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Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome following spontaneous rupture of a gouty tophus

  • Case Report
  • Published:
Modern Rheumatology

Abstract

A 70-year-old man with a 30-year history of gout presented with a ruptured gouty tophus over the right lateral malleolus. After the debridement of the tophus, bilateral arthralgia and pitting edema were observed in his extremities. Treatments with antibiotics and nonsteroidal antiinflammatory drugs were ineffective. However, prednisolone therapy was highly effective, and the patient’s symptoms were rapidly ameliorated. Thus, we presume that rupture of a gouty tophus or its surgical treatment might contribute to the occurrence of RS3PE syndrome; however, in our case, the etiology of the syndrome remained unknown.

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Authors and Affiliations

  1. Division of Rheumatology, Jusendo General Hospital, 1-8-16 Ekimae, Koriyama, Fukushima, 963-8585, Japan

    Kota Sugisaki

  2. Division of Plastic and Reconstructive Surgery, Jusendo General Hospital, Koriyama, Fukushima, Japan

    Taro Hirose

Authors
  1. Kota Sugisaki
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  2. Taro Hirose
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Correspondence to Kota Sugisaki.

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Sugisaki, K., Hirose, T. Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome following spontaneous rupture of a gouty tophus. Mod Rheumatol 18, 630–633 (2008). https://doi.org/10.1007/s10165-008-0105-5

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  • DOI: https://doi.org/10.1007/s10165-008-0105-5

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