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De la radiothérapie conventionnelle á l’utilisation de la robotique: des évolutions technologiques et une révolution des pratiques

From conventional radiation therapy to robotic approach: technological evolution and revolution of practice

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Oncologie

Abstract

Since the discovery of X-ray by Röntgen in 1895, the technological evolution of radiation therapy increased swiftly. However, the philosophy remained always the same: delivering higher radiation dose to the target volume while decreasing the dose to the organ at risk. Since the beginning of the 1990s, with conformal radiation therapy development (3DCT), differents techniques appeared. Some of them are derived from 3DCT, such as intensity-modulated radiation therapy, arctherapy, Tomotherapy™, or techniques using gating approach for breath holding. In the frame of stereotactic radiation therapy, the GammaKnife™ is already used since 20 years, while new concepts, based on a robotic approach (CyberKnife™), are now available for treatment. Brachytherapy also took advantage from the technological evolution with the new approaches. In the frame of heavy ions, hadrontherapy represents an interesting technique dedicated to special clinical situations including pediatric tumors. In this article, we report an analysis of the technological evolution of radiation therapy.

Résumé

Depuis la découverte des rayons X(RX) par Röntgen, en 1895, á nos jours, l’évolution technologique de la radiothérapie n’a cessé de s’accélérer. Cependant, la philosophie est toujours restée la même: délivrer une forte dose au volume cible tout en limitant la dose aux organes á risque. Depuis le début des années 1990, avec l’aveènement de la radiothérapie conformationnelle (RC3D), différentes techniques se sont développées. Certaines sont dérivées de la RC3D comme la RC3D avec modulation d’intensité, l’arcthérapie, la Tomothérapie™ ou les techniques d’asservissement respiratoire. Dans le domaine de la radiothérapie stéréotaxique, le GammaKnife™ est utilisé depuis une vingtaine d’annes, alors que de nouveaux concepts basés sur une approche robotique de l’irradiation (CyberKnife™) sont á présent utilisés. Aux côtés de la radiothérapie externe, la curiethérapie de nouvelle génération a, elle aussi, pu bénéficier de progrès technologiques majeurs. Dans le domaine des ions lourds, l’hadronthérapie représente une technique adaptée á des situations cliniques complexes, notamment en pédiatrie. Nous présentons ici une analyse de l’évolution technologique de la radiothérapie.

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Références

  1. Aird EG (1989) Radiotherapy today and tomorrow: an introduction to optimisation of conformal radiotherapy. Phys Med Biol 34(10): 1345–1348

    Article  CAS  PubMed  Google Scholar 

  2. Cao D, Afghan MK, Ye J, et al. (2009) A generalized inverse planning tool for volumetric-modulated arctherapy. Phys Med Biol 54(21): 6725–6738

    Article  PubMed  Google Scholar 

  3. Chang Z, Wang Z, Wu QJ, et al. (2008) Dosimetric characteristics of Novalis™ Tx system with high-definition multileaf collimator. Med Phys 35(10): 4460–4463 (http://www.cyberknife.com/)

    Article  PubMed  Google Scholar 

  4. Dinka D, Nyce JM, Timpka T (2005) GammaKnife™ surgery: safety and the identity of users. Technol Health Care 13(6): 485–495

    PubMed  Google Scholar 

  5. Dutreix J, Dutreix A, Bernard M (1962) Study of the dose in the vicinity of the interface between 2 media of different atomic composition exposed to gamma radiation from cobalt-60. Phys Med Biol 7: 69–82

    Article  CAS  PubMed  Google Scholar 

  6. Elekta VMAT. Conformance. Speed. Ultra-low dose. http://www.elekta.com/healthcare_us_elekta_vmat.php

  7. GammaKnife™ Center. http://www.upstate.edu/uh/gamma/

  8. Gifford KA, Price MJ, Horton JL Jr, et al. (2008) Optimization of deterministic transport parameters for the calculation of the dose distribution around a high dose-rate 192Ir brachytherapy source. Med Phys 35(6): 2279–2285

    Article  CAS  PubMed  Google Scholar 

  9. http://www.cyberknife.com/

  10. Kawachi T, Saitoh H, Inoue M, et al. (2008) Reference dosimetry condition and beam quality correction factor for CyberKnife™ beam. Med Phys 35(10): 4591–4598

    Article  PubMed  Google Scholar 

  11. La situation du cancer en France (2007) Rapport Institut national du cancer: 31–32

  12. Mesures nationales pour la radiothérapie (2007) Travail collectif des missions Institut national du cancer (INCa), Autoritéde sûreté nucléaire (ASN), Agence française de sécurité sanitaire des produits de santé (Afssaps), Institut de veille sanitaire (InVS), Société française de radiothérapie oncologique (SFRO) 14–15

  13. Pierquin B, Chassagne D (1962) The non-radioactive preparation in interstitial and contact curietherapy. J Radiol Electrol Med Nucl 43: 65–68

    CAS  PubMed  Google Scholar 

  14. Pierquin B, Perez R, Dutreix A (1959) Technical presentation and dosimetry of cobalt-60 pearls. J Radiol Electrol Med Nucl 40: 687–690

    CAS  PubMed  Google Scholar 

  15. Sterzing F, Kalz J, Sroka-Perez G, et al. (2009) Megavoltage CT in helical tomotherapy clinical advantages and limitations of special physical characteristics. Technol Cancer Res Treat 8(5): 343–352

    PubMed  Google Scholar 

  16. Survie des patients atteints de cancer en France (2007) Étude des registres du réseau Francim

  17. Tait D, Nahum A, Southall C, et al. (1988) Benefits expected from simple conformal radiotherapy in the treatment of pelvic tumors. Radiother Oncol 13(1): 23–30

    Article  CAS  PubMed  Google Scholar 

  18. Tomotherapy. http://www.tomotherapy.com/

  19. Varian medical systems. Oncology treatment solutions. http://www.varian.com/us/oncology/treatments/treatment_techniques/rapidarc/

  20. Webb S (1992) Optimization by simulated annealing of three-dimensional, conformal treatment planning for radiation fields defined by a multileaf collimator: II. Inclusion of two-dimensional modulation of the X-ray intensity. Phys Med Biol 37(8): 1689–704

    Article  CAS  PubMed  Google Scholar 

  21. Webb S, McQuaid D (2009) Some considerations concerning volume-modulated arctherapy: a stepping stone towards a general theory. Phys Med Biol 54(14): 4345–4360

    Article  CAS  PubMed  Google Scholar 

  22. Xu Q, He Z, Fan J, et al. (2009) Registration of on-board X-ray images with 4DCT: a proposed method of phase and setup verification for gated radiotherapy. Phys Med (in press)

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Correspondence to J. -M. Hannoun-Levi.

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Association de radiothérapie et d’oncologie de la méditerranée (Arome; www.aromecancer.org

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Hannoun-Levi, J.M., Lartigau, E. & Belkacémi, Y. De la radiothérapie conventionnelle á l’utilisation de la robotique: des évolutions technologiques et une révolution des pratiques. Oncologie 12, 60–64 (2010). https://doi.org/10.1007/s10269-009-1828-4

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