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Bacteremic and leukopenic pneumococcal pneumonia: successful treatment with antibiotics, pulse steroid, and continuous hemodiafiltration

Abstract

We describe a case of bacteremic, leukopenic pneumococcal pneumonia with respiratory failure, accompanied by diabetic ketoacidosis and hypothermia. Pulmonary leukostasis may play a role in the pathogenesis of the acute respiratory distress syndrome (ARDS) in pneumococcal pneumonia. The patient recovered with mechanical ventilation, intravenous antibiotics, pulse-steroid therapy, and continuous hemodiafiltration (CHDF). In particular, administration of steroid and the use of CHDF may improve the status of pulmonary leukostasis in leukopenic pneumococcal infection.

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Received: October 22, 2001 / Accepted: March 14, 2002

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Yokoyama, T., Sakamoto, T., Shida, N. et al. Bacteremic and leukopenic pneumococcal pneumonia: successful treatment with antibiotics, pulse steroid, and continuous hemodiafiltration. J Infect Chemother 8, 247–251 (2002). https://doi.org/10.1007/s10156-002-0173-y

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  • DOI: https://doi.org/10.1007/s10156-002-0173-y

  • Key words Streptococcus pneumoniae Pneumococcal pneumonia Pulmonary leukostasis Leukopenia Steroid pulse therapy Continuous hemodiafiltration