Clinical and Experimental Nephrology

, Volume 22, Issue 1, pp 87–98 | Cite as

Home-based versus center-based aerobic exercise on cardiopulmonary performance, physical function, quality of life and quality of sleep of overweight patients with chronic kidney disease

  • Danilo Takashi Aoike
  • Flavia Baria
  • Maria Ayako Kamimura
  • Adriano Ammirati
  • Lilian CuppariEmail author
Original article



The association between chronic kidney disease (CKD) and obesity can decrease the patients’ cardiopulmonary capacity, physical functioning and quality of life. The search for effective and practical alternative methods of exercise to engage patients in training programs is of great importance. Therefore, we aimed to compare the effects of home-based versus center-based aerobic exercise on the cardiopulmonary and functional capacities, quality of life and quality of sleep of overweight non-dialysis-dependent patients with CKD (NDD-CKD).


Forty sedentary overweight patients CKD stages 3 and 4 were randomly assigned to an exercise group [home-based group (n = 12) or center-based exercise group (n = 13)] or to a control group (n = 15) that did not perform any exercise. Cardiopulmonary exercise test, functional capacity tests, quality of life, quality of sleep and clinical parameters were assessed at baseline, 12 and 24 weeks.


The VO2peak and all cardiopulmonary parameters evaluated were similarly improved (p < 0.05) after 12 and 24 weeks in both exercise groups. The functional capacity tests improved during the follow-up in the home-based group (p < 0.05) and reached values similar to those obtained in the center-based group. The benefits achieved in both exercise groups were also reflected in improvement of quality of life and sleep (p < 0.05). No differences were observed between the exercise groups, and no changes in any of the parameters investigated were found in the control group.


Home-based aerobic training was as effective as center-based training in improving the physical and functional capabilities, quality of life and sleep in overweight NDD-CKD patients.


Aerobic exercise Chronic kidney disease Home-based exercise Obesity Physical function Quality of sleep 



This study was supported by São Paulo Research Foundation (FAPESP) (2009/14786-0), Coordination for the Improvement of Higher Education Personnel (CAPES), Oswaldo Ramos Foundation, Psychobiology and Exercise Study Centre (CEPE) and the Research Incentive Fund Association (AFIP).

Compliance with ethical standards

Conflict of interest

The authors have no conflicts of interest to disclose.

Ethical statement

All procedures performed were in accordance with the ethical standards of the Human Investigation Review Committee of Federal University of São Paulo that approved the study.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Japanese Society of Nephrology 2017

Authors and Affiliations

  • Danilo Takashi Aoike
    • 1
  • Flavia Baria
    • 2
  • Maria Ayako Kamimura
    • 1
    • 2
  • Adriano Ammirati
    • 1
  • Lilian Cuppari
    • 1
    • 2
    Email author
  1. 1.Division of NephrologyFederal University of São PauloSão PauloBrazil
  2. 2.Nutrition ProgramFederal University of São PauloSão PauloBrazil

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