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A case of severe acute pancreatitis, in overlap syndrome of systemic sclerosis and systemic lupus erythematosus, successfully treated with plasmapheresis

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Modern Rheumatology

Abstract

Here, we describe a case of severe pancreatitis in overlap syndrome of systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) in an adult female patient. Treatment with plasmapheresis and high-dose prednisone successfully saved her life and led to remission of the pancreatitis. This is the first case report of severe acute pancreatitis in the setting of overlap syndrome of SLE and SSc. The advantages and disadvantages of the use of corticosteroids are discussed.

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References

  1. V Pascual-Ramos A Duarte-Rojo AR Villa B Hernandez-Cruz D Alarcon-Segovia J Alcocer-Varela et al. (2004) ArticleTitleSystemic lupus erythematosus as a cause and prognostic factor of acute pancreatitis J Rheumatol 31 707–12 Occurrence Handle15088295

    PubMed  Google Scholar 

  2. M Borum W Steinberg M Steer S Freedman P White (1993) ArticleTitleChronic pancreatitis: a complication of systemic lupus erythematosus Gastroenterology 104 613–5 Occurrence Handle1:STN:280:DyaK3s7ks1ejsw%3D%3D Occurrence Handle8425705

    CAS  PubMed  Google Scholar 

  3. E Ossi U Fiocco M Belloni G Ongaro L Rubaltelli A Ruffatti et al. (1983) ArticleTitleTherapy of acute pancreatitis in systemic lupus erythematosus with plasmapheresis and corticosteroids Clin Exp Rheumatol 1 345–7 Occurrence Handle1:STN:280:DyaL2M7nslyjug%3D%3D Occurrence Handle6681152

    CAS  PubMed  Google Scholar 

  4. S Zanen A Brand A Cats (1983) ArticleTitleAcute pancreatitis in systemic lupus erythematosus (SLE). Successful treatment with plasmapheresis after failure of prednisone Clin Exp Rheumatol 1 341–4 Occurrence Handle1:STN:280:DyaL2M7nslyjtQ%3D%3D Occurrence Handle6681151

    CAS  PubMed  Google Scholar 

  5. VE Pollak WJ Grove RM Kark RC Muehrcke CL Pirani IE Steck (1958) ArticleTitleSystemic lupus erythematosus simulating acute surgical condition of the abdomen N Engl J Med 258 IssueID7 258–66 Occurrence Handle10.1056/NEJM195808072590602

    Article  Google Scholar 

  6. CR Wang HC Hsieh GL Lee CY Chuang CY Chen (1992) ArticleTitlePancreatitis related to antiphospholipid antibody syndrome in a patient with systemic lupus erythematosus J Rheumatol 19 1123–5 Occurrence Handle1:STN:280:DyaK38zotFOiuw%3D%3D Occurrence Handle1512770

    CAS  PubMed  Google Scholar 

  7. T Hashimoto T Yamada T Yokoi H Sano H Ando T Nakazawa et al. (2000) ArticleTitleApoptosis of acinar cells is involved in chronic pancreatitis in Wbn/Kob rats: role of glucocorticoids Pancreas 21 296–304 10.1097/00006676-200010000-00012 Occurrence Handle10.1097/00006676-200010000-00012 Occurrence Handle1:STN:280:DC%2BD3cvovVGitw%3D%3D Occurrence Handle11039475

    Article  CAS  PubMed  Google Scholar 

  8. S Saab MP Corr MH Weisman (1998) ArticleTitleCorticosteroids and systemic lupus erythematosus pancreatitis: a case series J Rheumatol 25 801–6 Occurrence Handle1:STN:280:DyaK1c3hslaksQ%3D%3D Occurrence Handle9558190

    CAS  PubMed  Google Scholar 

  9. M Funauchi S Ikoma H Enomoto A Horiuchi (1998) ArticleTitleDecreased Th1-like and increased Th2-like cells in systemic lupus erythematosus Scand J Rheumatol 27 19–24

    Google Scholar 

  10. H Okamoto K Koizumi H Yamanaka T Saito N Kamatani (2003) ArticleTitleA role for TARC/CCL17, a CC chemokine, in systemic lupus erythematosus J Rheumatol 30 2369–73 Occurrence Handle1:CAS:528:DC%2BD2cXhvFagsL8%3D Occurrence Handle14677179

    CAS  PubMed  Google Scholar 

  11. M Akahoshi H Nakashima Y Tanaka T Kohsaka S Nagano E Ohgami et al. (1999) ArticleTitleTh1/Th2 balance of peripheral T helper cells in systemic lupus erythematosus Arthritis Rheum 42 1644–8 10.1002/1529-0131(199908)42:8<1644::AID-ANR12>3.0.CO;2-L Occurrence Handle10.1002/1529-0131(199908)42:8<1644::AID-ANR12>3.0.CO;2-L Occurrence Handle1:CAS:528:DyaK1MXlsFyntro%3D Occurrence Handle10446863

    Article  CAS  PubMed  Google Scholar 

  12. H Okamoto Y Katsumata K Nishimura N Kamatani (2004) ArticleTitleInterferon-inducible protein 10/CXCL10 is increased in the cerebrospinal fluid of patients with central nervous system lupus Arthritis Rheum 50 3731–2 10.1002/art.20598 Occurrence Handle10.1002/art.20598 Occurrence Handle1:CAS:528:DC%2BD2cXhtVOqtrbM Occurrence Handle15529358

    Article  CAS  PubMed  Google Scholar 

  13. S Uehara K Gothoh H Handa H Tomita Y Tomita (2003) ArticleTitleImmune function in patients with acute pancreatitis J Gastroenterol Hepatol 18 363–70 10.1046/j.1440-1746.2003.02979.x Occurrence Handle10.1046/j.1440-1746.2003.02979.x Occurrence Handle1:CAS:528:DC%2BD3sXkt1GmsbY%3D Occurrence Handle12653883

    Article  CAS  PubMed  Google Scholar 

  14. K Uchida K Okazaki T Nishi S Uose H Nakase M Ohana et al. (2002) ArticleTitleExperimental immune-mediated pancreatitis in neonatally thymectomized mice immunized with carbonic anhydrase II and lactoferrin Lab Invest 82 411–24 Occurrence Handle1:CAS:528:DC%2BD38XjvVKhurk%3D Occurrence Handle11950899

    CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Institute of Rheumatology, Tokyo Women’s Medical University, 10-22 Kawada-cho, Shinjuku-ku, Tokyo, 162-0054, Japan

    Yukie Suzuki, Hiroshi Okamoto, Kyoko Koizumi, Mutsuto Tateishi, Masako Hara & Naoyuki Kamatani

  2. Department of Rheumatology, Tokyo Metropolitan Ohtsuka Hospital, Tokyo, Japan

    Mutsuto Tateishi

Authors
  1. Yukie Suzuki
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  2. Hiroshi Okamoto
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  3. Kyoko Koizumi
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  4. Mutsuto Tateishi
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  5. Masako Hara
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  6. Naoyuki Kamatani
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Corresponding author

Correspondence to Hiroshi Okamoto.

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Cite this article

Suzuki, Y., Okamoto, H., Koizumi, K. et al. A case of severe acute pancreatitis, in overlap syndrome of systemic sclerosis and systemic lupus erythematosus, successfully treated with plasmapheresis. Mod Rheumatol 16, 172–175 (2006). https://doi.org/10.1007/s10165-006-0476-4

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  • DOI: https://doi.org/10.1007/s10165-006-0476-4

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