Abstract
Primary sarcoma of the fallopian tube is a very rare neoplasm. We report the case of a 69-year-old woman affected with leiomyosarcoma of the left fallopian tube. Her chief complaint was lower abdominal pain. The preoperative diagnosis was a left adnexal malignant tumor based on pelvic examination, abdominal computed tomography, and magnetic resonance imaging. Following a laparotomy, she was ultimately diagnosed with a FIGO IIc fallopian tube leiomyosarcoma. She was treated with total abdominal hysterectomy, bilateral salpingo-oophorectomy, pelvic lymph node dissection, partial omentectomy, and low anterior resection for rectal invasion. The patient subsequently received adjuvant chemotherapy with pirarubicin and ifosfamide. Thirty months after the first therapy, a computed tomography scan revealed metastasis of the liver, lung, and supraclavicular lymph node. The patient died of the disease 39 months after the initial treatment.
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References
Scully RE, Yung RH, Clement PB (1998) Tumors of the ovary, mal-developed gonads, fallopian tube, and broad ligament. In: Rosai JR, Sobin LH (eds) Atlas of tumor pathology, 3rd series, fascicle 23. Armed Forces Institute of Pathology, Washington D.C., pp 51–168
Pettersson F (1992) Staging rules for gestational trophoblastic tumor and fallopian tube cancer. Acta Obstet Gynecol Scand 71:224–225
Senger E (1886) Ueber ein primaeres Sarkom der Tuben. Centralbl F Gynaek 10:601–604
Jacoby AF, Fuller AF Jr, Thor AD et al (1993) Primary leiomyosarcoma of the fallopian tube. Gynecol Oncol 51(3):404–407
Köhler U, Horn LC, Marzotko E et al (1997) Primary dedifferentiated leiomyosarcoma of the fallopian tube. Zentralbl Gynakol 119(5):237–240
Mariani L, Quattrini M, Galati M et al (2005) Primary leiomyosarcoma of the fallopian tube: a case report. Eur J Gynaecol Oncol 26(3):33–35
Abrams J, KAzal HL, Hobbs RE (1958) Primary sarcoma of the Fallopian tube: review of the literature and report of one case. Am J Obstet Gynecol 75(1):180–182
Foster R, Solano S, Mahoney J et al (2006) Reclassification of a tubal leiomyosarcoma as an eGIST by molecular evaluation of c-KIT. Gynecol Oncol 101:363–366
O’Sullivan PJ, Harris AC, Munk PL (2008) Radiological imaging features of non-uterine leiyomosarcoma. Br J Radiol 81(961):73–81
Blaikley JB (1973) Sarcoma of the fallopian tube. J Obstet Gynaecol Br Commonw 80:759–760
Giuntoli RL, Metzinger DS, DiMarco CS et al (2003) Retrospective review of 208 patients with leiomyosarcoma of the uterus; prognostic indicators, surgical management, and adjuvant chemotherapy. Gynecol Oncol 89:460–469
Raaf JH (1993) Soft tissue sarcomas: diagnosis and treatment. Mosby, St. Louis
Omura GA, Major FJ, Blessing JA et al (1983) A randomized study of adriamycin with and without dimethyl triazenolimidazole carboxamide in advanced uterine sarcomas. Cancer 52:626–632
Maurel J, Fra J, Lopez-Pousa A et al (2004) Sequential dose-dense doxorubicin and ifosfamide for advanced soft tissue sarcomas: a Phase II trial by the Spanish Group for Research on Sarcomas (GEIS). Cancer 100(7):1498–1506
Currie JL, Blessing JA, Hyman B et al (1996) Combination chemotherapy with hydroxyurea, dacarbazine (DTIC), and etoposide in the treatment of uterine leiomyosarcoma: a Gynecologic Oncology Group study. Gynecol Oncol 61(1):27–30
Hensley ML, Blessing JA, Degeest K et al (2008) Fixed-dose rate gemcitabine plus docetaxel as first-line therapy for metastatic uterine leiomyosarcoma: a Gynecologic Oncology Group phase II trial. Gynecol Oncol 109:329–334
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Ueda, T., Emoto, M., Fukuoka, M. et al. Primary leiomyosarcoma of the fallopian tube. Int J Clin Oncol 15, 206–209 (2010). https://doi.org/10.1007/s10147-010-0027-z
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DOI: https://doi.org/10.1007/s10147-010-0027-z