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A case of aseptic abscesses syndrome treated with corticosteroids and TNF-alpha blockade

  • Case Report
  • Published:
Modern Rheumatology

Abstract

Aseptic abscesses syndrome (AA) is an emerging clinicopathological entity characterized by visceral sterile collections of mature neutrophils that do not respond to antibiotics but regress quickly when treated with corticosteroids. Although most previous case reports of AA have been restricted to Europe, we present here a Japanese woman with AA showing recurrence of splenic abscesses, ileocolitis, pyoderma gangrenosum, and arthritis. Although both steroid therapy and tumor necrosis factor (TNF)-alpha blockade were effective, relapses remained frequent.

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Authors and Affiliations

  1. Department of Internal Medicine, Nagaoka Red Cross Hospital, 2-297-1 Senshu, Nagaoka, Niigata, 940-2085, Japan

    Tomoyuki Ito, Naoko Sato, Hajime Yamazaki, Tadashi Koike & Takako Saeki

  2. Department of Pathology, Nagaoka Red Cross Hospital, 2-297-1 Senshu, Nagaoka, Niigata, 940-2085, Japan

    Iwao Emura

Authors
  1. Tomoyuki Ito
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  2. Naoko Sato
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  3. Hajime Yamazaki
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  4. Tadashi Koike
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  5. Iwao Emura
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  6. Takako Saeki
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Corresponding author

Correspondence to Tomoyuki Ito.

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Ito, T., Sato, N., Yamazaki, H. et al. A case of aseptic abscesses syndrome treated with corticosteroids and TNF-alpha blockade. Mod Rheumatol 23, 195–199 (2013). https://doi.org/10.1007/s10165-012-0640-y

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  • DOI: https://doi.org/10.1007/s10165-012-0640-y

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