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Stereotactic radiosurgery for management of vestibular schwannoma: a short review

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Abstract

Management options for newly diagnosed vestibular schwannoma (VS) include observation, surgery, or radiation. There are no randomized trials to guide management of patients with VS. This article is a short review of the role of stereotactic radiosurgery in management of newly diagnosed VS.

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References

  1. Breivik CN, Nilsen RM, Myrseth E, Pedersen PH, Varughese JK, Chaudhry AA et al (2013) Conservative management or gamma knife radiosurgery for vestibular schwannoma: tumor growth, symptoms, and quality of life. Neurosurgery. 73(1):48–56 discussion 56-57

    Article  Google Scholar 

  2. Carlson ML, Link MJ, Wanna GB, Driscoll CLW (2015) Management of sporadic vestibular schwannoma. Otolaryngol Clin N Am 48(3):407–422

    Article  Google Scholar 

  3. Chao ST, Thakkar VV, Barnett GH, Vogelbaum MA, Angelov L, Weil RJ, Rasmussen P, Reuther AM, Jamison B, Neyman G, Suh JH (2012) Prospective study of the short-term adverse effects of gamma knife radiosurgery. Technol Cancer Res Treat 11(2):117–122

    Article  Google Scholar 

  4. Chopra R, Kondziolka D, Niranjan A, Lunsford LD, Flickinger JC (2007) Long-term follow-up of acoustic schwannoma radiosurgery with marginal tumor doses of 12 to 13 Gy. Int J Radiat Oncol Biol Phys 68(3):845–851

    Article  Google Scholar 

  5. Chung W-Y, Liu K-D, Shiau C-Y, Wu H-M, Wang L-W, Guo W-Y et al (2005) Gamma knife surgery for vestibular schwannoma: 10-year experience of 195 cases. J Neurosurg 102(Suppl):87–96

    Article  Google Scholar 

  6. Di Maio S, Akagami R (2009) Prospective comparison of quality of life before and after observation, radiation, or surgery for vestibular schwannomas. JNS. 111(4):855–862

    Article  Google Scholar 

  7. Foote KD, Friedman WA, Buatti JM, Meeks SL, Bova FJ, Kubilis PS (2001) Analysis of risk factors associated with radiosurgery for vestibular schwannoma. J Neurosurg 95(3):440–449

    Article  CAS  Google Scholar 

  8. Golfinos JG, Hill TC, Rokosh R, Choudhry O, Shinseki M, Mansouri A et al (2016) A matched cohort comparison of clinical outcomes following microsurgical resection or stereotactic radiosurgery for patients with small- and medium-sized vestibular schwannomas. JNS. 125(6):1472–1482

    Article  Google Scholar 

  9. Gormley WB, Sekhar LN, Wright DC, Kamerer D, Schessel D (1997) Acoustic neuromas: results of current surgical management. Neurosurgery. 41(1):50–58 discussion 58-60

    Article  CAS  Google Scholar 

  10. Hansasuta A, Choi CYH, Gibbs IC, Soltys SG, Tse VCK, Lieberson RE, Hayden MG, Sakamoto GT, Harsh GR 4th, Adler JR Jr, Chang SD (2011) Multisession stereotactic radiosurgery for vestibular schwannomas: single-institution experience with 383 cases. Neurosurgery. 69(6):1200–1209

    Article  Google Scholar 

  11. Haque R, Wojtasiewicz TJ, Gigante PR, Attiah MA, Huang B, Isaacson SR et al (2011) Efficacy of facial nerve–sparing approach in patients with vestibular schwannomas. JNS. 115(5):917–923

    Article  Google Scholar 

  12. Kano H, Kondziolka D, Khan A, Flickinger JC, Lunsford LD (2009) Predictors of hearing preservation after stereotactic radiosurgery for acoustic neuroma. J Neurosurg 111(4):863–873

    Article  Google Scholar 

  13. Kim K-M, Park C-K, Chung H-T, Paek SH, Jung H-W, Kim DG (2007) Long-term outcomes of gamma knife stereotactic radiosurgery of vestibular schwannomas. J Korean Neurosurg Soc 42(4):286–292

    Article  Google Scholar 

  14. Klijn S, Verheul JB, Beute GN, Leenstra S, Mulder JJS, Kunst HPM, Hanssens PE (2016) Gamma knife radiosurgery for vestibular schwannomas: evaluation of tumor control and its predictors in a large patient cohort in the Netherlands. J Neurosurg 124(6):1619–1626

    Article  Google Scholar 

  15. Kondziolka D, Lunsford LD, McLaughlin MR, Flickinger JC (1998) Long-term outcomes after radiosurgery for acoustic neuromas. N Engl J Med 339(20):1426–1433

    Article  CAS  Google Scholar 

  16. Kondziolka D, Mousavi SH, Kano H, Flickinger JC, Lunsford LD (2012) The newly diagnosed vestibular schwannoma: radiosurgery, resection, or observation? Neurosurg Focus 33(3):E8

    Article  Google Scholar 

  17. Leksell L (1971) A note on the treatment of acoustic tumours. Acta Chir Scand 137(8):763–765

    CAS  PubMed  Google Scholar 

  18. Link MJ, Driscoll CLW, Foote RL, Pollock BE (2012) Radiation therapy and radiosurgery for vestibular schwannomas. Otolaryngol Clin N Am 45(2):353–366

    Article  Google Scholar 

  19. Litvack ZN, Norén G, Chougule PB, Zheng Z (2003) Preservation of functional hearing after gamma knife surgery for VS. Neurosurg Focus 14(5):e3

    Article  Google Scholar 

  20. Lunsford LD, Niranjan A, Flickinger JC et al (2005) Radiosurgery of vestibular schwannomas: summary of experience in 829 cases. J Neurosurg 102:195–199

    Article  Google Scholar 

  21. Meijer OWM, Vandertop WP, Baayen JC, Slotman BJ (2003) Single-fraction vs. fractionated linac-based stereotactic radiosurgery for VS: a single-institution study. Int J Radiat Oncol Biol Phys 56(5):1390–1396

    Article  CAS  Google Scholar 

  22. Mulkens TH, Parizel PM, Martin JJ, Degryse HR, Van de Heyning PH, Forton GE et al (1993) Acoustic schwannoma: MR findings in 84 tumors. Am J Roentgenol 160(2):395–398

    Article  CAS  Google Scholar 

  23. Murphy ES, Barnett GH, Vogelbaum MA, Neyman G, Stevens GHJ, Cohen BH, Elson P, Vassil AD, Suh JH (2011) Long-term outcomes of gamma knife radiosurgery in patients with vestibular schwannomas. J Neurosurg 114(2):432–440

    Article  Google Scholar 

  24. Muzevic D, Legcevic J, Splavski B, Cayé-Thomasen P (2014) Stereotactic radiotherapy for vestibular schwannoma. Cochrane ENT Group, editor. Cochrane Database Syst Rev [Internet] [cited 2019 Sept 25]; Available from: http://doi.wiley.com/10.1002/14651858.CD009897.pub2

  25. Myrseth E, Møller P, Pedersen PH, Lund-Johansen M (2009) Vestibular schwannoma: surgery or gamma knife radiosurgery? A prospective, nonrandomized study. Neurosurgery 64(4):654–663

    Article  Google Scholar 

  26. Pollock BE, Link MJ, Foote RL (2009) Failure rate of contemporary low-dose radiosurgical technique for vestibular schwannoma. J Neurosurg 111(4):840–844

    Article  Google Scholar 

  27. Pollock BE, Driscoll CL, Foote RL et al (2006) Patient outcomes after vestibular schwannoma management: a prospective comparison of microsurgical resection and stereotactic radiosurgery. Neurosurgery. 59:77–85 discussion 77-85

    Article  Google Scholar 

  28. Régis J, Tamura M, Delsanti C, Roche P-H, Pellet W, Thomassin J-M (2008) Hearing preservation in patients with unilateral vestibular schwannoma after gamma knife surgery. Prog Neurol Surg 21:142–151

    Article  Google Scholar 

  29. Saadatmand HJ, Wu C-C, Wang TJC (2016) Interdisciplinary management of acoustic neuromas. Appl Radiat Oncol 5(1):5–16

  30. Schnurman Z, Nakamura A, McQuinn MW, Golfinos JG, Roland JT, Kondziolka D (2019) Volumetric growth rates of untreated vestibular schwannomas. J Neurosurg 2:1–7

    Google Scholar 

  31. Smith DR, Saadatmand HJ, Wu C-C, Black PJ, Wuu Y-R, Lesser J, Horan M, Isaacson SR, Wang TJC, Sisti MB (2019) Treatment outcomes and dose rate effects following gamma knife stereotactic radiosurgery for vestibular schwannomas. Neurosurgery. 85(6):E1084–E1094

    Article  Google Scholar 

  32. Timmer FCA, Hanssens PEJ, van Haren AE, van Overbeeke JJ, Mulder JJS, Cremers CWRJ, Graamans K (2011) Follow-up after gamma knife radiosurgery for vestibular schwannomas: volumetric and axial control rates. Laryngoscope. 121(7):1359–1366

    Article  Google Scholar 

  33. Tsao MN, Sahgal A, Xu W, De Salles A, Hayashi M, Levivier M et al (2017) Stereotactic radiosurgery for vestibular schwannoma: International Stereotactic Radiosurgery Society (ISRS) practice guideline. J Radiosurg SBRT 5(1):5–24

    PubMed  PubMed Central  Google Scholar 

  34. Vulpe H, Save AV, Xu Y, Elliston CD, Garrett MD, Wu C-C et al (2019) Frameless stereotactic radiosurgery on the gamma knife icon: early experience from 100 patients. Neurosurgery https://doi.org/10.1093/neuros/nyz227

  35. Williams JA (2002) Fractionated stereotactic radiotherapy for acoustic neuromas. Acta Neurochir 144(12):1249–1254 discussion 1254

    Article  CAS  Google Scholar 

  36. Yang I, Sughrue ME, Han SJ, Aranda D, Pitts LH, Cheung SW et al (2010) A comprehensive analysis of hearing preservation after radiosurgery for vestibular schwannoma. J Neurosurg 112(4):851–859

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Radiation Oncology, Columbia University Irving Medical Center, New York, NY, USA

    Elizabeth J. Buss, Tony J. C. Wang & Michael B. Sisti

  2. Herbert Irving Comprehensive Cancer Center, NewYork-Presbyterian/Columbia University Irving Medical Center, New York, NY, USA

    Tony J. C. Wang & Michael B. Sisti

  3. Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA

    Tony J. C. Wang & Michael B. Sisti

  4. Department of Otolaryngology/Head and Neck Surgery, Columbia University Irving Medical Center, New York, NY, USA

    Michael B. Sisti

Authors
  1. Elizabeth J. Buss
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Correspondence to Tony J. C. Wang.

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Conflict of interest

Dr. Wang reports personal fees and non-financial support from AbbVie, personal fees from AstraZeneca, personal fees from Cancer Panels, personal fees from Doximity, personal fees and non-financial support from Elekta, personal fees and non-financial support from Merck, personal fees and non-financial support from Novocure, personal fees and non-financial support from RTOG Foundation, personal fees from Rutgers, personal fees from University of Iowa, personal fees from Wolters Kluwer, outside the submitted work.

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Buss, E.J., Wang, T.J.C. & Sisti, M.B. Stereotactic radiosurgery for management of vestibular schwannoma: a short review. Neurosurg Rev 44, 901–904 (2021). https://doi.org/10.1007/s10143-020-01279-2

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  • DOI: https://doi.org/10.1007/s10143-020-01279-2

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