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MPO-ANCA-positive Wegener’s granulomatosis presenting with hypertrophic cranial pachymeningitis: case report and review of the literature

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Modern Rheumatology

Abstract

We describe a case of hypertrophic cranial pachymeningitis (HCP) associated with Wegener’s granulomatosis (WG) in a 60-year-old man presenting with chronic headache and multiple cranial nerve neuropathies. A test for antibodies to the neutrophil cytoplasmic protein myeloperoxidase (MPO-ANCA) was positive in this case. We review the literature on perinuclear (p)-ANCA-related HCP, including our case. This case indicates the link between MPO-ANCA-positive WG and HCP.

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Correspondence to Hitoshi Nakashima.

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Akahoshi, M., Yoshimoto, G., Nakashima, H. et al. MPO-ANCA-positive Wegener’s granulomatosis presenting with hypertrophic cranial pachymeningitis: case report and review of the literature. Mod Rheumatol 14, 179–183 (2004). https://doi.org/10.1007/s10165-004-0288-3

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  • DOI: https://doi.org/10.1007/s10165-004-0288-3

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