Abstract
Takayasu's arteritis (TA) is a rare disease that can be difficult to diagnose in its early stage. A young woman with a fever and neck pain was thought to have TA, although computed tomographic angiography did not show any specific changes of the arteries. [18F]fluorodeoxyglucose positron emission tomography ([18F]FDG-PET) was performed to detect the source of the inflammation. Specific accumulation of [18F]FDG-6-phosphate in the thoracic aorta and its direct branches was observed, leading to a diagnosis of TA. [18F]FDG-PET is therefore considered to be useful for the diagnosis of early-stage TA.
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References
F Numano Y Kobayashi (1999) ArticleTitleTakayasu arteritis — beyond pulselessness Intern Med 38 226–32 Occurrence Handle10.2169/internalmedicine.38.226 Occurrence Handle1:STN:280:DyaK1M3mvVamsQ%3D%3D Occurrence Handle10337931
J Meller F Strutz U Siefker A Scheel CO Sahlmann K Lehmann et al. (2003) ArticleTitleEarly diagnosis and follow-up aortitis with [(18)F] FDG PET and MRI Eur J Nucl Med Mol Imaging 30 730–6 Occurrence Handle1:STN:280:DC%2BD3s3hvFSgtQ%3D%3D Occurrence Handle12677302 Occurrence Handle10.1007/s00259-003-1144-y
J Andrews A Al-Nahhas J Pennell S Hossain A Davies O Haskard et al. (2004) ArticleTitleNon-invasive imaging in the diagnosis and management of Takayasu's arteritis Ann Rheum Dis 63 995–1000 10.1136/ard.2003.015701 Occurrence Handle10.1136/ard.2003.015701 Occurrence Handle1:STN:280:DC%2BD2czksF2rsg%3D%3D Occurrence Handle15249328
N Matsunaga K Hayashi I Sakamoto Y Matsuoka Y Ogawa K Honjo et al. (1998) ArticleTitleTakayasu arteritis: MR manifestations and diagnosis of acute and chronic phase Magn Reson Imaging 8 406–14 Occurrence Handle10.1002/jmri.1880080221 Occurrence Handle1:STN:280:DyaK1c3itVGgtA%3D%3D
J Meller E Grappe W Becker R Vosshenrich (2003) ArticleTitleValue of F-18 FDG hybrid camera PET and MRI in early takayasu aortitis Eur Radiol 13 400–5 Occurrence Handle1:STN:280:DC%2BD3s%2Fos1yksg%3D%3D Occurrence Handle12599007
M Takayasu (1908) ArticleTitleA case with peculiar changes of the retinal central vessels (in Japanese) Acta Ophthalm Soc Japan 12 554–5
Shimizu K. Pulseless disease. J Neuropathol Clin Neurol 1951;1.37–1.47
WC Caccamise K Okuda (1954) ArticleTitleTakayasu's or pulseless disease: an unusual syndrome with ocular manifestations Am J Ophthalmol 37 784–6 Occurrence Handle1:STN:280:DyaG2c%2FnvVCmsQ%3D%3D Occurrence Handle13158475
AS Fauci (2001) The vasculitis syndromes E Braunwald AS Fauci DL Kasper SL Hauser DL Longo JL Jameson (Eds) Harrison's principles of internal medicine EditionNumber15th ed McGraw-Hill New York 1956–68
IW Uthman AR Bizri RA Hajj Ali FW Nasr IM Khalil (1999) ArticleTitleTakayasu's arteritis presenting as fever of unknown origin: report of two cases and literature review Semin Arthritis Rheum 28 280–5 10.1016/S0049-0172(99)80023-7 Occurrence Handle10.1016/S0049-0172(99)80023-7 Occurrence Handle1:STN:280:DyaK1M7ntFGisg%3D%3D Occurrence Handle10073502
K Sharma N Siveski-Iliskovic P Singal (1995) ArticleTitleTakayasu arteritis may be underdiagnosed in North America Can J Cardiol 11 311–6 Occurrence Handle1:STN:280:DyaK2M3ksF2juw%3D%3D Occurrence Handle7728643
MB Gotway PA Araoz TA Macedo AW Stanson CB Higgins EJ Ring et al. (2005) ArticleTitleImaging findings in Takayasu's arteritis AJR 184 1945–50 Occurrence Handle15908559
E Angeli A Vanzulli M Venturini B Zoccai A Del Maschio (2001) ArticleTitleThe role of radiologyi the diagnosis and management of Takayasu's arteritis J Nephrol 14 514–24 Occurrence Handle1:STN:280:DC%2BD38%2FlvVGhsg%3D%3D Occurrence Handle11783608
A Muthumala D Appleton J Gaston (2002) ArticleTitleDiagnosis of Takayasu's arteritis by unexpected findings on abdominal CT scan Ann Rheum Dis 61 1035–6 10.1136/ard.61.11.1035 Occurrence Handle10.1136/ard.61.11.1035 Occurrence Handle1:STN:280:DC%2BD38nitFOktg%3D%3D Occurrence Handle12379535
H Choe K Kim M Koh S Do R Lee (1999) ArticleTitleTakayasu arteritis: diagnosis with MR imaging and MR angiography in acute and chronic active stages J Magn Reson Imaging 10 751–7 10.1002/(SICI)1522-2586(199911)10:5<751::AID-JMRI20>3.0.CO;2-Y Occurrence Handle10.1002/(SICI)1522-2586(199911)10:5<751::AID-JMRI20>3.0.CO;2-Y Occurrence Handle1:STN:280:DC%2BD3c%2FhvVSltQ%3D%3D Occurrence Handle10548785
J Lorenzen R Buchert H Bohuslavski (2001) ArticleTitleValue of FDG PET in patients with fever of unknown origin Nucl Med Commun 22 779–83 10.1097/00006231-200107000-00009 Occurrence Handle10.1097/00006231-200107000-00009 Occurrence Handle1:STN:280:DC%2BD38%2FitFaluw%3D%3D Occurrence Handle11453051
D Blockmans D Knockaert A Maes J De Caestecker S Stroobants H Bobbaers et al. (2001) ArticleTitleClinical value of [(18)F] fluoro-deoxyglucose positron emission tomography for patients with fever of unknown origin Clin Infect Dis 32 191–6 10.1086/318480 Occurrence Handle10.1086/318480 Occurrence Handle1:STN:280:DC%2BD3M3htlGiuw%3D%3D Occurrence Handle11170907
N Matsunaga K Hayashi I Sakamoto Y Matsuoka Y Ogawa K Honjo et al. (1998) ArticleTitleTakayasu arteritis: MR manifestations and diagnosis of acute and chronic phase Magn Reson Imaging 8 406–14 Occurrence Handle10.1002/jmri.1880080221 Occurrence Handle1:STN:280:DyaK1c3itVGgtA%3D%3D
A Kjaer AM Lebech A Eigtved L Hojgaard (2004) ArticleTitleFever of unknown origin: prospective comparison of diagnostic value of 18F-FDG PET and 111In-granulocyte scintigraphy Eur J Nucl Med Mol Imaging 31 622–6 10.1007/s00259-003-1425-5 Occurrence Handle10.1007/s00259-003-1425-5 Occurrence Handle14730403
J Meller G Altenvoerde U Munzel A Jauho M Behe S Gratz et al. (2000) ArticleTitleFever of unknown origin: prospective comparison of 18 FDG-imaging with a double-head coincidence camera and gallium-67 citrate SPECT Eur J Nucl Med 27 1617–25 10.1007/s002590000341 Occurrence Handle10.1007/s002590000341 Occurrence Handle1:CAS:528:DC%2BD3cXosVWlsro%3D Occurrence Handle11105817
I Derdelinckx A Maes J Bogaert L Mortelmans D Blockmans (2000) ArticleTitlePositron emission tomography scan in the diagnosis and follow-up of aortitis of the thoracic aorta Acta Cardiol 55 193–5 10.2143/AC.55.3.2005739 Occurrence Handle10.2143/AC.55.3.2005739 Occurrence Handle1:STN:280:DC%2BD3M%2FivVOksw%3D%3D Occurrence Handle10902045
M Weiner P Vaith A Walker I Brink (2004) ArticleTitleDetection of alterations in brain glucose metabolism by positron emission tomography in Takayasu's arteritis Eur J Nucl Med Mol Imaging 31 300–2 10.1007/s00259-003-1373-0 Occurrence Handle10.1007/s00259-003-1373-0 Occurrence Handle15129714
M Webb A Chambers A Al-Nahhas JC Mason L Maudlin L Rahman et al. (2004) ArticleTitleThe role of 18F-FDG PET in characterising disease activity in Takayasu arteritis Eur J Nucl Med Mol Imaging 31 627–34 10.1007/s00259-003-1429-1 Occurrence Handle10.1007/s00259-003-1429-1 Occurrence Handle14730404
Y Kobayashi K Ishii K Oda T Nariai Y Tanaka F Numano et al. (2005) ArticleTitleAortic wall inflammation due to Takayasu arteritis imaged with 18F-FDG PET coregistered with enhanced CT J Nucl Med 46 917–22 Occurrence Handle15937300
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Umekita, K., Takajo, I., Miyauchi, S. et al. [18F]fluorodeoxyglucose positron emission tomography is a useful tool to diagnose the early stage of Takayasu's arteritis and to evaluate the activity of the disease. Mod Rheumatol 16, 243–247 (2006). https://doi.org/10.1007/s10165-006-0485-3
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DOI: https://doi.org/10.1007/s10165-006-0485-3