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Acute inhalation of vaporized nicotine increases arterial pressure in young non-smokers: a pilot study

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Abstract

Purpose

Electronic cigarettes are growing in popularity, but the physiological consequences of vaporized nicotine are unknown.

Methods

Twenty healthy non-smokers inhaled vaporized nicotine and placebo (randomized).

Results

Nicotine inhalation was associated with higher arterial pressures in the seated position, and increased arterial pressures in the head-up positions with no other effects on autonomic control.

Conclusions

Our results show that vaporized nicotine inhalation is not innocuous. Longitudinal studies in otherwise healthy non-smokers should be conducted.

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Acknowledgments

This study was supported by a Collaborative Seed Grant through the Office of the Vice President for Research, University of Texas at San Antonio, San Antonio Texas. We appreciate the technical assistance of Ms. Audrey Ramirez.

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Authors and Affiliations

  1. Department of Kinesiology, Health, and Nutrition, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX, 78249, USA

    William H. Cooke, Anusheela Pokhrel, Colin Dowling & Donovan L. Fogt

  2. Department of Integrative Physiology and Anatomy, The University of North Texas Health Science Center, Fort Worth, TX, 76107, USA

    Caroline A. Rickards

Authors
  1. William H. Cooke
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  2. Anusheela Pokhrel
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  3. Colin Dowling
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  4. Donovan L. Fogt
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  5. Caroline A. Rickards
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Corresponding author

Correspondence to William H. Cooke.

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The authors declare that they have no conflict of interest.

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Cooke, W.H., Pokhrel, A., Dowling, C. et al. Acute inhalation of vaporized nicotine increases arterial pressure in young non-smokers: a pilot study. Clin Auton Res 25, 267–270 (2015). https://doi.org/10.1007/s10286-015-0304-z

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  • DOI: https://doi.org/10.1007/s10286-015-0304-z

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