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Reproducibility of heart rate variability and blood pressure variability in individuals with spinal cord injury

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Abstract

Individuals with spinal cord injury (SCI) are prone to orthostatic intolerance and an increased risk of cardiovascular disease. The use of heart rate variability (HRV) and blood pressure variability (BPV) as indices of cardiovascular regulation would be valuable in this population; however, their reproducibility has yet to be tested in those with SCI. The purpose of this study was to examine the day-to-day reproducibility of resting HRV and BPV in individuals with SCI. Ten individuals (age 35.9±13.2 yrs) with chronic (5.4±7.7 years post injury) SCI (C4-T12; ASIA A-C) participated. On two occasions within a two-week period, 10-minute supine electrocardiogram and Finapres blood pressure recordings were obtained during spontaneous breathing. Computer software calculated frequency domain measures of HRV and BPV (Low frequency (LF) power, High frequency (HF) power, and LF:HF ratio). Intraclass correlations coefficients (R) were used as an index of day-to-day reproducibility, and analyses were conducted on all participants and only those with tetraplegia. For HRV, measures of heart rate, LF, and LF:HF were found to be highly reproducible (R=0.82–0.88); however, the reproducibility of HF was found to be poor (all participants: R=0.53, tetraplegia: R=0.66). Measures of blood pressure as well as systolic BPV also showed high reproducibility (R=0.72–0.93). Measures of diastolic BPV were less reproducible but still acceptable (R=0.71–0.89) with the exception of LF:HFDBP (R=0.51). In conclusion, despite the autonomic dysfunction associated with SCI, measures of HRV and BPV may still be used as reproducible indices of autonomic cardiovascular regulation in this population.

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Authors and Affiliations

  1. Dept. of Kinesiology, McMaster University, Hamilton (OT), Canada

    David S. Ditor Ph.D., Maureen J. MacDonald, Neil McCartney & Audrey L. Hicks

  2. 939 Western Rd, Apt. #B10, London (OT), Canada N6G 1G3

    David S. Ditor Ph.D.

  3. Dept. of Medicine, McMaster University, Hamilton (OT), Canada

    Mark V. Kamath & Joanne Bugaresti

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  1. David S. Ditor Ph.D.
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  2. Mark V. Kamath
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  3. Maureen J. MacDonald
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  4. Joanne Bugaresti
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  5. Neil McCartney
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  6. Audrey L. Hicks
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Correspondence to David S. Ditor Ph.D..

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Ditor, D.S., Kamath, M.V., MacDonald, M.J. et al. Reproducibility of heart rate variability and blood pressure variability in individuals with spinal cord injury. Clin Auton Res 15, 387–393 (2005). https://doi.org/10.1007/s10286-005-0293-4

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  • DOI: https://doi.org/10.1007/s10286-005-0293-4

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