Abstract
Stereotactic body radiotherapy (SBRT) is an innovative irradiation technique which delivers high dose per fraction in a highly accurate way. It allows to treat medically inoperable patients with non-small cell lung cancer, with impressive local control rates and a very little toxicity. The different SBRT techniques available are presented in this article. Results from literature studies of SBRT for stage I non-small cell lung cancer are reviewed.
Résumé
La radiothérapie en conditions stéréotaxiques (RTCS) extra-crânienne est une technique innovante en radiothérapie qui délivre de fortes doses par fractions avec une précision millimétrique. Cette technique permet de traiter avec un fort taux de contrôle local et une toxicité modérée des patients porteurs de cancer bronchique non à petites cellulesmédicalement inopérables. Après avoir décrit les différentes techniques de RTCS, cet article présente une revue de la littérature des résultats de la RTCS appliquée aux cancers bronchiques de stade I.
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Références
Baba F, Shibamoto Y, Ogino H, et al. (2010) Clinical outcomes os stereotactic body radiotherapy for stage I non-small cell lung cancer unsig different doses depending on tumor size. Radiat Oncol 5: 81–88
Bauman P, Nyman J Hoyer M, et al. (2009) Outcome in a prospective phase II trial of medically inoperable stage I non-small-cell lung cancer patients treated with stereotactic body radiotherapy. J Clin Oncol 27: 3290–3296
Fakiris AJ, McGarry RC, Yiannoutsos CT, et al. (2009) Stereotactic body radiation therapy for early stage non-small cell lung carcinoma: four-year results of a prospective phase II study. Int J Radiat Oncol Biol Phys 75: 677–82
Fritz P, Kraus HJ, Muhlnickel W, et al. (2006) Stereotactic, sigle dose irradiation of stage I non small cell lung cancer and lung metastases. Radiat Oncol 1: 30
Grills I, Mangona V, Welsh R, et al. (2010) Outcomes After Stereotactic Lung Radiotherapy or Wedge Resection for Stage I Non-Small-Cell Lung Cancer. J Clin Oncol; 28: 928–935
Grutters J, Kessels A, Pijls-Johannesma M, et al. (2010) Comparison of effectiveness of radiotherapy with photons, protons and carbon-ions for non-small cell lung cancer: a meta-analysis. Radiother Oncol 95: 32–40
Hara R, Itami J, Kondo T, et al. (2006) Clinical outcomes of single-fraction stereotactic radiation therapy for lung tumors. Cancer 106: 1347–1352
Heinzerling J, Kavanagh B, Timmerman R (2011) Stereotactic ablative radiation therapy for primary lung tumors. Cancer J 17: 28–32
Jeremic B, Classen J, Bamberg M (2002) Radiotherapy alone in technically operable, medically inoperable, early stages (I/II) non small cell lung cancer. Int J Radiat Oncol Biol Phys 54: 119–130
Lagerwaard FJ, Haasbeek CJ, Smit EF, et al. (2008) Outcomes of risk-adapted fractionated stereotactic radiotherapy for stage I non-small cell lung cancer Int J Radiat Oncol Biol Phys 70: 685–692
Leskell L (1951) The stereotactic method and radiosurgery of the brain. Acta Chir Scand 102: 316–319
Mutter R, Liu F, Abreu A, et al. (2011) Dose-volume parameters predict for the development of chest wall pain after stereotxtic body radiation for lung cancer. Int J Radiat Oncol Biol Phys, in press
Nagata Y, Takayama K, Matsuo Y, et al. (2005) Clinical outcomes of a phase I/II study of 48 Gy of stereotactic body radiotherapy for primary lung cancer using a stereotactic bodyframe. Int J Radiat Oncol Biol Phys 63: 1427–431
Olsen, JR, Robinson CG, El Naqa I, et al. (2011) Response for Stereotactic body radiotherapy in early-stage non-small cell lung cancer. Int J Radiat oncol Biol Phys 81: e299–e303
Ong C, Palma D, Vebakel W, et al. (2010) Treatment of large stage I–II lung tumours using stereotactic body radiotherapy (SBRT): planning considerations and early toxicity. Radiother Oncol 97: 431–436
Onishi H, Nagata S, Hiraoka M, et al. (2011) When is SBRT best? J Thorac Oncol 6: S262
Onishi H, Shirato H, Nagata Y, et al. (2007) Hypofractionated Sterotactic Radiotherapy for stage I non-small cell lung cancer: updated results of 257 patients in a japanese multi-institutional study. J Thorac Oncol 2: S94–S100
Ricardi U, Filippi AR, Guarneri A, et al. (2010) Stereotactic body radiation therapy for early stage non-small cell lung cancer: results of a prospective trial. Lung Cancer 68: 72–77
Shibamoto y, Hashizume C, Baba F, et al. (2011) Streotactic body radiotherapy using a radiobiology-based regimen for stage I nonsmall cell lung cancer. Cancer, in press
Sibley GS (1998) Radiotherapy for patients with medically inoperable Stage I nonsmall cell lung carcinoma: smaller volumes and higher doses — a review. Cancer 82: 433–438
Stephans KL, Djemil T, Reddy CA, et al. (2009) A comparison of two stereotactic body radiation fractionation schedules for medically inoperable stage I nonsmall cell lung cancer: the Cleveland Clinic Experience. J Thorac Oncol 4: 976–982
Taremi M, Hope A, Dahele M, et al. (2011) Stereotactic body radiotherapy for medically inoperable lung cancer: prospective, single-center study of 108 consecutive patients. Int J Radiat Oncol Biol Phys, in press
Timmerman R (2008) An overview of hypofractionation and introdiction to this issue of Seminars in Radiation Oncology. Rad Oncol 18(4): 215–222
Timmerman R, McGarry R, Yiannoutsos C, et al. (2006) Excessive toxicity when treating central tumors in a phase II study of stereotactic body radiation therapy for medically inoperable early stage lung cancer. J Clin Oncol 24: 4833–4839
Timmerman R, Paulus R, Galvin J, et al. (2010) Stereotactic body radiation therapy for inoperable early stage lung cancer JAMA 303: 1070–1076
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Martel-Lafay, I. Radiothérapie en conditions stéréotaxiques des cancers bronchiques de stade I. Oncologie 14, 282–288 (2012). https://doi.org/10.1007/s10269-012-2154-9
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DOI: https://doi.org/10.1007/s10269-012-2154-9