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Clinical Applications of a CT Window Blending Algorithm: RADIO (Relative Attenuation-Dependent Image Overlay)


A methodology is described using Adobe Photoshop and Adobe Extendscript to process DICOM images with a Relative Attenuation-Dependent Image Overlay (RADIO) algorithm to visualize the full dynamic range of CT in one view, without requiring a change in window and level settings. The potential clinical uses for such an algorithm are described in a pictorial overview, including applications in emergency radiology, oncologic imaging, and nuclear medicine and molecular imaging.

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Correspondence to Jacob C. Mandell.

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Les R. Folio is an associate investigator in a research agreement with Carestream Health (Rochester, NY).

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Mandell, J.C., Khurana, B., Folio, L.R. et al. Clinical Applications of a CT Window Blending Algorithm: RADIO (Relative Attenuation-Dependent Image Overlay). J Digit Imaging 30, 358–368 (2017).

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  • CT window settings
  • Grayscale visualization
  • Contrast sensitivity
  • CT dynamic range