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Uterine smooth muscle tumors of uncertain malignant potential: a case presentation

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Abstract

A 42-year-old virgin woman was admitted to our clinic with increasing menorrhagia and dysmenorrhea for several months. A pelvic ultrasound scan showed a 9 × 7 cm heterogeneous mass in the uterine cavity. Pelvic magnetic resonance imaging showed a large non-homogeneous tumor mass measuring 97 × 56 mm in the uterine cavity. After intravenous contrast material, cystic necrotic areas with marked contrast enhancement were observed in the solid lesion. Tumor markers were all within normal ranges. The patient underwent laparotomy, and total hysterectomy and bilateral salpingo-oophorectomy were performed. Our case was diagnosed as uterine smooth muscle tumor of uncertain malignant potential (STUMP). The patient was put on a close clinical follow-up schedule, and is doing well without recurrence in 2 years later. Patients with STUMP should be counseled regarding the potential for recurrence as leiomyosarcoma, and may require closer surveillance than a yearly examination and may need a consultation with a gynecologic oncologist.

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References

  1. Guntupalli SR, Ramirez PT, Anderson ML et al (2009) Uterine smooth muscle tumor of uncertain malignant potential: a retrospective analysis. Gynecol Oncol 113(3):324–326

    Article  PubMed  Google Scholar 

  2. D’Angelo E, Prat J (2010) Uterine sarcomas: a review. Gynecol Oncol 116(1):131–139

    Article  PubMed  Google Scholar 

  3. Bell SW, Kempson RL, Hendrickson MR (1994) Problematic uterine smooth muscle neoplasms—a clinicopathological study of 213 cases. Am J Surg Pathol 18:535–558

    Article  PubMed  CAS  Google Scholar 

  4. Slik K, El Rishi F, Bulugma M (2009) Uterine smooth muscle tumors: clinicopathological evaluation. Free communication oral presentations. Int J Gynecol Obstet 107(S2):S93–S396

    Google Scholar 

  5. Gökaslan H, Pekin T, Ay E et al (2004) Smooth muscle tumors of the uterus. T Klin J Gynecol Obst 14:27–31

    Google Scholar 

  6. Shapiro A, Ferenczy A, Turcotte R et al (2004) Uterine smooth-muscle tumor of uncertain malignant potential metastasizing to the humerus as a high-grade leiomyosarcoma. Gynecol Oncol 94(3):818–820

    Article  PubMed  Google Scholar 

  7. Mittal K, Demopouos RI (2001) MIB-1 (Ki-67), p53, estrogen receptor, and progesterone receptor expression in uterine smooth muscle tumors. Hum Pathol 32(9):984–987

    Article  PubMed  CAS  Google Scholar 

  8. Peters WA, Howard DR, Andersen WA et al (1994) Uterine smooth-muscle tumors of uncertain malignant potential. Obstet Gynecol 83:1015–1020

    Article  PubMed  Google Scholar 

  9. Ng JS, Han A, Chew SH et al (2010) A clinicopathologic study of uterine smooth muscle tumours of uncertain malignant potential (STUMP). Ann Acad Med Singapore 39(8):625–628

    PubMed  Google Scholar 

  10. Berretta R, Rolla M, Merisio C et al (2008) Uterine smooth muscle tumor of uncertain malignant potential: a three-case report. Int J Gynecol Cancer 18(5):1121–1126

    Article  PubMed  CAS  Google Scholar 

  11. Al-Nafussi A (2004) Uterine smooth-muscle tumours: practical approach to diagnosis. Curr Diagn Pathol 10:140–156

    Article  Google Scholar 

Download references

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Correspondence to Kazım Gezginç.

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Gezginç, K., Yazici, F. & Tavli, L. Uterine smooth muscle tumors of uncertain malignant potential: a case presentation. Int J Clin Oncol 16, 592–595 (2011). https://doi.org/10.1007/s10147-010-0172-4

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  • DOI: https://doi.org/10.1007/s10147-010-0172-4

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