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A case of chronic active Epstein–Barr virus infection mimicking adult-onset Still’s disease

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Modern Rheumatology

Abstract

An 83-year-old man was diagnosed with adult-onset Still’s disease (AOSD) based on clinical and laboratory findings. However, glucocorticoid had little effect. Epstein–Barr virus (EBV)-DNA was detected in peripheral blood, and autopsy findings confirmed a diagnosis of chronic active EBV infection (CAEBV). CAEBV mimics AOSD, and the presence of articular involvement and leukocytosis does not exclude the possibility of CAEBV. CAEBV should be included in the differential diagnosis of AOSD, and measurement of EBV-DNA is essential.

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Authors and Affiliations

  1. Department of Internal Medicine, Osaka City Sumiyoshi Hospital, 1-2-16 Higashikagaya, Suminoeku, Osaka, Osaka, 559-0012, Japan

    Katsunobu Yoshioka & Mieko Minami

  2. Department of Pathology, Osaka City General Hospital, Osaka, Japan

    Hiroko Fukushima, Naomi Ishii & Takeshi Inoue

  3. Department of Internal Medicine, Osaka City General Hospital, Osaka, Japan

    Akiko Kita, Yusuke Hanioka & Keiko Yamagami

Authors
  1. Katsunobu Yoshioka
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  2. Hiroko Fukushima
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  3. Naomi Ishii
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  4. Akiko Kita
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  5. Yusuke Hanioka
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  6. Mieko Minami
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  7. Takeshi Inoue
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  8. Keiko Yamagami
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Correspondence to Katsunobu Yoshioka.

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Yoshioka, K., Fukushima, H., Ishii, N. et al. A case of chronic active Epstein–Barr virus infection mimicking adult-onset Still’s disease. Mod Rheumatol 23, 162–166 (2013). https://doi.org/10.1007/s10165-012-0620-2

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  • DOI: https://doi.org/10.1007/s10165-012-0620-2

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