Gastrointestinal function in dementia with Lewy bodies: a comparison with Parkinson disease

Abstract

Purpose

To investigate gastrointestinal function in dementia with Lewy bodies and Parkinson disease.

Methods

We examined gastric emptying and colonic transit time in 19 dementia with Lewy bodies and 46 Parkinson disease patients.

Results

Gastric emptying was longer in dementia with Lewy bodies than in Parkinson disease (p = 0.014). Colonic transit time tended to be longer in dementia with Lewy bodies than in Parkinson disease. There was no relationship between gastric emptying and colonic transit time, nor between gastric emptying, colonic transit time and age.

Conclusion

Gastric emptying was prolonged in dementia with Lewy bodies compared to Parkinson disease.

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Affiliations

Authors

Contributions

Hirokazu Doi had a role in: acquisition, analysis and interpretation of data. Ryuji Sakakibara had a role in: study concept and design, acquisition of subjects and/or data, analysis and interpretation of data, and preparation of manuscript. Mitsutoshi Sato had a role in: acquisition, analysis and interpretation of data. Masayuki Masuda had a role in: acquisition, analysis and interpretation of data. Fuyuki Tateno had a role in: acquisition, analysis and interpretation of data. Yosuke Aiba had a role in: acquisition, analysis and interpretation of data. Masahiko Kishi had a role in: acquisition of subjects and/or data. Tomonori Yamanishi had a role in: review of data. Tatsuya Yamamoto had a role in: review of data. Katsuyoshi Matsuoka had a role in: acquisition of subjects and/or data.

Corresponding author

Correspondence to Ryuji Sakakibara.

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Doi, H., Sakakibara, R., Masuda, M. et al. Gastrointestinal function in dementia with Lewy bodies: a comparison with Parkinson disease. Clin Auton Res 29, 633–638 (2019). https://doi.org/10.1007/s10286-019-00597-w

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Keywords

  • Dementia with Lewy bodies
  • Parkinson disease
  • Gastric emptying
  • Colonic transit time
  • Constipation