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Arterite di Horton: è sempre necessaria la biopsia dell’arteria temporale?

Is temporal artery biopsy always necessary in temporal arteritis?

Abstract

Temporal arteritis is the most common form of systemic vasculitis affecting elderly persons. The disease is considered a medical emergency, with potentially severe ophthalmic complications such as rapidly progressive irreversible visual loss. A prompt diagnosis and an immediate pharmacologic treatment are mandatory in order to prevent these complications. At present temporal artery biopsy is considered the diagnostic “gold standard” but new evidences support the role of ultrasonography as a non-invasive approach for the diagnosis of the disease. Recent advances in technologic equipment, together with skilled operators, will contribute to support the role of this approach in the diagnosis, follow-up and prevention of subsequent flares of the disease after treatment withdrawal. Further studies to assess the test performance in these settings are warranted.

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Bibliografia

  1. Horton BT, Magath BT, Brown GE (1937) Arteritis of temporal vessels: report of 7 cases. Proc Staff Meet Mayo Clin 12:548–553

    Google Scholar 

  2. Jennings GH (1938) Arteritis of the temporal vessels. Lancet 1:424

    Article  Google Scholar 

  3. Smith CA, Fidler WJ, Pinals RS (1983) The epidemiology of giant cell arteritis. Report of a ten-year study in Shelby County, Tennessee. Arthritis Rheum 26:1214–1219

    CAS  Article  PubMed  Google Scholar 

  4. Boesen P, Sørensen SF (1987) Giant cell arteritis, temporal arteritis, and polymyalgia rheumatica in a Danish county. A prospective investigation, 1982–1985. Arthritis Rheum 30:294–299

    CAS  Article  PubMed  Google Scholar 

  5. Salvarani C, Gabriel SE, O’Fallon WM, Hunder GG (1995) The incidence of giant cell arteritis in Olmsted County, Minnesota: apparent fluctuations in a cyclic pattern. Ann Intern Med 123:192–194

    CAS  PubMed  Google Scholar 

  6. Kobayashi S, Yano T, Matsumoto Y et al (2003) Clinical and epidemiologic analysis of giant cell (temporal) arteritis from a nationwide survey in 1998 in Japan: the first government-supported nationwide survey. Arthritis Rheum 49:594–598

    Article  PubMed  Google Scholar 

  7. Salvarani C, Macchioni P, Zizzi F et al (1991) Epidemiologic and immunogenetic aspects of polymyalgia rheumatica and giant cell arteritis in northern Italy. Arthritis Rheum 34:351–356

    CAS  Article  PubMed  Google Scholar 

  8. Salvarani C, Crowson CS, O’-Fallon WM et al (2004) Reappraisal of the epidemiology of giant cell arteritis in Olmsted County, Minnesota, over a fiftyyear period. Arthritis Rheum 51:264–268

    Article  PubMed  Google Scholar 

  9. Hunder GG, Bloch DA, Michel BA et al (1990) The American College of Rheumatology 1990 criteria for the classification of giant cell arteritis. Arthritis Rheum 33:1122–1128

    CAS  Article  PubMed  Google Scholar 

  10. Devauchelle-Pensec V, Jousse S, Destombe C, Saraux A (2008) Epidemiology, imaging and treatment of giant cell arteritis. Joint Bone Spine 75:267–272

    Article  PubMed  Google Scholar 

  11. Hu Z, Yang Q, Zeng S et al (2002) Giant cell arteritis in China: a prospective investigation. Angiology 53:457–463

    Article  PubMed  Google Scholar 

  12. Wang X, Hu ZP, Lu W et al (2008) Giant cell arteritis. Rheumatol Int 29:1–7

    Article  PubMed  Google Scholar 

  13. Rahman W, Rahman FZ (2005) Giant cell (temporal) arteritis: an overview and update. Surv Ophthalmol 50:415–428

    Article  PubMed  Google Scholar 

  14. Weyand CM, Bartley GB (1997) Giant cell arteritis: new concepts in pathogenesis and implications for management. Am J Ophthalmol 123:392–395

    CAS  PubMed  Google Scholar 

  15. Navarro M, Cervera R, Font J et al (1997) Anti-endothelial cell antibodies in systemic autoimmune diseases: prevalence and clinical significance. Lupus 6:521–526

    CAS  Article  PubMed  Google Scholar 

  16. Gonzalez-Gay MA (2005) The diagnosis and management of patients with giant cell arteritis. J Rheumatol 32:1186–1188

    PubMed  Google Scholar 

  17. Narváez J, Bernad B, Roig-Vilaseca D et al (2007) Influence of previous corticosteroid therapy on temporal artery biopsy yield in giant cell arteritis. Semin Arthritis Rheum 37:13–19

    Article  PubMed  Google Scholar 

  18. Hayreh SS, Podhajsky PA, Raman R, Zimmerman B (1997) Giant cell arteritis: validity and reliability of various diagnostic criteria. Am J Ophthalmol 123:285–296

    CAS  PubMed  Google Scholar 

  19. Bhatti MT, Goldstein MH (2001) Facial nerve injury following superficial temporal artery biopsy. Dermatol Surg 27:15–17

    CAS  Article  PubMed  Google Scholar 

  20. Mizen TR (1991) Giant cell arteritis: diagnostic and therapeutic considerations. Ophthalmol Clin North Am 4:547–556

    Google Scholar 

  21. Kelley JS (1978) Doppler ultrasound flow detector used in temporal artery biopsy. Arch Ophthalmol 96:845–846

    CAS  PubMed  Google Scholar 

  22. Dany F, Liozon F, Chaumont P et al (1989) Sensibilité et specificité du Doppler temporal dans la maladie de Horton. J Mal Vasc 14[Suppl. C]:104–108

    PubMed  Google Scholar 

  23. Vinckier L, Hatron PY, Gadenne C et al (1989) Intérêt du Doppler arteriel dans la maladie de Horton. J Mal Vasc 14[Suppl. C]:116–122

    PubMed  Google Scholar 

  24. Puéchal X, Chauveau M, Menkès CJ (1995) Temporal Doppler-flow studies for suspected giant-cell arteritis. Lancet 345:1437–1438

    Article  PubMed  Google Scholar 

  25. Schmidt WA, Kraft HE, Vorpahl K et al (1997) Color duplex ultrasonography in the diagnosis of temporal arteritis. N Engl J Med 337:1336–1342

    CAS  Article  PubMed  Google Scholar 

  26. Salvarani C, Silingardi M, Ghirarduzzi A et al (2002) Is duplex ultrasonography useful for the diagnosis of giant-cell arteritis? Ann Intern Med 137:232–238

    PubMed  Google Scholar 

  27. Karassa FB, Matsagas MI, Schmidt WA, Ioannidis JP (2005) Meta-analysis: test performance of ultrasonography for giant-cell arteritis. Ann Intern Med 142:359–369

    PubMed  Google Scholar 

  28. Karahaliou M, Vaiopoulos G, Papaspyrou S et al (2006) Colour duplex sonography of temporal arteries before decision for biopsy: a prospective study in 55 patients with suspected giant cell arteritis. Arthritis Res Ther 8:R116

    Article  PubMed  Google Scholar 

  29. Bley TA, Wieben O, Uhl M et al (2005) High-resolution MRI in giant cell arteritis: imaging of the wall of the superficial temporal artery. AJR Am J Roentgenol 184:283–287

    PubMed  Google Scholar 

  30. Blockmans D, de Ceuninck L, Vanderschueren S et al (2006) Repetitive 18F-fluorodeoxyglucose positron emission tomography in giant cell arteritis: a prospective study of 35 patients. Arthritis Rheum 55:131–137

    Article  PubMed  Google Scholar 

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Sinigaglia, L., Casari, S. & Di Luca, G. Arterite di Horton: è sempre necessaria la biopsia dell’arteria temporale?. Arch Ortop Reumatol 121, 23–25 (2010). https://doi.org/10.1007/s10261-010-0011-1

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  • DOI: https://doi.org/10.1007/s10261-010-0011-1