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Samii M, Gerganov VM, Freund HJ, Hannover, Germany
Dr. Rismanchi discussed some interesting aspects in his Letter to the Editor that extend the interpretation provided in our article and touch upon some relevant issues. He also reinforce our intention to find a more specific electrophysiological and structural “signature” that allows for identifying the maladaptive and dysfunctional zones usually located outside the particular lesion such as tumors or vascular malformations. It will be interesting to see whether the upcoming empirical evidence will meet the author’s arguments.
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Rismanchi, M. Toward restorative neurosurgery at cortical level: the role of injured primitive networks in upsetting perilesional reorganization. Neurosurg Rev 36, 503–504 (2013). https://doi.org/10.1007/s10143-013-0466-x
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DOI: https://doi.org/10.1007/s10143-013-0466-x