Abstract
Managementof haematological malignancies in the elderly needs more attention than in younger patients. While some of them can be proposed standard therapy with specific precautions such as colony-stimulating factors, a significant part of them needs a more thorough evaluation with geriatric instruments. The so-called comprehensive geriatric assessment (CGA) is necessary to indicate geriatric interventions. Vulnerable and frail patients will benefit from this approach to better equilibrate the risk/benefit ratio, which may be highly unstable. However, this approach is time-consuming, and screening techniques are being developed. Such questionnaires will be available soon.
Résumé
La prise en charge des patients âgés atteints d’hémopathie maligne nécessite une attention plus particulière que pour le sujet jeune. Si nombre d’entre eux peuvent être traités de façon standard avec seulement quelques précautions de type facteurs de croissance hématopoïétiques, d’autres nécessitent une évaluation plus attentive nécessitant une approche gériatrique. Cette évaluation, dite évaluation gériatrique standardisée (EGS), est nécessaire pour poser l’indication d’interventions gériatriques. Les patients dits vulnérables ou fragiles doivent bénéficier de cette approche renforcée pour équilibrer au mieux la balance bénéfice/risque, hautement sensible chez eux. Cependant, elle reste une méthode coûteuse en temps humain, et des méthodes de dépistage sont en cours d’élaboration et devraient être rapidement disponibles.
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Soubeyran, P., Bellera, C. & Rainfray, M. Évaluation gériatrique dans les hémopathies lymphoïdes. Oncologie 13, 589–594 (2011). https://doi.org/10.1007/s10269-011-2072-2
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DOI: https://doi.org/10.1007/s10269-011-2072-2