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Pulmonary tuberculosis with atypical histopathological manifestations


This report presents a case of pulmonary tuberculosis with atypical histopathological manifestations in an immunocompetent patient. A 37-year-old Japanese man was admitted due to multiple small nodules on chest computed tomography (CT). He was diagnosed with pulmonary tuberculosis following a culture of acid-fast bacterium from suction sputum specimens obtained by bronchoscopy. The histopathological findings from video-assisted thoracoscopy revealed small, sporadically organized, and fibrotic lesions with infiltration of eosinophils, plasma cells, and lymphocytes. The administration of antitubercular drugs eliminated the abnormal shadows on chest CT. Extreme care must be taken in the diagnosis of a patient with inexplicable histopathological findings.

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Correspondence to Hirokazu Taniguchi.

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Taniguchi, H., Uchiyama, A., Shinno, H. et al. Pulmonary tuberculosis with atypical histopathological manifestations. J Infect Chemother 16, 350–352 (2010).

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  • Pulmonary tuberculosis
  • Pathology