Skip to main content

A case of Wegener’s granulomatosis with pulmonary bleeding successfully treated with double filtration plasmapheresis (DFPP)

Journal of Clinical and Experimental Nephrology volume 8, pages 369–374 (2004)Cite this article

Abstract

We report a case of a 41-year-old Japanese man who presented with rapidly progressive glomerulonephritis, chronic sinusitis, and positive cytoplasmic-antineutrophil cytoplasmic antibody (c-ANCA). Renal biopsy showed crescentic glomerulonephritis, and he was diagnosed as having Wegener’s granulomatosis. During the clinical course, he suffered from pulmonary bleeding, and combination therapy of steroid, immunosuppressant, and double filtration plasmapheresis (DFPP) was started. He rapidly entered remission after assistance through DFPP, suggesting the potential efficacy of DFPP for Wegener’s granulomatosis, especially with pulmonary bleeding.

This is a preview of subscription content, access via your institution.

Access options

Buy single article

Instant access to the full article PDF.

43,34 €

Price includes VAT (Finland)
Tax calculation will be finalised during checkout.

Author information

Affiliations

  1. Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine (A8), 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan

    Hirotsugu Iwatani

  2. Division of Nephrology, Osaka Rosai Hospital, Sakai, Osaka, Japan

    Hirotsugu Iwatani, Takashi Uzu, Masahiro Kakihara, Yuji Nakayama, Keizo Kanasaki, Masaya Yamato, Yasuhiro Hirai, Koichi Umimoto & Atsushi Yamauchi

Authors
  1. Hirotsugu Iwatani
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Takashi Uzu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Masahiro Kakihara
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Yuji Nakayama
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Keizo Kanasaki
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Masaya Yamato
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Yasuhiro Hirai
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Koichi Umimoto
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Atsushi Yamauchi
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Hirotsugu Iwatani.

About this article

Cite this article

Iwatani, H., Uzu, T., Kakihara, M. et al. A case of Wegener’s granulomatosis with pulmonary bleeding successfully treated with double filtration plasmapheresis (DFPP). Clin Exp Nephrol 8, 369–374 (2004). https://doi.org/10.1007/s10157-004-0321-z

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10157-004-0321-z

Key words

  • Wegener’s granulomatosis
  • Pulmonary bleeding
  • Double filtration plasmapheresis (DFPP)
  • Cytoplasmic-antineutrophil cytoplasmic antibody (c-ANCA)