Electronic cigarettes are growing in popularity, but the physiological consequences of vaporized nicotine are unknown.
Twenty healthy non-smokers inhaled vaporized nicotine and placebo (randomized).
Nicotine inhalation was associated with higher arterial pressures in the seated position, and increased arterial pressures in the head-up positions with no other effects on autonomic control.
Our results show that vaporized nicotine inhalation is not innocuous. Longitudinal studies in otherwise healthy non-smokers should be conducted.
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This study was supported by a Collaborative Seed Grant through the Office of the Vice President for Research, University of Texas at San Antonio, San Antonio Texas. We appreciate the technical assistance of Ms. Audrey Ramirez.
Conflict of interest
The authors declare that they have no conflict of interest.
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Cooke, W.H., Pokhrel, A., Dowling, C. et al. Acute inhalation of vaporized nicotine increases arterial pressure in young non-smokers: a pilot study. Clin Auton Res 25, 267–270 (2015). https://doi.org/10.1007/s10286-015-0304-z
- Electronic cigarettes
- Head-up tilt
- Blood pressure
- Autonomic control