Imaging Properties of Additive Manufactured (3D Printed) Materials for Potential Use for Phantom Models
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Over the last few decades, there has been growing interest in the application of additive manufacturing (AM) or 3D printing for medical research and clinical application. Imaging phantoms offer clear benefits in the way of training, planning, and quality assurance, but the model’s availability per catalog tend to be suited for general testing purposes only. AM, on the contrary, offers flexibility to clinicians by enabling custom-built phantoms based on specific interests or even individual patient needs. This study aims to quantify the radiographic properties (ultrasound, magnetic resonance imaging, and computed tomography) of common additive manufacturing technologies and to discuss potential opportunities to fabricate imaging phantoms. Test phantoms were composed of samples from the three most common AM styles, namely PolyJet, fused deposition modeling (FDM), and stereolithography (SLA). Test imaging of the phantoms was performed on ultrasound, MRI, and CT and reviewed and evaluated with radiology software. The ultrasound images showed clearly defined upper and lower edges of the material but did not demonstrate distinct differences in internal echogenicity between materials. The MR scans revealed a distinct signal intensity difference between the model (17 grayscale value) and the printer support (778 grayscale value). Finally, the CT images showed a slight variation between the plastic (82 HU) and rubber (145 HU) materials. The radiographic properties of AM offer a clear opportunity to create basic two- or three-material phantoms. These would be high-accuracy and cost-effective models. Although the materials currently available are not suitable for complex multi-material applications as realistic as true human anatomy, one can easily foresee the development of new materials with broader density in the near future.
Keywords3D printing Additive manufacturing Phantoms Simulation
Fused deposition modeling
We would like to thank Glenn Ferrick (MR), Patricia Mecca (CT/MR), Colleen Flowers (CT), Lamont Hill (US), Marcy L. Hutchinson (US), and team for assisting in the scan of phantoms.
Availability of Data and Materials
Data will be made available on request. The authors have the right to share the data used in this research and will provide it upon request.
ES and RS participated in the conception and design of the study, data analysis, and interpretation. ES fabricated models and oversaw scanning. KB and ES completed scan interpretation and data collection. All authors drafted the manuscript and approved the final version.
Compliance with Ethical Standards
The authors declare that they have no conflict of interest.
- 6.Wood S, Krishnamurthy N, Santini T, Raval S, Farhat N, Holmes JA, Ibrahim TS: Design and fabrication of a realistic anthropomorphic heterogeneous head phantom for MR purposes. PLoS One. 12, 2017. https://doi.org/10.1371/journal.pone.0183168
- 8.Hazelaar C, Van Eijnatten M, Dahele M, et al: Using 3D printing techniques to create an anthropomorphic thorax phantom for medical imaging purposes. 2017.Google Scholar
- 9.Cerviño L, Soultan D, Cornell M, Yock A, Pettersson N, Song WY, Aguilera J, Advani S, Murphy J, Hoh C, James C, Paravati A, Coope R, Gill B, Moiseenko V: A novel 3D-printed phantom insert for 4D PET/CT imaging and simultaneous integrated boost radiotherapy. Med Phys. 44:5467–5474, 2017. https://doi.org/10.1002/mp.12495 CrossRefGoogle Scholar
- 10.Javan R, Cho AL: An Assembled Prototype Multimaterial Three-Dimensional–Printed Model of the Neck for Computed Tomography– and Ultrasound-Guided Interventional Procedures. https://doi.org/10.1097/RCT.0000000000000630
- 11.Ceh J, Youd T, Mastrovich Z, Peterson C, Khan S, Sasser T, Sander I, Doney J, Turner C, Leevy W: Bismuth infusion of ABS enables additive manufacturing of complex radiological phantoms and shielding equipment. Sensors (Switzerland). 17, 2017. https://doi.org/10.3390/s17030459
- 16.West SJ, Mari JM, Khan A, Wan JHY, Zhu W, Koutsakos IG, Rowe M, Kamming D, Desjardins AE: Development of an ultrasound phantom for spinal injections with 3-dimensional printing. Regional Anesthesia and Pain Medicine. 39:429–433, 2014. https://doi.org/10.1097/AAP.0000000000000136 CrossRefGoogle Scholar