Skip to main content

Advertisement

SpringerLink
Log in

Clinical characteristics and outcomes of bacteremia caused by Acinetobacter species other than A. baumannii: comparison with A. baumannii bacteremia

  • ORIGINAL ARTICLE
  • Published:
Journal of Infection and Chemotherapy

Abstract

Previous reports have suggested that bacteremia caused by Acinetobacter species other than A. baumannii is frequently associated with intravascular catheters, and that A. baumannii is less virulent than non-baumannii Acinetobacter. To validate these observations, 28 patients with bacteremia caused by Acinetobacter species other than A. baumannii (cases) were compared with 112 randomly selected patients with A. baumannii bacteremia (controls). Only 1/28 (3.6%) case episodes and 13/112 (11.6%) control episodes of bacteremia were definitely catheter-related (P = 0.301). Even if probable catheter-related episodes were included, the frequency did not differ significantly between cases and controls (46.4% vs 39.3%; P = 0.491). No significant differences between cases and controls were noted in crude mortality (17.9% vs 32.4%; P = 0.131) or bacteremia-related mortality (14.3% vs 12.6%; P = 0.760). In conclusion, we found that the portals of entry and the mortality of bacteremia associated with Acinetobacter species other than A. baumannii and with A. baumannii were similar.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. CM Beck-Sague WR Jarvis JH Brook DH Culver A Potts E Gay et al. (1990) ArticleTitleEpidemic bacteremia due to Acinetobacter baumannii in five intensive care units Am J Epidemiol 132 723–33 Occurrence Handle2403113 Occurrence Handle1:STN:280:DyaK3czos1WmtA%3D%3D

    PubMed  CAS  Google Scholar 

  2. H Seifert A Strate G Pulverer (1995) ArticleTitleNosocomial bacteremia due to Acinetobacter baumannii. Clinical features, epidemiology, and predictors of mortality Medicine (Baltimore) 74 340–9 Occurrence Handle10.1097/00005792-199511000-00004 Occurrence Handle1:STN:280:DyaK287gtFyisA%3D%3D

    Article  CAS  Google Scholar 

  3. JM Cisneros MJ Reyes J Pachon B Becerril FJ Caballero JL Garcia-Garmendia et al. (1996) ArticleTitleBacteremia due to Acinetobacter baumannii: epidemiology, clinical findings, and prognostic features Clin Infect Dis 22 1026–32 Occurrence Handle8783704 Occurrence Handle1:STN:280:DyaK28znsl2huw%3D%3D

    PubMed  CAS  Google Scholar 

  4. H Wisplinghoff W Perbix H Seifert (1999) ArticleTitleRisk factors for nosocomial bloodstream infections due to Acinetobacter baumannii: a case-control study of adult burn patients Clin Infect Dis 28 59–66 Occurrence Handle10028073 Occurrence Handle1:STN:280:DyaK1M7lt1equw%3D%3D

    PubMed  CAS  Google Scholar 

  5. H Wisplinghoff MB Edmond MA Pfaller RN Jones RP Wenzel H Seifert (2000) ArticleTitleNosocomial bloodstream infections caused by Acinetobacter species in United States hospitals: clinical features, molecular epidemiology, and antimicrobial susceptibility Clin Infect Dis 31 690–7 Occurrence Handle11017817 Occurrence Handle10.1086/314040 Occurrence Handle1:CAS:528:DC%2BD3cXotV2gsbY%3D

    Article  PubMed  CAS  Google Scholar 

  6. JL Garcia-Garmendia C Ortiz-Leyba J Garnacho-Montero J Garnacho-Montero FJ Jimenez-Jimenez C Perez-Paredes et al. (2001) ArticleTitleRisk factors for Acinetobacter baumannii nosocomial bacteremia in critically ill patients: a cohort study Clin Infect Dis 33 939–46 Occurrence Handle11528563 Occurrence Handle10.1086/322584 Occurrence Handle1:STN:280:DC%2BD3MvosFGrsw%3D%3D

    Article  PubMed  CAS  Google Scholar 

  7. J Koprnova I Svetlansky R Babel'a E Bilikova J Hanzen IJ Zuscakova et al. (2001) ArticleTitleProspective study of antibacterial susceptibility, risk factors and outcome of 157 episodes of Acinetobacter baumannii bacteremia in 1999 in Slovakia Scand J Infect Dis 33 891–5 Occurrence Handle11868760 Occurrence Handle10.1080/00365540110076688 Occurrence Handle1:STN:280:DC%2BD387jtlShtw%3D%3D

    Article  PubMed  CAS  Google Scholar 

  8. S Blot K Vandewoude F Colardyn (2003) ArticleTitleNosocomial bacteremia involving Acinetobacter baumannii in critically ill patients: a matched cohort study Intensive Care Med 29 471–5 Occurrence Handle12577148

    PubMed  Google Scholar 

  9. TK Ng JM Ling AF Cheng SR Norrby (1996) ArticleTitleA retrospective study of clinical characteristics of Acinetobacter bacteremia Scand J Infect Dis Suppl 101 26–32 Occurrence Handle9060049 Occurrence Handle1:STN:280:DyaK2s3htlartg%3D%3D

    PubMed  CAS  Google Scholar 

  10. J Gomez E Simarro V Banos L Requena J Ruiz F Garcia et al. (1999) ArticleTitleSix-year prospective study of risk and prognostic factors in patients with nosocomial sepsis caused by Acinetobacter baumannii Eur J Clin Microbiol Infect Dis 18 358–61 Occurrence Handle10421044 Occurrence Handle10.1007/PL00015019 Occurrence Handle1:STN:280:DyaK1MzksleqsQ%3D%3D

    Article  PubMed  CAS  Google Scholar 

  11. PJM Bouvet PAD Grimont (1986) ArticleTitleTaxonomy of the genus Acinetobacter with the recognition of Acinetobacter baumannii sp. nov., Acinetobacter haemolyticus sp. nov., Acinetobacter johnsonii sp. nov., and Acinetobacter junii sp. nov. and emended descriptions of Acinetobater calcoaceticus and Acinetobacter lwoffii Int J Syst Bacteriol 36 228–40 Occurrence Handle1:CAS:528:DyaL28Xit1Wqs7Y%3D Occurrence Handle10.1099/00207713-36-2-228

    Article  CAS  Google Scholar 

  12. PJ Bouvet PA Grimont (1987) ArticleTitleIdentification and biotyping of clinical isolates of Acinetobacter Ann Inst Pasteur Microbiol 138 569–78 Occurrence Handle3440090 Occurrence Handle10.1016/0769-2609(87)90042-1 Occurrence Handle1:STN:280:DyaL1c7kvF2itQ%3D%3D

    Article  PubMed  CAS  Google Scholar 

  13. PJ Bouvet S Jeanjean (1989) ArticleTitleDelineation of new proteolytic genomic species in the genusAcinetobacter Res Microbiol 140 291–9 Occurrence Handle2799067 Occurrence Handle10.1016/0923-2508(89)90021-1 Occurrence Handle1:STN:280:DyaK3c%2FhvVynsw%3D%3D

    Article  PubMed  CAS  Google Scholar 

  14. P Gerner-Smidt I Tjernberg J Ursing (1991) ArticleTitleReliability of phenotypic tests for identification of Acinetobacter species J Clin Microbiol 29 277–82 Occurrence Handle2007635 Occurrence Handle1:STN:280:DyaK3M7nvVSnuw%3D%3D

    PubMed  CAS  Google Scholar 

  15. H Seifert A Strate A Schulze G Pulverer (1994) ArticleTitleBacteremia due to Acinetobacter species other than Acinetobacter baumannii Infection 22 379–85 Occurrence Handle7698833 Occurrence Handle10.1007/BF01715492 Occurrence Handle1:STN:280:DyaK2M3htlWjug%3D%3D

    Article  PubMed  CAS  Google Scholar 

  16. SC Ku PR Hsueh PC Yang KT Luh (2000) ArticleTitleClinical and microbiological characteristics of bacteremia caused by Acinetobacter lwoffii Eur J Clin Microbiol Infect Dis 19 501–5 Occurrence Handle10968320 Occurrence Handle10.1007/s100960000315 Occurrence Handle1:STN:280:DC%2BD3M%2Flt1OntA%3D%3D

    Article  PubMed  CAS  Google Scholar 

  17. WR McCabe GG Jackson (1962) ArticleTitleGram-negative bacteremia I Arch Intern Med 110 847–55

    Google Scholar 

  18. RC Bone WJ Sibbald CL Sprung (1992) ArticleTitleThe ACCP-SCCM consensus conference on sepsis and organ failure Chest 101 1481–3 Occurrence Handle1600757 Occurrence Handle1:STN:280:DyaK383ovFartA%3D%3D

    PubMed  CAS  Google Scholar 

  19. JW Chow MJ Fine DM Shlaes JP Quinn DC Hooper MP Johnson et al. (1991) ArticleTitleEnterobacter bacteremia: clinical features and emergence of antibiotic resistance during therapy Ann Intern Med 115 585–90 Occurrence Handle1892329 Occurrence Handle1:STN:280:DyaK3MzmvFWhsw%3D%3D

    PubMed  CAS  Google Scholar 

  20. TP Lodise PS McKinnon VH Tam MJ Rybak (2002) ArticleTitleClinical outcomes for patients with bacteremia caused by vancomycin-resistant enterococcus in a level 1 trauma center Clin Infect Dis 34 922–9 Occurrence Handle11880957 Occurrence Handle10.1086/339211

    Article  PubMed  Google Scholar 

  21. DG Maki CE Weise HW Sarafin (1977) ArticleTitleA semiquantitative culture method for identifying intravenous-catheter-related infection N Engl J Med 296 1305–9 Occurrence Handle323710 Occurrence Handle1:STN:280:DyaE2s7ntFSntA%3D%3D Occurrence Handle10.1056/NEJM197706092962301

    Article  PubMed  CAS  Google Scholar 

  22. InstitutionalAuthorNameNational Committee for Clinical Laboratory Standards (2002) Performance standard for antimicrobial susceptibility testing: ninth informational supplement M100-S9 NCCLS Wayne, PA

    Google Scholar 

  23. II Raad GP Bodey (1992) ArticleTitleInfectious complications of indwelling vascular catheters Clin Infect Dis 15 197–208 Occurrence Handle1520756 Occurrence Handle1:STN:280:DyaK38zpt12ntg%3D%3D

    PubMed  CAS  Google Scholar 

  24. PA Tilley FJ Roberts (1994) ArticleTitleBacteremia with Acinetobacter species: risk factors and prognosis in different clinical settings Clin Infect Dis 18 896–900 Occurrence Handle8086549 Occurrence Handle1:STN:280:DyaK2czmvV2nuw%3D%3D

    PubMed  CAS  Google Scholar 

  25. H Seifert R Baginski A Schulze G Pulverer (1993) ArticleTitleThe distribution of Acinetobacter species in clinical culture materials Zentralbl Bakteriol 279 544–52 Occurrence Handle8305812 Occurrence Handle1:STN:280:DyaK2c7jvVWksg%3D%3D

    PubMed  CAS  Google Scholar 

  26. H Siau KY Yuen PL Ho SS Wong PC Woo (1999) ArticleTitleAcinetobacter bacteremia in Hong Kong: prospective study and review Clin Infect Dis 28 26–30 Occurrence Handle10028065 Occurrence Handle1:STN:280:DyaK1M7lt1eqsw%3D%3D

    PubMed  CAS  Google Scholar 

  27. DH Forster FD Daschner (1998) ArticleTitleAcinetobacter species as nosocomial pathogens Eur J Clin Microbiol Infect Dis 17 73–7 Occurrence Handle9629969 Occurrence Handle1:STN:280:DyaK1c3ptF2hsw%3D%3D

    PubMed  CAS  Google Scholar 

  28. H Seifert L Dijkshoorn P Gerner-Smidt N Pelzer I Tjernberg M Vaneechoutte (1997) ArticleTitleDistribution of Acinetobacter species on human skin: comparison of phenotypic and genotypic identification methods J Clin Microbiol 35 2819–25 Occurrence Handle9350741 Occurrence Handle1:CAS:528:DyaK2sXnt1ejtb0%3D

    PubMed  CAS  Google Scholar 

  29. M Vaneechoutte L Dijkshoom I Tjernberg A Elaichouni P de Vos G Claeys et al. (1995) ArticleTitleIdentification of Acinetobacter genomic species by amplified ribosomal DNA restriction analysis J Clin Microbiol 33 11–5 Occurrence Handle7699025 Occurrence Handle1:CAS:528:DyaK2MXjsVGnsr8%3D

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Center for Antimicrobial Resistance and Microbial Genetics, 388-1 Pungnap-dong, Songpa-gu, Seoul, 138-736, Republic of Korea

    Sang-Ho Choi, Mi-Young Kim, Jae-Bum Jun, Nam Joong Kim, Jin-Yong Jeong, Yang Soo Kim & Jun Hee Woo

  2. Division of Infectious Diseases, Soonchunhyang University Hospital, Bucheon, Republic of Korea

    Eun Ju Choo

  3. Department of Internal Medicine, Inje University College of Medicine, Ilsan, Republic of Korea

    Yee Gyung Kwak

  4. Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

    Mi-Na Kim

Authors
  1. Sang-Ho Choi
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Eun Ju Choo
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yee Gyung Kwak
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Mi-Young Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Jae-Bum Jun
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Mi-Na Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Nam Joong Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Jin-Yong Jeong
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Yang Soo Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Jun Hee Woo
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Nam Joong Kim.

About this article

Cite this article

Choi, SH., Choo, E., Kwak, Y. et al. Clinical characteristics and outcomes of bacteremia caused by Acinetobacter species other than A. baumannii: comparison with A. baumannii bacteremia. J Infect Chemother 12, 380–386 (2006). https://doi.org/10.1007/s10156-006-0488-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10156-006-0488-1

Key words

Search

Navigation