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Midterm functional results of taTME with neuromapping for low rectal cancer

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Abstract

Background

Information on functional outcomes after laparoscopic-assisted transanal total mesorectal excision (taTME) is limited. This study analyzed the functional results in patients with low rectal cancer.

Methods

Ten consecutive patients (nine males) undergoing electrophysiologically controlled nerve-sparing taTME were investigated prospectively and asked to complete functional questionnaires [the International Prostate Symptom Score (IPSS), International Index of Erectile Function, Female Sexual Function Index, Wexner score, and low anterior resection syndrome (LARS) score]. Bladder function was also assessed according to residual urine volume. Preoperative function was compared to the functional outcome 3 and 6 months, and 9 months if eligible, after stoma closure or surgery in the absence of a diverting stoma.

Results

Prior to therapy, urinary and sexual function was impaired in 40 and 60 % of patients, respectively. None of the patients developed pathological residual urine volumes after at least unilateral functional pelvic nerve-sparing. Median IPSS was lower than preoperative scores (p > 0.05). Two males with incomplete nerve preservation were considered impotent during a median follow-up of 15 months (range 6–20 months). The female was judged to be sexually inactive. The median Wexner score was 1 (range 0–7) prior to any therapy and increased to 7 (range 0–15) at 6 months (p = 0.029), with 40 % of patients categorized as having no LARS and 50 % minor LARS. The median LARS score was 28 (range 9–38) at 3 months and 26 (range 9–32) at 6 months (p = 0.165).

Conclusions

Despite a small sample size and confounding factors, data indicate that taTME has the potential to preserve continence, sufficient bowel function, and urogenital function.

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Acknowledgments

The authors would like to thank Dr. Ursula Gönner for fruitful discussions and psycho-oncological support of our patients.

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Correspondence to W. Kneist.

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The authors declare that they have no conflict of interest.

Ethical approval

The study has been performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments.

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Informed consent was obtained from all individual participants included in the study.

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Kneist, W., Wachter, N., Paschold, M. et al. Midterm functional results of taTME with neuromapping for low rectal cancer. Tech Coloproctol 20, 41–49 (2016). https://doi.org/10.1007/s10151-015-1390-6

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  • DOI: https://doi.org/10.1007/s10151-015-1390-6

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