Skip to main content
Log in

Recapitulation of kidney development paradigms by BMP-7 reverses chronic renal injury

  • REVIEW ARTICLE
  • Published:
Clinical and Experimental Nephrology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. G Remuzzi T Bertani (1998) ArticleTitlePathophysiology of progressive nephropathies N Engl J Med 390 1448–56 Occurrence Handle10.1056/NEJM199811123392007

    Article  Google Scholar 

  2. JV Bonventre (2003) ArticleTitleDedifferentiation and proliferation of surviving epithelial cells in acute renal failure J Am Soc Nephrol 14 S55–S61 Occurrence Handle10.1097/01.ASN.0000067652.51441.21 Occurrence Handle12761240

    Article  PubMed  Google Scholar 

  3. M Zeisberg J Hanai H Sugimoto T Mammoto D Charytan F Strutz et al. (2003) ArticleTitleBMP-7 counteracts TGF-β1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury Nat Med 9 964–8 Occurrence Handle10.1038/nm888 Occurrence Handle1:CAS:528:DC%2BD3sXkvFOjs7Y%3D Occurrence Handle12808448

    Article  CAS  PubMed  Google Scholar 

  4. LD Dworkin R Gong E Tolbert J Centraccio N Yano AR Zanabi et al. (2004) ArticleTitleHepatocyte growth factor ameliorates progression of interstitial fibrosis in rats with established renal injury Kidney Int 65 409–19 Occurrence Handle10.1111/j.1523-1755.2004.00417.x Occurrence Handle1:CAS:528:DC%2BD2cXhsVSnsLw%3D Occurrence Handle14717911

    Article  CAS  PubMed  Google Scholar 

  5. H Okada Y Watanabe T Kikuta T Kobayashi Y Kanno T Sugaya et al. (2004) ArticleTitleBradykinin decreases plasminogen activator inhibitor-1 expression and facilitates matrix degradation in the renal tubulointerstitium under angiotensin-converting enzyme blockade J Am Soc Nephrol 15 2402–13 Occurrence Handle10.1097/01.ASN.0000136132.20189.95

    Article  Google Scholar 

  6. KC Flanders (2004) ArticleTitleSmad3 as a mediator of the fibrotic response Int J Exp Pathol 85 47–64 Occurrence Handle10.1111/j.0959-9673.2004.00377.x Occurrence Handle1:CAS:528:DC%2BD2cXlt1Wqsrg%3D Occurrence Handle15154911

    Article  CAS  PubMed  Google Scholar 

  7. A Leask DJ Abraham (2004) ArticleTitleGF-β signaling and the fibrotic response FASEB J 18 816–27 Occurrence Handle10.1096/fj.03-1273rev Occurrence Handle1:CAS:528:DC%2BD2cXjvVOnt70%3D Occurrence Handle15117886

    Article  CAS  PubMed  Google Scholar 

  8. R Kalluri M Zeisberg (2003) ArticleTitleExploring the connection between chronic renal fibrosis and bone morphogenic protein-7 Histol Histopathol 18 217–24 Occurrence Handle1:CAS:528:DC%2BD3sXht1Wrsrc%3D Occurrence Handle12507301

    CAS  PubMed  Google Scholar 

  9. RP Ray KA Wharton (2001) ArticleTitleTwisted perspective: new insights into extracellular modulation of BMP signaling during development Cell 104 801–4 Occurrence Handle10.1016/S0092-8674(01)00275-6 Occurrence Handle1:CAS:528:DC%2BD3MXisVyisro%3D Occurrence Handle11290316

    Article  CAS  PubMed  Google Scholar 

  10. G Luo C Hofmann AL Bronckers M Sohocki A Bradley GBM Karsenty (1995) ArticleTitleP-7 is an inducer of nephrogenesis, and is also required for eye developement and skeletal patterning Genes Dev 9 2808–20 Occurrence Handle1:CAS:528:DyaK2MXpslOmtr4%3D Occurrence Handle7590255

    CAS  PubMed  Google Scholar 

  11. SN Wang J Lapage R Hirschberg (2001) ArticleTitleLoss of tubular bone morphogenetic protein-7 in diabetic nephropathy J Am Soc Nephrol 12 2392–9 Occurrence Handle1:CAS:528:DC%2BD3MXotl2lsrk%3D Occurrence Handle11675415

    CAS  PubMed  Google Scholar 

  12. S Vukicevic V Basic D Rogic N Basic MS Shih A Shepard et al. (1998) ArticleTitleOsteogenic protein-1 reduces severity of injury after ischemic acute renal failure in rat J Clin Invest 102 202–14 Occurrence Handle1:CAS:528:DyaK1cXktlWgsr4%3D Occurrence Handle9649574

    CAS  PubMed  Google Scholar 

  13. C Van Kooten AM Woltman MR Daha (2000) ArticleTitleImmunological function of tubular epithelial cells: the functional implications of CD40 expression Exp Nephrol 8 203–7 Occurrence Handle10.1159/000020669 Occurrence Handle1:CAS:528:DC%2BD3cXmsl2qtro%3D Occurrence Handle10940717

    Article  CAS  PubMed  Google Scholar 

  14. M Zeisberg C Bottiglio N Kumar Y Maeshima F Strutz GA Mueller et al. (2003) ArticleTitleBone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models Am J Physiol Renal Physiol 285 F1060–7 Occurrence Handle1:CAS:528:DC%2BD2cXhsV2j Occurrence Handle12915382

    CAS  PubMed  Google Scholar 

  15. S Wang Q Chen TC Simon F Strebeck L Chaudhary J Morrissey et al. (2003) ArticleTitleBone morphogenic protein-7, a novel therapy for diabetic nephropathy Kidney Int 63 2037–49 Occurrence Handle10.1046/j.1523-1755.2003.00035.x Occurrence Handle1:CAS:528:DC%2BD3sXkvVyiurY%3D Occurrence Handle12753291

    Article  CAS  PubMed  Google Scholar 

  16. KA Hruska G Guo M Wozniak D Martin S Miller H Liapis et al. (2000) ArticleTitleOsteogenic protein-1 prevents renal fibrogenesis associated with ureteral obstruction Am J Physiol Renal Physiol 279 F130–43 Occurrence Handle1:CAS:528:DC%2BD3cXltlyqt7c%3D Occurrence Handle10894795

    CAS  PubMed  Google Scholar 

  17. SE Gould M Day SS Jones HBM Dorai (2002) ArticleTitleP-7 regulates chemokine, cytokine, and hemodynamic gene expression in proximal tubule cells Kidney Int 61 51–60 Occurrence Handle10.1046/j.1523-1755.2002.00103.x Occurrence Handle1:CAS:528:DC%2BD38XlslGnsA%3D%3D Occurrence Handle11786084

    Article  CAS  PubMed  Google Scholar 

  18. K Miyazono K Kusanagi H Inoue (2001) ArticleTitleDivergence and convergence of TGF-beta/BMP signaling J Cell Physiol 187 265–76 Occurrence Handle10.1002/jcp.1080 Occurrence Handle1:CAS:528:DC%2BD3MXjtF2isbk%3D Occurrence Handle11319750

    Article  CAS  PubMed  Google Scholar 

  19. JA Oliver O Maarouf FH Cheema TP Martens Q Al-Awqati (2004) ArticleTitleThe renal papilla is a niche for adult kidney stem cells J Clin Invest 114 795–804 Occurrence Handle10.1172/JCI200420921 Occurrence Handle1:CAS:528:DC%2BD2cXnslWiurs%3D Occurrence Handle15372103

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Raghu Kalluri.

About this article

Cite this article

Okada, H., Kalluri, R. Recapitulation of kidney development paradigms by BMP-7 reverses chronic renal injury. Clin Exp Nephrol 9, 100–101 (2005). https://doi.org/10.1007/s10157-005-0360-0

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10157-005-0360-0

Key words

Navigation