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Interval training in elderly men increases both heart rate variability and baroreflex activity

Clinical Autonomic Research Aims and scope Submit manuscript

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Abstract

Aims

Autonomic nervous system activity decreases continuously with age and appears to be a powerful predictor of disease and death. Attempts are thus made to reactivate autonomic drive with the intent of improving health.

Methods

We assessed maximal oxygen consumption (VO2max), auto- nomic nervous system activity by heart rate variability (HRV) analysis and spontaneous cardiac baroreflex activity (SBR) in eleven elderly men (73.5±4.2 years) before and after a 14-week program of intensive cycloergometer interval training. The standard HRV indices were calculated using time domain (mean RR, PNN50, RMSSD, SDNN, SDANN and SDNNIDX), and Fourier transform (total power, ULF,VLF, LF, LFnu, HF, HFnu and LF/HF) analyses of 24-hour, daytime and nighttime Holter recordings. The SBR was calculated from 15-minute recordings of spontaneous blood pressure and RR interval variations using the sequence (slope, slSBR) and cross-spectral (αSBRHF and αSBRLF) methods.

Results

After the training period,VO2max increased by 18.6 % (26.8±4.4 to 31.8±5.2 ml · kg–1 · min–1, p<0.01). The nocturnal parasympathetic indices of HRV increased (PNN50: 3.05±2.21 to 5.00±2.87%, RMSSD: 29.1±7.6 to 38.8±10.9 ms, HF: 117±54 to 194±116 ms2/Hz, all p<0.05) as did the SBR indices (slSBR: 7.0±1.8 to 9.8±2.1 ms·mmHg–1, p<0.01; αSBRHF: 6.9±2.2 to 10.5±3.7 ms ·mmHg–1, p<0.05; αSBRLF: 5.3±2.3 to 6.9±3.1 ms ·mmHg–1, p=0.22).

Conclusion

Intensive endurance training in elderly men enhanced parasympathetic parameters of HRV and, interestingly, of SBR. Physiological mechanisms and long-term clinical effects on health status should be further investigated.

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Authors and Affiliations

  1. Laboratoire de Physiologie, GIP E2S, Université de Saint-Etienne, Saint-Etienne, France

    Vincent Pichot, Frédéric Roche, Christian Denis, Martin Garet, David Duverney, Frédéric Costes & Jean-Claude Barthélémy

  2. Laboratoire de Physiologie, CHU Nord—Niveau 6, 42055, Saint-Etienne, Cedex 2, France

    Vincent Pichot

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  1. Vincent Pichot
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  2. Frédéric Roche
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  7. Jean-Claude Barthélémy
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Correspondence to Vincent Pichot.

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Pichot, V., Roche, F., Denis, C. et al. Interval training in elderly men increases both heart rate variability and baroreflex activity. Clin Auton Res 15, 107–115 (2005). https://doi.org/10.1007/s10286-005-0251-1

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  • DOI: https://doi.org/10.1007/s10286-005-0251-1

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