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Table 4 Incidence rates of the primary and secondary endpoints

From: Risk factors for CKD progression in Japanese patients: findings from the Chronic Kidney Disease Japan Cohort (CKD-JAC) study

CKD stages Primary endpointa Secondary endpoints
Rate of decline in eGFR from baseline Time to a 50 % decline in eGFR from baseline Time to the initiation of RRT Time to doubling of serum Cre concentration
G3a 18.3 NC 17.4 4.5 16.4
G3b 28.1 NC 27.0 13.1 22.8
G4 96.4 NC 82.0 63.1 68.9
G5 439.4 NC 101.1 265.7 68.2
  1. Values are expressed as number of renal events (rate per 1000 person-years of follow-up)
  2. aA composite of time to a 50 % decline in eGFR from baseline or time to the initiation of RRT
  3. Stage G3a, eGFR: 45–59 mL/min/1.73 m2; stage G3b, eGFR: 30–44 mL/min/1.73 m2; stage G4, eGFR: 15–29 mL/min/1.73 m2; stage G5, eGFR: <15 mL/min/1.73 m2
  4. CKD chronic kidney disease, eGFR estimated glomerular filtration rate, RRT renal replacement therapy, Cre creatinine, NC not calculable