Skip to main content
Log in

Significance of entropy generation and heat source: the case of peristaltic blood flow through a ciliated tube conveying Cu-Ag nanoparticles using Phan-Thien-Tanner model

  • Original Paper
  • Published:
Biomechanics and Modeling in Mechanobiology Aims and scope Submit manuscript

Abstract

The present speculative investigation is concentrated to analyze the entropy generation and heat transfer phenomena in ciliary induced peristalsis of blood with the suspension of hybrid nanoparticles in a tube with heat source impact. The blood is assumed to contain copper (Cu) and silver (Ag) nanoparticles (NPs). The ciliary inner wall of the tube has been considered with small hair-like structures. The Phan-Thien-Tanner (PTT) fluid model is employed to describe the non-Newtonian rheological characteristics of blood. The conservative equations are normalized and simplified by utilizing scaling analysis with the assumption of low Reynolds number and large wavelength approximations. The analytical inspection exposes that the total entropy generation gets a decrement for mounting values of cilia length, while reversed impact is detected for an increment in heat source parameter. Hybrid nano-blood exhibits a greater total entropy number than mono nano-blood. This research study may be beneficial to medical experts and researchers in the field of embryology. Cysts in the ciliated fallopian tube, where embryos develop, are removed by using nanoparticles (nano-drug delivery).

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10

Similar content being viewed by others

Abbreviations

\(\tilde{a}\) :

Mean radius of tube

Be :

Bejan number

Br :

Brinkman number

c :

Metachronal wave speed

\(C_{\text{p}}\) :

Specific heat

\(E_{\text{g}}\) :

Characteristic entropy generation rate

F :

Mean flow rate

h :

Ciliated wall

k :

Thermal conductivity

\(N_{\text{S}}\) :

Non-dimensional entropy generation rate

\(\tilde{P}\) :

Pressure in the laboratory frame

p :

Pressure in wave frame

Q :

Volume flow rate

\(Q_0\) :

Internal heat source coefficient

Re :

Reynolds number

t :

Non-dimensional time parameter

\(\tilde{t}\) :

Dimensional time parameter

\(\tilde{T}\) :

Blood temperature

\(\tilde{T}_0\) :

Temperature at tube wall

(uw):

Non-dimensional velocity components in (rz)

\((\tilde{u}, \tilde{w})\) :

Moving frame velocity components in \((\tilde{r} ,\tilde{z})\)

\((\tilde{U},\tilde{W})\) :

Fixed frame velocity components in \((\tilde{R} ,\tilde{Z})\)

We :

Weissenberg number

\(\tilde{Z}_0\) :

Reference particle position

\(Z^*\) :

Heat transfer coefficient

\(\alpha\) :

Eccentricity due to elliptical movement

\(\beta\) :

Wave number

\(\delta\) :

Dimensional cilia length

\(\gamma\) :

Heat source parameter

\(\lambda\) :

Metachronal wavelength

\(\Lambda\) :

Relaxation time

\(\mu\) :

Constant viscosity coefficient

\((\phi _1, \phi _2)\) :

Solid Volume fractions of Cu and Ag-NPs

\(\psi\) :

Stream function

\(\rho\) :

Blood density

\(\tilde{\tau }\) :

Extra stress tensor

\(\tau _{ij}\) :

Component of stress tensor

\(\theta\) :

Non-dimensional blood temperature

\(\tilde{\theta }_0\) :

Temperature difference

\(\varepsilon\) :

Elongation parameter

\(\zeta\) :

Temperature difference parameter

\(s_1\) :

Copper nanoparticles (Cu-NPs)

\(s_2\) :

Silver nanoparticles (Ag-NPs)

f :

Base fluid (blood)

nf :

Cu-blood nanofluid

hnf :

Cu-Ag/blood hybrid nanofluid

References

  • Abdelsalam SI, Vafai K (2017) Particulate suspension effect on peristaltically induced unsteady pulsatile flow in a narrow artery: blood flow model. Math Biosci 283:91–105

    MathSciNet  MATH  Google Scholar 

  • Abdelsalam SI, Mekheimer KS, Zaher AZ (2020) Alterations in blood stream by electroosmotic forces of hybrid nanofluid through diseased artery: Aneurysmal/stenosed segment. Chin J Phys 67:314–329

    MathSciNet  Google Scholar 

  • Abo-Dahab SM, Abdelhafez MA, Mebarek-Oudina F, Bilal SM (2021) MHD Casson nanofluid flow over nonlinearly heated porous medium in presence of extending surface effect with suction/injection. Indian J Phys 2021. https://doi.org/10.1007/s12648-020-01923-z

  • Abrar MM, Sagheer M, Hussian S (2020) Thermodynamics analysis of Joule heating and internal heat source over an inclined ciliated tube. Physica A 549:123983

    MathSciNet  Google Scholar 

  • Adesanya SO, Makinde OD (2015) Thermodynamic analysis for a third-grade fluid through a vertical channel with internal heat generation. J Hydrodyn 27:264–272

    Google Scholar 

  • Agrawal HL, Anawaruddin, (1984) Cilia transport of bio-fluid with variable viscosity. Indian J Pure Appl Math 10:1128–1139

  • Akbar NS (2015) Entropy generation and energy conversion rate for the peristaltic flow in a tube with magnetic field. Energy 82:23–30

    Google Scholar 

  • Akbar NS, Butt AW (2014) Heat transfer analysis of viscoelastic fluid flow due to metachronal wave of cilia. Int J Biomathematics 7(6):1450066

    MathSciNet  MATH  Google Scholar 

  • Akbar NS, Nadeem S (2012) Peristaltic flow of a Phan-Thien-Tanner nanofluid in a diverging tube. Heat Transf Res 41(1):10–22

    Google Scholar 

  • Ali A, Banerjee SM, Das S (2021) Hall and ion slip currents impact on magneto-sodium alginate hybrid nanoliquid past a moving vertical plate with ramped heating, velocity slip and Darcy effects. Multidiscip Model Mater Struct 17(1):65–101

    Google Scholar 

  • Bejan A (1979) A study of entropy generation in fundamental convective heat transfer. J Heat Transf 101:718–725

    Google Scholar 

  • Bejan A (1982) Second-law analysis in heat transfer and thermal design. Adv Heat Transf 15:1–58

    Google Scholar 

  • Blake JR (1971) A spherical envelope approach to ciliary propulsion. J Fluid Mech 46(1):199–208

    MathSciNet  MATH  Google Scholar 

  • Blake JR (1972) A model for the micro-structure in ciliated organisms. J Fluid Mech 55(1):1–23

    MathSciNet  MATH  Google Scholar 

  • Brennen C (1974) Oscillating-boundary layer theory for ciliary propulsion. J Fluid Mech 65:799–824

    MATH  Google Scholar 

  • Bustamante-Marin XM, Ostrowski LE (2017) Cilia and mucociliary clearance. Cold Spring Harb Perspect Biol 4:a028241

    Google Scholar 

  • Butt AS, Ali A, Munawar S (2013) Slip effects on entropy generation in MHD flow over a stretching surface in the presence of thermal radiation. Int J Exergy 13:1–20

    Google Scholar 

  • Butt AW, Akbar NS, Mir NA (2020) Heat transfer analysis of peristaltic flow of a Phan-Thien-Tanner fluid model due to metachronal wave of cilia. Biomech Model Mechanobiol 19:1925–1933

    Google Scholar 

  • Chamkha AJ, Selimefendigil F (2018) MHD free convection and entropy generation in a corrugated cavity filled with a porous medium saturated with nanofluids. Entropy 20:846

    Google Scholar 

  • Choi SUS (1995) Enhancing thermal conductivity of fluids with nanoparticles. In: Siginer DA, Wang HP(Eds.) Developments and applications of non-Newtonian flows, FED-vol. 231/MD-66, ASME, New York, pp 99-105

  • Das S, Ali A, Jana RN (2020) Darcian slip flow of rotating magneto-reactive PEG conveying MoS\(_2\) Casson nanofluid with ramped temperature and concentration. Spec Top Rev Porous Media 11:71–102

  • Drummond IA (2012) Cilia functions in development. Curr Opin Cell Biol 1:24–30

    Google Scholar 

  • Eddy CA, Pauerstein CJ (1980) Anatomy and physiology of the fallopian tube. Clin Obstet Gynecol 4:1177–1193

    Google Scholar 

  • El Naby AEHA (2009) Creeping flow of Phan-Thien-Tanner fluids in a peristaltic tube with an infinite long wavelength. J Appl Mech 76(6):064504

    Google Scholar 

  • Ellahi R, Sait SM, Shehzad N, Ayaz Z (2020) A hybrid investigation on numerical and analytical solutions of electro-magnetohydrodynamics flow of nanofluid through porous media with entropy generation. Int J Numer Method Heat Fluid Flow 30:834–854

    Google Scholar 

  • Elnaqeeb T, Animasaun IL, Shah MA (2021) Ternary-hybrid nanofluids: significance of suction and dual-stretching on three-dimensional flow of water conveying nanoparticles with various shapes and densities. Zeitschrift Fuür Naturforschung A 76(3):231–243

    Google Scholar 

  • Fares R, Mebarek-Oudina F, Aissa A, Bilal SM, Öztop HF (2021) Optimal Entropy Generation in Darcy-Forchheimer Magnetized Flow in a Square Enclosure Filled with Silver Based Water Nanoliquid. J Therm Anal Calorim. https://doi.org/10.1007/s10973-020-10518-z

    Article  Google Scholar 

  • Farooq AA, Siddiqui AM (2017) Mathematical model for the ciliary-induced transport of seminal liquids through the ductuli efferentes. Int J Biomath 10:1750031

    MathSciNet  MATH  Google Scholar 

  • Farooq AA, Tripathi D, Elnaqeeb T (2019) On the propulsion of micropolar fluid inside a channel due to ciliary induced metachronal wave. Appl Math Comput 347:225–235

    MathSciNet  MATH  Google Scholar 

  • Ghazal S, Makarov JK, de Jonge CJ (2014) Egg transport and fertilization. Glob Libr Women Med 2014. https://doi.org/10.3843/GLOWM.10317

  • Hanasoge S, Ballard MR, Hesketh PJ, Alexeev A (2017) Asymmetric motion of magnetically actuated artificial cilia. Lab Chip 17:3138–3145

    Google Scholar 

  • Hayat T, Noreen S, Ali N, Abbasbanday S (2012) Peristaltic motion of Phan-Thien-Tanner fluid in a planar channel. Numer Method Partial Differ Equ 28:737–748

    MathSciNet  Google Scholar 

  • Hayat T, Aslam N, Rafiq M, Alsaedi A (2017) Studying peristaltic transport of shape nanozise silver-water nanoparticles in digestive system with heat generation effect. Int J Heat Mass transf 106:18–24

    Google Scholar 

  • Husband B, Bu M, Apostolopoulos V, Melvin T, Evans A (2004) Novel actuation of an integrated peristaltic micropump. Microelectron Eng 73:858–863

    Google Scholar 

  • Ijaz S, Nadeem S (2018) Shape factor and sphericity features examination of Cu and Cu-Al2O3 / blood through atherosclerotic artery under the impact of wall characteristic. J Mol Liq 271:361–372

    Google Scholar 

  • Ijaz S, Iqbal Z, Maraj EN, Nadeem S (2018) Investigate of Cu-CuO / blood mediated transportation in stenosed artery with unique features for theoretical outcomes of hemodynamics. J Mol Liq 254:421–432

    Google Scholar 

  • Knowles MR, Boucher RC (2002) Mucus clearance as a primary innate defense mechanism for mammalian airways. J Clin Investig 109:571–577

    Google Scholar 

  • Koriko OK, Adegbie KS, Shah NA, Animasaun IL, Olotu MA (2021) Numerical solutions of the partial differential equations for investigating the significance of partial slip due to lateral velocity and viscous dissipation: The case of blood-gold Carreau nanofluid and dusty fluid. Numer Method Partial Differ Equ 1–29. https://doi.org/10.1002/num.22754

  • Latham TW (1966) Fluid Motion in a Peristaltic Pump [MS thesis]. Massachusetts Institute of Technology, Cambridge, MA

    Google Scholar 

  • Lehti MS, Sironen A (2017) Formation and function of sperm tail structures in association with sperm motility defects. Biol Reprod 97:522–536

    Google Scholar 

  • Makinde OD (2012) Entropy analysis for MHD boundary layer flow and heat transfer over a flat plate with a convective surface boundary condition. Int J Exergy 10:142–154

    Google Scholar 

  • Makinde OD, Reddy MG, Reddy KV (2017) Effects of thermal radiation on MHD peristaltic motion of Walters-B fluid with heat source and slip conditions. J Appl Fluid Mech 10(4):1105–1112

    Google Scholar 

  • Marzougui S, Bouabid M, Mebarek-Oudina F, Abu-Hamdeh N, Magherbi M, Ramesh K (2021) A computational analysis of heat transport irreversibility phenomenon in a magnetized porous channel. Int J Numer Method Heat Fluid Flow 31(7):2197–2222

    Google Scholar 

  • Mehmood OU, Qureshi AA, Yasmin H, Uddin S (2020) Thermo-mechanical analysis of non-Newtonian peristaltic mechanism: modified heat flux model. Phys A Statist Mech Its Appl 550:124014

    MathSciNet  Google Scholar 

  • Mills Z, Aziz B, Alexeev A (2012) Beating synthetic cilia enhance heat transport in microfluidic channels. Soft Matter 45:11508–11513

    Google Scholar 

  • Munawar S, Saleem N (2020) Entropy analysis of an MHD synthetic cilia assisted transport in a microchannel enclosure with velocity and thermal slippage effects. Coatings 10:414

    Google Scholar 

  • Munawar S, Saleem N, Aboura K (2016) Second law analysis in the peristaltic flow of variable viscosity fluid. Int J Exergy 20:170–185

    Google Scholar 

  • Oke AS, Animasaun IL, Mutuku WN, Kimathi M, Shah NA, Saleem S (2021) Significance of Coriolis force, volume fraction, and heat source/sink on the dynamics of water conveying 47 nm alumina nanoparticles over a uniform surface. Chin J Phys 71:716–727

    MathSciNet  Google Scholar 

  • Oliveira PJ, Pinho FT (1999) Analytical solution for fully developed channel and pipe flow of Phan-Thien-Tanner fluids. J Fluid Mech 387:271–280

    MathSciNet  MATH  Google Scholar 

  • Pablo JL, DeCaen PG, Clapham DE (2016) Progress in ciliary ion channel physiology. J Gen Physiol 1:37–41

    Google Scholar 

  • Phan-Thien N, Tanner RI (1977) A new constitutive equation derived from network theory. J. Non-Newtonian Fluid 2(4):353–365

    MATH  Google Scholar 

  • Phan-Thien N, Tanner RI (1978) A nonlinear network viscoelastic model. J Rheol 22(3):259–283

    MATH  Google Scholar 

  • Qiu T, Lee T, Mark AG, Morozov KI, Münster R, Mierka O, Turek S, Leshansky AM, Fischer P (2014) Swimming by reciprocal motion at low Reynolds number. Nat Commun 5:1–8

    Google Scholar 

  • Rajashekhar C, Mebarek-Oudina F, Vaidya H, Prasad KV, Manjunatha G, Balachandra H (2021) Mass and heat transport impact on the peristaltic flow of Ree-Eyring liquid with variable properties for hemodynamic flow. Heat Transf 2021. https://doi.org/10.1002/htj.22117

  • Reddy MG, Makinde OD (2016) Magnetohydrodynamic peristaltic transport of Jeffery nanofluid in an asymmetric channel. J Mol Liq 223:1242–1248

    Google Scholar 

  • Reddy MG, Prasannakumara BC, Makinde OD (2017) Cross diffusion impacts on hydromagnetic radiative peristaltic Carreau-Cassonnanofluids flow in an irregular channel. Defect Diffus Forum 377:62–83

    Google Scholar 

  • Sadaf H, Iftikhar N, Akbar NS (2019) Physiological fluid flow analysis by means of contraction and expansion with addition of hybrid nanoparticles. Eur Phys J Plus 134:232

    Google Scholar 

  • Saleem N (2018) Entropy production in peristaltic flow of a space dependent viscosity fluid in asymmetric channel. Therm Sci 22:2909–2918

    Google Scholar 

  • Saleem N, Munawar S (2020) Entropy analysis in cilia driven pumping flow of hyperbolic tangent fluid with magnetic field effects. Fluid Dyn Res 52:2

    MathSciNet  Google Scholar 

  • Saleem A, Akhtar S, Alharbi FM, Nadeem S, Ghalambaz M, Issakhov A (2020) Physical aspects of peristaltic flow of hybrid nano fluid inside a curved tube having ciliated wall. Res Phys 19:103431

    Google Scholar 

  • Sarkar J, Ghosh P, Adil A (2015) A review on hybrid nanofluids: recent research, development and applications. Renew Sustain Energy Rev 43:164–177

    Google Scholar 

  • Shah NA, Animasaun IL, Wakif A, Koriko OK, Sivaraj R, Adegbie KS, Abdelmalek Z, Vaidyaa H, Ijirimoye AF, Prasad KV (2020) Significance of suction and dual stretching on the dynamics of various hybrid nanofluids: Comparative analysis between type I and type II models. Phys Scr 95(9):095205

    Google Scholar 

  • Shahzadi I, Suleman S, Saleem S, Nadeem S (2020) Utilization of Cu-nanoparticles as medication agent to reduce atherosclerotic lesions of a bifurcated artery having compliant walls. Comput Methods Programs Biomed 184:105–123

    Google Scholar 

  • Song YQ, Obideyi BD, Shah NA, Animasaun IL, Mahrous YM, Chung JD (2021) Significance of haphazard motion and thermal migration of alumina and copper nanoparticles across the dynamics of water and ethylene glycol on a convectively heated surface. Case Stud Therm Eng 26:101050

    Google Scholar 

  • Souidi F, Ayachi K, Benyahia N (2009) Entropy generation rate for a peristaltic pump. J Non-Equilib Thermodyn 34:171–194

    MATH  Google Scholar 

  • Sowmya G, Gireesha BJ, Animasaun IL, Shah NA (2021) Significance of buoyancy and Lorentz forces on water-conveying iron(III) oxide and silver nanoparticles in a rectangular cavity mounted with two heated fins: heat transfer analysis. J Therm Anal Calorim 144:2369–2384

    Google Scholar 

  • Tamada LM, Janet A, Tierney MJ (2002) Keeping watch on glucose. IEEE Spectr 39(4):52–57

    Google Scholar 

  • Vaidya H, Rajashekhar C, Mebarek-Oudina F, Animasaun IL, Prasad KV, Makinde OD (2021a) Combined effects of homogeneous and heterogeneous reactions on peristalsis of Ree-Eyring liquid: application in hemodynamic flow. Heat Transf 50(3):2592–2609

    Google Scholar 

  • Vaidya H, Choudhari R, Prasad KV, Khan SU, Mebarek-Oudina F, Patil A, Nagathan P (2021b) Channel flow of MHD Bingham fluid due to peristalsis with multiple chemical reactions: an application to blood flow through narrow arteries. SN Appl Sci 3:186

    Google Scholar 

  • Vajravelu K, Sreenadh S, Lakshminarayana P, Sucharitha G, Rashidi MM (2016) Peristaltic flow of Phan-Thien-Tanner fluid in an asymmetric channel with porous medium. J Appl Fluid Mech 9:1615–1625

    Google Scholar 

  • Vajravelu K, Sreenadh S, Dhananjaya S, Lakshminarayana P (2016) Peristaltic flow and heat transfer of a conducing Phan-Thien-Tanner fluid in an asymmetric channel Application to chime movement in small intestine. Int J Appl Mech Eng 21:713–736

    Google Scholar 

  • Vajravelu K, Radhakrishnamacharya G, Radhakrishnamurty V (2007) Peristaltic flow and heat transfer in a vertical porous annulus with long wave approximation. Int J Nonlinear Mech 42(5):754–759

    MATH  Google Scholar 

  • Wang P, Yuan Y, Xu K, Zhong H, Yang Y, Jin S, Yang K, Qi X (2021) Biological applications of copper-containing materials. Bioact Mater 6:916–927

    Google Scholar 

  • Wu A, Abbas SZ, Asghar Z, Sun H, Waqas M, Khan WA (2020) A shear-rate-dependent flow generated via magnetically controlled metachronal motion of artificial cilia. Biomech Model Mechanobiol 19:1713–1724

    Google Scholar 

  • Xu H, Sun Q (2019) Generalized hybrid nanofluid model with the application of fully developed mixed convection flow in a vertical microchannel. Commun Theor Phys 71:903–911

    MathSciNet  Google Scholar 

  • Xu L, Wang YY, Huang J, Chen CY, Wang ZX, Xie H (2020) Silver Nanoparticles: Synthesis, medical applications and biosafety. Theranostics 10:8996–9031

    Google Scholar 

Download references

Acknowledgements

The authors are very grateful to anonymous reviewers for their fruitful comments and constructive suggestions to improve our manuscript.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Asgar Ali.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ali, A., Jana, R.N. & Das, S. Significance of entropy generation and heat source: the case of peristaltic blood flow through a ciliated tube conveying Cu-Ag nanoparticles using Phan-Thien-Tanner model. Biomech Model Mechanobiol 20, 2393–2412 (2021). https://doi.org/10.1007/s10237-021-01515-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10237-021-01515-8

Keywords

Navigation