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Ice cube stimulation helps to improve dysgeusia

Abstract

Dysgeusia causes a decrease in appetite, and it is one of the major factors in undernutrition. Dysgeusia is elicited by numerous causes, and in many cases it is still difficult to treat the various symptoms complained of by patients. We herein report a case in which dysgeusia was improved by transient cooling of the mouth.

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References

  1. 1.

    Perez CA, Huang L, Rong M, Kozak JA, Preuss AK, Zhang H, Max M, Margolskee F. A transient receptor potential channel expressed in taste receptor cells. Nat Neurosci 2002;5:1169–1176.

    Article  PubMed  Google Scholar 

  2. 2.

    Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJP. Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. Cell 2003;112:293–301.

    Article  PubMed  Google Scholar 

  3. 3.

    Talavera K, Yasumatsu K, Voets T, Droogmans G, Shigemura N, Ninomiya Y, Margolskee RF, Nilius B. Heat activation of TRPM5 underlies thermal sensitivity of sweet taste. Nature 2005;438:1022–1025.

    Article  PubMed  Google Scholar 

  4. 4.

    Talavera K, Ninomiya Y, Winkel C, Voets T, Nilius B. Visions and reflections (minireview). Influence of temperature on taste perception. Cell Mol Life Sci 2007;64:377–381.

    Article  PubMed  Google Scholar 

  5. 5.

    Lu SH, Dai YT, Yen CJ. The effects of measurement site and ambient temperature on body temperature values in healthy older adults: a cross-sectional comparative study. Int J Nurs Stud 2009;46:1415–1422.

    Article  PubMed  Google Scholar 

  6. 6.

    Hellekant G. The effects of changes in the blood flow to the tongue on the chorda tympani response in rat. Acta Physiol Scand 1971;82:145–153.

    Article  PubMed  Google Scholar 

  7. 7.

    Lazzara G, Lazarus C, Logemann JA. Impact of thermal stimulation on the triggering of the swallowing reflex. Dysphagia 1986;1:73–77.

    Article  Google Scholar 

  8. 8.

    Kaatzke-McDonald MN, Post E, Davis PJ. The effects of cold, touch, and chemical stimulation of the anterior facial pillar on human swallowing. Dysphagia 1996;11:198–206.

    Article  PubMed  Google Scholar 

  9. 9.

    Voets T, Talavera K, Owsianik G, Nilius B. Sensing with TRP channels. Nat Chem Biol 2005;1:85–92.

    Article  PubMed  Google Scholar 

  10. 10.

    Bautista DM, Siemens J, Glazer JM, Tsuruda PR, Basbaum AI, Stucky CL, Jordt SE, Julius E. The menthol receptor TRPM8 is the principal detector of environmental cold. Nature 2007;448:204–209.

    Article  PubMed  Google Scholar 

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Correspondence to Rie Fujiyama.

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Fujiyama, R., Ishitobi, S., Honda, K. et al. Ice cube stimulation helps to improve dysgeusia. Odontology 98, 82–84 (2010). https://doi.org/10.1007/s10266-009-0110-y

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Key words

  • Dysgeusia
  • Cold stimulation
  • Taste receptors