Night-time blood pressure and pulse wave velocity in dialysis patients

  • Xiurong Li
  • Qingbo Jiang
  • Wenhui Wu
  • Xianlin Xu
  • Liying Miao
  • Lina Jin
  • Lina Xue
  • Tian Huang
  • Jia Di
  • Jinfeng Liu
  • Xiaozhou He
Original article

Abstract

Background

Ambulatory blood pressure (ABP) monitoring and carotid-femoral pulse wave velocity (cfPWV) provide important cardiovascular risk information for dialysis patients. This study aims to evaluate the risk factors of cfPWV and the associations between ambulatory blood pressure, especially night-time blood pressure and cfPWV.

Methods

We conducted a cross-sectional study in patients on maintenance hemodialysis. ABP and cfPWV were measured on a midweek interdialytic day. Associations were determined using Pearson’s correlation analysis and multiple stepwise regression model.

Results

Systolic BPs and pulse pressures, but not diastolic BPs, were significantly and positively associated with cfPWV. In a stepwise regression model, age, diabetes mellitus and all-period systolic BP were independently associated with cfPWV. When day-time and night-time BPs were included in the analysis, respectively, only night-time systolic BP and age remained as independently associated with cfPWV.

Conclusion

Ambulatory BPs are potent associates of cfPWV and night-time systolic BP, rather than day-time BPs, is an independently predictor of cfPWV. Our results support the view that controlling of nocturnal hypertension provides a unique cardiovascular protection effect.

Keywords

Ambulatory blood pressure Blood pressure Hypertension PWV Dialysis 

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Copyright information

© Japanese Society of Nephrology 2017

Authors and Affiliations

  • Xiurong Li
    • 1
  • Qingbo Jiang
    • 2
  • Wenhui Wu
    • 1
  • Xianlin Xu
    • 3
  • Liying Miao
    • 1
  • Lina Jin
    • 1
  • Lina Xue
    • 1
  • Tian Huang
    • 1
  • Jia Di
    • 1
  • Jinfeng Liu
    • 1
    • 2
    • 3
  • Xiaozhou He
    • 1
    • 3
  1. 1.Department of HemodialysisThe Third Affiliated Hospital of Soochow UniversityChangzhouChina
  2. 2.Department of LaboratoryThe Third Affiliated Hospital of Soochow UniversityChangzhouChina
  3. 3.Department of UrologyThe Third Affiliated Hospital of Soochow UniversityChangzhouChina

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