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DBH deficiency in an elderly patient: efficacy and safety of chronic droxidopa

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Abstract

We describe the effects of chronic droxidopa in a patient with Dopamine beta-hydroxylase deficiency diagnosed at the age of 73. Investigations were performed to assess sympathetic activity (MIBG scintigraphy, catecholamines) and cardiovascular droxidopa safety.

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Authors and Affiliations

  1. INSERM U858 équipe 8, 31432, Toulouse, France

    Fabien Despas, A. Pathak & J. M. Senard

  2. Institut de Médecine Moléculaire de Rangueil, Université de Toulouse, UPS, 31432, Toulouse, France

    Fabien Despas, A. Pathak & J. M. Senard

  3. Department of Clinical Pharmacology, CHU de Toulouse, 31432, Toulouse, France

    Fabien Despas, A. Pathak & J. M. Senard

  4. Department of Cardiology, CHU de Toulouse, 31432, Toulouse, France

    M. Berry, P. Massabuau & M. Galinier

  5. Department of Nuclear Medicine, CHU de Toulouse, 31432, Toulouse, France

    R. Cagnac

  6. Department of Internal Medicine, CHU Dupuytren, 87000, Limoges, France

    E. Liozon

  7. Laboratoire de Pharmacologie clinique, Faculté de médecine, 37 Allées J. Guesde, 31000, Toulouse Cedex, France

    Fabien Despas

Authors
  1. Fabien Despas
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  2. A. Pathak
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  3. M. Berry
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  4. R. Cagnac
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  5. P. Massabuau
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  6. E. Liozon
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  7. M. Galinier
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  8. J. M. Senard
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Corresponding author

Correspondence to Fabien Despas.

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Despas, F., Pathak, A., Berry, M. et al. DBH deficiency in an elderly patient: efficacy and safety of chronic droxidopa. Clin Auton Res 20, 205–207 (2010). https://doi.org/10.1007/s10286-009-0049-7

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  • DOI: https://doi.org/10.1007/s10286-009-0049-7

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