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Systemic sclerosis and pseudomesotheliomatous adenocarcinoma of the lung

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Modern Rheumatology

Abstract

A 55-year-old man, diagnosed with systemic sclerosis (SSc) for 20 years, was admitted to our hospital for exertional dyspnea and pleural effusion. Computed tomography scan and cytological findings of the pleural fluid suggested malignant mesothelioma. In the postmortem examination, the tumor was pathologically diagnosed as pseudomesotheliomatous adenocarcinoma (PMA) of the lung, classified into pleomorphic carcinoma with adenocarcinoma component according to the new World Health Organization guidelines. This is the first case report of SSc with PMA.

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Authors and Affiliations

  1. Department of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan

    Ryusuke Yoshimi, Mitsuhiro Takeno, Yohei Kirino, Yukiko Takeda, Akiko Sekiguchi, Hiroshi Kobayashi, Atsushi Ihata, Kyosuke Motoji, Atsuhisa Ueda, Takayoshi Soga & Yoshiaki Ishigatsubo

  2. Division of Anatomic and Surgical Pathology, Hospital of Yokohama City University, Yokohama, Japan

    Shoji Yamanaka

  3. Department of Biochemistry, Yokohama City University Graduate School of Medicine, Yokohama, Japan

    Masaaki Shiina

  4. Chronic Intractable Center, Yokohama City University Medical Center, Yokohama, Japan

    Shigeru Ohno

Authors
  1. Ryusuke Yoshimi
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  2. Mitsuhiro Takeno
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  3. Shoji Yamanaka
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  4. Masaaki Shiina
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  5. Yohei Kirino
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  14. Yoshiaki Ishigatsubo
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Corresponding author

Correspondence to Ryusuke Yoshimi.

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Yoshimi, R., Takeno, M., Yamanaka, S. et al. Systemic sclerosis and pseudomesotheliomatous adenocarcinoma of the lung. Mod Rheumatol 16, 165–168 (2006). https://doi.org/10.1007/s10165-006-0472-8

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  • DOI: https://doi.org/10.1007/s10165-006-0472-8

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