An inpatient educational program for chronic kidney disease

  • Shinji Machida
  • Yugo Shibagaki
  • Tsutomu SakuradaEmail author
Original article



Chronic kidney disease (CKD) is a significant health problem in Japan, and prevention programs to slow disease progression are necessary. In this study, we evaluated the effectiveness of a 1-week inpatient education program, delivered during the predialysis stage of CKD, in slowing the deterioration in renal function over the subsequent 2 years, and identified factors influencing the program’s effectiveness.


We retrospectively evaluated the estimated glomerular filtration rate (eGFR) of 105 consecutive patients who completed the program, at the following time points: 6 months prior to program initiation, at program initiation and, at 6, 12, 18, and 24 months after the program. To identify factors predictive of program effectiveness, we classified patients into a Responder and Non-responder group.


In comparison with the rate of deterioration in renal function (mL/min/1.73 m2/year) before admission, the rate slowed at 6, 12, 18 and 24 months after discharge (all p < 0.01). A urinary protein (UP) level <0.5 g/gCr and CKD stages 4–5 were predictive of a slowing of CKD progression after the education program.


Although the effectiveness of our program declined over time, it did produce an overall slowing in the rate of renal function deterioration over the 2-year period of observation after discharge. This slowing of CKD progression was more pronounced in patients with low UP levels, indicating that education programs should be considered while these levels are still low. Furthermore, the program still offers benefits to patients with CKD stages 4–5.


Chronic kidney disease Education program Predialysis Renal function 



We gratefully acknowledge Koji Hiraki, Michi Shibata, and Mie Tagaya for collecting the data of this study.

Compliance with ethical standards

Conflict of interest

The authors have no conflicts of interest regarding this study.

Ethics standards

Our study protocol was approved by the Ethics Committee of St. Marianna Medical University Hospital (approval no. 3923), with the need for informed consent waived due to the retrospective nature of the study.


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Copyright information

© Japanese Society of Nephrology 2018

Authors and Affiliations

  • Shinji Machida
    • 1
  • Yugo Shibagaki
    • 1
  • Tsutomu Sakurada
    • 1
    Email author
  1. 1.Department of Nephrology and HypertensionSt. Marianna University School of MedicineKawasakiJapan

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