Modern Rheumatology

, Volume 15, Issue 3, pp 198–200 | Cite as

Progressive facial hemiatrophy complicated by sclerodactyly, Raynaud’s phenomenon, anti-ribonucleoprotein antibody, and trigeminal nerve disturbance

  • Ken HamasakiEmail author
  • Kanae Kubo
  • Hiroko Kanda


A Japanese woman was diagnosed as having progressive facial hemiatrophy when she was 26 years old. After 30 years, Raynaud’s phenomenon and sclerodactyly suddenly appeared; at the same time, positive rheumatoid factor and anti-ribonucleoprotein (anti-RNP) antibody were noted on serological examinations. When she was 60 years old, trigeminal nerve disturbance also appeared. The associations between progressive facial hemiatrophy, systemic scleroderma, and trigeminal nerve disturbance are interesting and should be discussed.

Key words

Anti-ribonucleoprotein (anti-RNP) antibody Progressive facial hemiatrophy Raynaud’s phenomenon Sclerodactyly Trigeminal nerve disturbance 


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Copyright information

© Japan College of Rheumatology and Springer-Verlag Tokyo 2005

Authors and Affiliations

  1. 1.Department of RheumatologyTokyo Metropolitan Geriatric HospitalTokyoJapan
  2. 2.Department of Allergy and Rheumatology, Faculty of MedicineUniversity of TokyoTokyoJapan

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