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Homogenized stiffness matrices for mineralized collagen fibrils and lamellar bone using unit cell finite element models

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Abstract

Mineralized collagen fibrils have been usually analyzed like a two-phase composite material where crystals are considered as platelets that constitute the reinforcement phase. Different models have been used to describe the elastic behavior of the material. In this work, it is shown that when Halpin–Tsai equations are applied to estimate elastic constants from typical constituent properties, not all crystal dimensions yield a model that satisfy thermodynamic restrictions. We provide the ranges of platelet dimensions that lead to positive definite stiffness matrices. On the other hand, a finite element model of a mineralized collagen fibril unit cell under periodic boundary conditions is analyzed. By applying six canonical load cases, homogenized stiffness matrices are numerically calculated. Results show a monoclinic behavior of the mineralized collagen fibril. In addition, a 5-layer lamellar structure is also considered where crystals rotate in adjacent layers of a lamella. The stiffness matrix of each layer is calculated applying Lekhnitskii transformations, and a new finite element model under periodic boundary conditions is analyzed to calculate the homogenized 3D anisotropic stiffness matrix of a unit cell of lamellar bone. Results are compared with the rule-of-mixtures showing in general good agreement.

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Acknowledgments

The authors acknowledge the Ministerio de Economía y Competitividad the financial support given through the project DPI2010-20990 and the Generalitat Valenciana through the Programme Prometeo 2012/023. The authors thank Ms. Carla González Carrillo by her help in the development of some of the numerical models.

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  1. Depto. de Ingeniería Mecánica y de Materiales, Centro de Investigación de Tecnología de Vehículos—CITV, Universitat Politècnica de València, Camino de Vera, 46022 , Valencia, Spain

    Ana Vercher, Eugenio Giner, Camila Arango, José E. Tarancón & F. Javier Fuenmayor

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  1. Ana Vercher
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  2. Eugenio Giner
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  3. Camila Arango
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  4. José E. Tarancón
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  5. F. Javier Fuenmayor
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Correspondence to Ana Vercher.

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Vercher, A., Giner, E., Arango, C. et al. Homogenized stiffness matrices for mineralized collagen fibrils and lamellar bone using unit cell finite element models. Biomech Model Mechanobiol 13, 437–449 (2014). https://doi.org/10.1007/s10237-013-0507-y

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  • DOI: https://doi.org/10.1007/s10237-013-0507-y

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