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Successful long-term ambulatory norepinephrine infusions in a patient with pure autonomic failure

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Abstract

We present a case study of a patient with pure autonomic failure who was successfully treated with ambulatory norepinephrine (NE) infusions over a 9-year-period of time before death occurred unexpectedly. Given this patient’s response to the NE infusion treatment, we discuss the option of ambulatory NE infusions as a treatment for severe orthostatic hypotension that is refractory to common treatments.

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Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

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Author notes

  1. A. Zekeridou

    Present address: Laboratory of Neuroimmunology, Mayo Clinic College of Medicine, Rochester, MN, 55905, USA

Authors and Affiliations

  1. Nerve-Muscle Unit, Department of Clinical Neurosciences, Lausanne University Hospital CHUV, Lausanne, Switzerland

    A. Zekeridou, P. Michel, F. Medlin & T. Kuntzer

  2. Department of Internal Medicine, Fribourg University Hospital, Fribourg, Switzerland

    D. Hayoz

  3. Laboratory Medicine Service, Division of Neurology, Department of Clinical Neurosciences, Department of Genetic Medicine and Laboratory, Geneva University Hospital HUG, Geneva, Switzerland

    P. H. Lalive

Authors
  1. A. Zekeridou
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  2. P. Michel
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  3. F. Medlin
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  4. D. Hayoz
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  5. P. H. Lalive
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  6. T. Kuntzer
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Corresponding author

Correspondence to A. Zekeridou.

Additional information

Drs. A. Zekeridou and P. Michel contributed equally to this article as joint first authors.

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Zekeridou, A., Michel, P., Medlin, F. et al. Successful long-term ambulatory norepinephrine infusions in a patient with pure autonomic failure. Clin Auton Res 25, 251–253 (2015). https://doi.org/10.1007/s10286-015-0290-1

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  • DOI: https://doi.org/10.1007/s10286-015-0290-1

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