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Drug eruption due to bosentan in a patient with systemic sclerosis

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Modern Rheumatology

Abstract

We present the case of a 60-year-old female patient with systemic sclerosis complicated by pulmonary hypertension. Ten days after the initiation of treatment with bosentan, high fever and skin eruptions were noted. In the previous reports, the frequency of drug-induced skin eruptions has not been well documented. Since the use of bosentan is expected to increase, we should be aware of the previously unknown adverse effects as well as skin eruptions.

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Authors and Affiliations

  1. Department of Dermatology, Gunma University Graduate School of Medicine, 3-39-22 Showamachi, Maebashi, 371-8511, Japan

    Yayoi Nagai, Masayoshi Yamanaka & Osamu Ishikawa

  2. Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan

    Shigeru Nishimura, Akihiko Nakano & Akira Hasegawa

Authors
  1. Yayoi Nagai
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  2. Masayoshi Yamanaka
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  3. Shigeru Nishimura
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  4. Akihiko Nakano
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  5. Akira Hasegawa
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  6. Osamu Ishikawa
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Corresponding author

Correspondence to Yayoi Nagai.

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Nagai, Y., Yamanaka, M., Nishimura, S. et al. Drug eruption due to bosentan in a patient with systemic sclerosis. Mod Rheumatol 16, 188–190 (2006). https://doi.org/10.1007/s10165-006-0477-3

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  • DOI: https://doi.org/10.1007/s10165-006-0477-3

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