Abstract
We report a 16-year-old patient who developed concurrent poststreptococcal reactive arthritis and acute glomerulonephritis. A high titer of antistreptolysin O antibody confirmed the preceding streptococcal infection. The patient presented with symmetric persistent tenosynovitis of hands and feet. Renal biopsy showed typical findings of acute glomerulonephritis with crescent formation. Physicians who treat patients with arthritis of acute onset, especially after throat infection, should be aware of possible urinary abnormalities or renal dysfunction.
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References
Iglesias-Gamarra A, Mendez EA, Cuellar ML, Ponce de Leon JH, Jimenez C, Canãs C, et al. Poststreptococcal reactive arthritis in adults: long-term follow-up. Am J Med Sci. 2001;321:173–7.
Gutiérrez-Ureña S, Molina J, Molina JF, García CO, Cuéllar ML, Espinoza LR. Poststreptococcal reactive arthritis, clinical course, and outcome in 6 adult patients. J Rheumatol. 1995;22:1710–3.
Shulman ST, Ayoub EM. Poststreptococcal reactive arthritis. Curr Opin Rheumatol. 2002;14:562–5.
Moon RY, Greene MG, Rehe GT, Katona IM. Poststreptococcal reactive arthritis in children: a potential predecessor of rheumatic heart disease. J Rheumatol. 1995;22:529–32.
Ahmed S, Ayoub EM, Scornik JC, Wang C-Y, She J-X. Poststreptococcal reactive arthritis. Clinical characteristics and association with HLA-DR alleles. Arthritis Rheum. 1998;41:1096–102.
Richards J. Acute post-streptococcal glomerulonephritis. W V Med J. 1991;87:61–5.
Niewold TB, Ghosh AK. Post-streptococcal reactive arthritis and glomerulonephritis in an adult. Clin Rheumatol. 2003;22:350–2.
Mackie SL, Keat A. Poststreptococcal reactive arthritis: what is it and how do we know? Rheumatology. 2004;43:949–54.
Rodríguez-Iturbe B, Batsford S. Pathogenesis of poststreptococcal glomerulonephritis a century after Clemens von Pirquet. Kidney Int. 2007;71:1094–104.
Kaplan EL, Anthony BF, Chapman SS. Wannamaker LW: Epidemic acute glomerulonephritis associated with type 49 streptococcal pyoderma. I. Clinical and laboratory findings. Am J Med. 1970;48:9–27.
Silva FG. Acute postinfectious glomerulonephritis and glomerulonephritis complicating persistent bacterial infection. In: Jennette JC, Olson JL, Schwartz MM, Silva FG, editors. Heptinstall’s pathology of the kidney. Philadelphia: Lippincott-Raven; 1998. p. 389–453.
Pinto SW, Sesso R, Vasconcelos E, Watanabe YJ, Pansute AM. Follow-up of patients with epidemic poststreptococcal glomerulonephritis. Am J Kidney Dis. 2001;38:249–55.
Lien JW, Mathew TH, Meadows R. Acute post-streptococcal glomerulonephritis in adults: a long-term study. Q J Med. 1979;48:99–111.
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Tokura, T., Morita, Y., Yorimitsu, D. et al. Co-occurrence of poststreptococcal reactive arthritis and acute glomerulonephritis. Mod Rheumatol 18, 526–528 (2008). https://doi.org/10.1007/s10165-008-0095-3
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DOI: https://doi.org/10.1007/s10165-008-0095-3