Home-based versus center-based aerobic exercise on cardiopulmonary performance, physical function, quality of life and quality of sleep of overweight patients with chronic kidney disease
The association between chronic kidney disease (CKD) and obesity can decrease the patients’ cardiopulmonary capacity, physical functioning and quality of life. The search for effective and practical alternative methods of exercise to engage patients in training programs is of great importance. Therefore, we aimed to compare the effects of home-based versus center-based aerobic exercise on the cardiopulmonary and functional capacities, quality of life and quality of sleep of overweight non-dialysis-dependent patients with CKD (NDD-CKD).
Forty sedentary overweight patients CKD stages 3 and 4 were randomly assigned to an exercise group [home-based group (n = 12) or center-based exercise group (n = 13)] or to a control group (n = 15) that did not perform any exercise. Cardiopulmonary exercise test, functional capacity tests, quality of life, quality of sleep and clinical parameters were assessed at baseline, 12 and 24 weeks.
The VO2peak and all cardiopulmonary parameters evaluated were similarly improved (p < 0.05) after 12 and 24 weeks in both exercise groups. The functional capacity tests improved during the follow-up in the home-based group (p < 0.05) and reached values similar to those obtained in the center-based group. The benefits achieved in both exercise groups were also reflected in improvement of quality of life and sleep (p < 0.05). No differences were observed between the exercise groups, and no changes in any of the parameters investigated were found in the control group.
Home-based aerobic training was as effective as center-based training in improving the physical and functional capabilities, quality of life and sleep in overweight NDD-CKD patients.
KeywordsAerobic exercise Chronic kidney disease Home-based exercise Obesity Physical function Quality of sleep
This study was supported by São Paulo Research Foundation (FAPESP) (2009/14786-0), Coordination for the Improvement of Higher Education Personnel (CAPES), Oswaldo Ramos Foundation, Psychobiology and Exercise Study Centre (CEPE) and the Research Incentive Fund Association (AFIP).
Compliance with ethical standards
Conflict of interest
The authors have no conflicts of interest to disclose.
All procedures performed were in accordance with the ethical standards of the Human Investigation Review Committee of Federal University of São Paulo that approved the study.
Informed consent was obtained from all individual participants included in the study.
- 11.Zhang JG, Ohta T, Ishikawa-Takata K, Tabata I, Miyashita M. Effects of daily activity recorded by pedometer on peak oxygen consumption (VO2peak), ventilatory threshold and leg extension power in 30- to 69-year-old Japanese without exercise habit. Eur J Appl Physiol. 2003;90(1–2):109–13. doi: 10.1007/s00421-003-0860-0.CrossRefPubMedGoogle Scholar
- 13.American College of Sports Medicine Position Stand. The recommended quantity and quality of exercise for developing and maintaining cardiorespiratory and muscular fitness, and flexibility in healthy adults. Med Sci Sports Exerc. 1998;30(6):975–91.Google Scholar
- 15.Rikli RE, Jones C. Development and validation of functional fitness test for community-residing older adults. J Aging Phys Act. 1999;6:127–59.Google Scholar
- 21.Mustata S, Groeneveld S, Davidson W, Ford G, Kiland K, Manns B. Effects of exercise training on physical impairment, arterial stiffness and health-related quality of life in patients with chronic kidney disease: a pilot study. Int Urol Nephrol. 2011;43(4):1133–41. doi: 10.1007/s11255-010-9823-7.CrossRefPubMedGoogle Scholar
- 25.Avesani CM, Trolonge S, Fau-Deleaval P, Deleaval P, Fau-Baria F, Baria F, Fau-Mafra D, Mafra D, Fau-Faxen-Irving G, Faxen-Irving G, Fau-Chauveau P, et al. Physical activity and energy expenditure in haemodialysis patients: an international survey. Nephrol Dial Transplant. 2012;27:1460–2385. doi: 10.1093/ndt/gfr692.CrossRefGoogle Scholar
- 35.Nonoyama ML, Brooks D, Ponikvar A, Jassal SV, Kontos P, Devins GM, Heck C, Laprade J, Naglie G. Exercise program to enhance physical performance and quality of life of older hemodialysis patients: a feasibility study. Int Urol Nephrol. 2010;42(4):1125–30. doi: 10.1007/s11255-010-9718-7.CrossRefPubMedPubMedCentralGoogle Scholar
- 41.Sakkas GK, Gourgoulianis KI, Karatzaferi C, Liakopoulos V, Maridaki MD, Pastaka C, et al. Haemodialysis patients with sleep apnoea syndrome experience increased central adiposity and altered muscular composition and functionality. Nephrol Dial Transpl. 2008;23(1):336–44. doi: 10.1093/ndt/gfm559.CrossRefGoogle Scholar
- 54.Dalal HM, Evans PH, Campbell JL, Taylor RS, Watt A, Read KL, et al. Home-based versus hospital-based rehabilitation after myocardial infarction: a randomized trial with preference arms—Cornwall Heart Attack Rehabilitation Management Study (CHARMS). Int J Cardiol. 2007;119(2):202–11. doi: 10.1016/j.ijcard.2006.11.018.CrossRefPubMedGoogle Scholar