CAS  PubMed  Google Scholar 

  10. Fagius J, Wallin BG, Sundlof G, Nerhed C, Englesson S (1985) Sympathetic outflow in man after anaesthesia of the glossopharyngeal and vagus nerves. Brain 108:423–438

    Article  PubMed  Google Scholar 

  11. Iwase S, Mano T, Kamiya A, Niimi Y, Fu Q, Suzumura A (2002) Syncopal attack alters the burst properties of muscle sympathetic nerve activity in humans. Autonom Neurosci 95:141–145

    Article  Google Scholar 

  12. Yang H, Cooke W, Reed K, Carter J (2012) Sex differences in hemodynamic and sympathetic neural firing patterns during orthostatic challenge in humans. J Appl Physiol 112:1744–1751

    Article  PubMed  Google Scholar 

  13. Montano N, Gnecchi-Ruscone T, Porta A, Lombradi F, Malliani A, Barman S (1996) Presence of vasomotor and respiratory rhythms in the discharge of single medullary neurones involved in the regulation of the cardiovascular system. J Autonom Nerv Syst 57:116–122

    Article  CAS  Google Scholar 

  14. Cogliata C, Magatelli R, Montano N, Narciewicz K, Somers VK (2000) Detection of low- and high-frequency rhythms in the variability of skin sympathetic nerve activity. Am J Physiol Heart Circ Physiol 278:H1256–H1260

    Article  Google Scholar 

  15. Lempert T, Bauer M, Schmidt D (1994) Syncope: a videometric analysis of 56 episodes. Ann Neurol 36:233–237

    Article  CAS  PubMed  Google Scholar 

  16. Seitz M, Brown R, Macefield V (2013) Inhibition of augmented muscle vasoconstrictor drive following asphyxic apnoea in awake human subjects is not affected by relief of chemical drive. Exp Physiol 98:405–414

    Article  CAS  PubMed  Google Scholar 

  17. Macefield VG, Elam M (2002) Prolonged surges of baroreflex-resistant muscle sympathetic drive during periodic breathing. Clin Auton Res 12:165–169

    Article  PubMed  Google Scholar 

  18. Macefield VG (2021) Recording and quantifying sympathetic outflow to muscle and skin in humans: methods, caveats and challenges. Clin Auton Res 31:59–75

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Departments of Medicine and General Medicine, Christchurch Hospital, 2, Riccarton Ave, Christchurch, 4710, New Zealand

    D. L. Jardine

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  1. D. L. Jardine
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Correspondence to D. L. Jardine.

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Jardine, D.L. What lies beneath: cyclical giant bursts of SNA during vasovagal syncope. Clin Auton Res 34, 213–217 (2024). https://doi.org/10.1007/s10286-023-01009-w

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