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Reduced water induced skin wrinkling in congestive heart failure


Water immersion skin wrinkling (WISW) of the fingertips may reflect central autonomic function. We found lower WISW in 60 heart failure patients versus controls (1.6 ± 0.67 vs. 2.5 ± 1.1, p < 0.001), linking a cardiovascular disorder to reduced WISW.

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Correspondence to Jason M. Lazar.

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Kamran, H., Salciccioli, L. & Lazar, J.M. Reduced water induced skin wrinkling in congestive heart failure. Clin Auton Res 21, 361–362 (2011).

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  • Congestive Heart Failure
  • Heart Rate Variability
  • Beta Blocker
  • Multivariate Linear Regression
  • Autonomic Dysfunction