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Dermoid lesion of the cavernous sinus: case report and review of the literature

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Intracranial dermoids are rare congenital tumors. Supratentorial dermoid cysts were more frequently reported in the last decade, and they are known to have a predilection for the cavernous sinus. Interdurally localized dermoids presenting with ophthalmoplegia is uncommon. Previously, the association of dermoid lesions with the cavernous sinus and the complexity of the operative procedure were emphasized only by a few authors. We report a case of a dermoid cyst that was embedded fully in the cavernous sinus and review the related cavernous dermoid lesions in the literature. Fronto-orbitozygomatic craniotomy was performed, and despite adherence of the tough capsule to the cranial nerves, the lesion was grossly removed in total. The patient was doing well 1 year after the operation, and there was no recurrence of signs and symptoms. Interdural growth of cavernous dermoid tumors must be considered, and careful evaluation of preoperative computed tomography and magnetic resonance images aids in making the decision concerning the operative approach. Upon review of the literature, we detected only eight similar cases concerning cavernous dermoid cysts. Although total excision of these cavernous lesions has been reported previously, we believe that total excision can sometimes be hazardous and not feasible.

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  1. Alvord EC Jr (1977) Growth rates of epidermoid tumors. Ann Neurol 2:367–370

    PubMed  Google Scholar 

  2. Baxter JW, Netsky MG (1985) Epidermoid and dermoid tumors: pathology. In: Wilkins RH, Rengachary SS (eds) Neurosurgery, vol 1. McGraw-Hill, New York, pp 655–661

  3. Conley FK (1985) Epidermoid and dermoid tumors: clinical features and surgical management. In: Wilkins RH, Rengachary SS (eds) Neurosurgery, vol 1. McGraw-Hill, New York, pp 668–673

  4. Arseni C, Danaila L, Constantinescu AI, Carp N, Decu P (1976) Cerebral dermoid tumors. Neurochirurgia 19:104–114

    CAS  PubMed  Google Scholar 

  5. Rubin G, Scienza R, Pasqualin A, Rosta L, Da Pian R (1989) Craniocerebral epidermoids and dermoids. Acta Neurochir (Wien) 97:1–16

    Google Scholar 

  6. Yaşargil MG, Abernathey CD, Sarioglu AÇ (1989) Microneurosurgical treatment of intracranial dermoid and epidermoid tumors. Neurosurgery 24:561–567

    PubMed  Google Scholar 

  7. Abdelouafi A, Ousehal A, Gharbi A, Ait Benali S, El Kamar A, Kadiri R (2000) Cavernous sinus dermoid cyst with unusual parapharyngeal development. J Neuroradiol 27:140–143

    CAS  PubMed  Google Scholar 

  8. DeMonte F, Al-Mefty O (1992) Ruptured dermoid tumor of the cavernous sinus associated with the syndrome of fat embolism: case report. J Neurosurg 77:312–315

    CAS  PubMed  Google Scholar 

  9. Lunardi P, Missori P (1991) Supratentorial dermoid cysts. J Neurosurg 75:262–266

    CAS  PubMed  Google Scholar 

  10. Nakagawa K, Ohno K, Nojiri T, Hirakawa K (1997) Interdural dermoid cyst of the cavernous sinus presenting with oculomotor palsy: case report (Abstract) (Jpn). No Shinkei Geka 25:847–851

    CAS  PubMed  Google Scholar 

  11. North KN, Anthony JH, Johnston IH (1993) Dermoid of cavernous sinus resulting in isolated oculomotor nerve palsy. Pediatr Neurol 9:221–223

    CAS  PubMed  Google Scholar 

  12. Chen Y-F, Liu H-M, Tu Y-K (2003) Dermoid cyst as a dumbbell-shaped tumour of the cavernous sinus. Pediatr Radiol 33:72

    Article  PubMed  Google Scholar 

  13. Guidetti B, Gagliardi FM (1977) Epidermoid and dermoid cysts. Clinical evaluation and late surgical results. J Neurosurg 47:12–18

    CAS  PubMed  Google Scholar 

  14. Caldarelli M, Colosimo C, Di Rocco C (2001) Intra-axial dermoid/epidermoid tumors of the brainstem in children. Pediatr Neurosurg 56:97–105

    Article  CAS  Google Scholar 

  15. Miller NR (1977) Solitary oculomotor nerve palsy in childhood. Am J Ophthalmol 83:106–111

    CAS  PubMed  Google Scholar 

  16. Mori K, Handa H, Moritake K, Takeuchi J, Nakano Y (1982) Suprasellar epidermoid. Neurochirurgia 25:138–142

    CAS  PubMed  Google Scholar 

  17. Mac Carty CS, Leavens ME, Love JG, Kernohan JW (1959) Dermoid and epidermoid tumors in the central nervous system of adults. Surg Neurol Obstet 108:191–198

    Google Scholar 

  18. Messori A, Polonara G, Serio A, Gambelli E, Salvolini U (2002) Expanding experience with spontaneous dermoid rupture in the MRI era: diagnosis and follow-up. Eur J Radiol 43:19–27

    Article  PubMed  Google Scholar 

  19. Hamer J (1980) Diagnosis by computerized tomography of intradural dermoid with spontaneous rupture of the cyst. Acta Neurochir (Wien) 51:219–226

    Google Scholar 

  20. Gormley WB, Tomecek FJ, Qureshi N, Malik GM (1994) Craniocerebral epidermoid and dermoid tumors: a review of 32 cases. Acta Neurochir (Wien) 128:115–121

    Google Scholar 

  21. Wilms G, Casselman J, Demaerel Ph, Plets C, De Haene I, Baert AH (1991) CT and MRI of ruptured intracranial dermoids. Neuroradiology 33:149–151

    CAS  PubMed  Google Scholar 

  22. Kehrly P, Maillot CL, Wolff Quenot MJ (1995) Les gaines des nerfs cranien dans la paroi laterale de la loge parasellaire (French). Neurochirurgie 41:403–412

    CAS  PubMed  Google Scholar 

  23. Davidson H, Ouchi T, Steiner RE (1985) MR imaging of congenital intracranial germinal layer neoplams. Neuroradiology 27:301–303

    CAS  PubMed  Google Scholar 

  24. Fournier D, Mercier P, Menei P, Pouplard F, Rizk T, Guy G (1992) Recurrent intrinsic brainstem epidermoid cyst. Childs Nerv Syst 8:471–474

    CAS  PubMed  Google Scholar 

  25. Ogawa T, Sekino H, Fuse T, Nakamura N (1985) Multiple intracranial epidermoids located in the brainstem and the middle cranial fossa: case report. Neurol Med Chir (Abstract) (Tokyo) 25:393–397

    Google Scholar 

  26. Yamakawa K, Shitara N, Genka S, Manaka S, Takakura K (1989) Clinical course and surgical prognosis of 33 cases of intracranial epidermoid tumors. Neurosurgery 24:568–573

    CAS  PubMed  Google Scholar 

  27. Wei R, Cai J, Wang H, Tao X, Zhu H, Zhou H (1999) Analysis of MRI and CT manifestations of paranasal sinuses and orbitocranial disorders with secondary exophthalmos (Abstract) (Chinese). Zhonghua Yan Ke Za Zhi 35:200–202

    CAS  PubMed  Google Scholar 

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Correspondence to Gökhan Akdemir.

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Akdemir, G., Dağlıoğlu, E. & Ergüngör, M.F. Dermoid lesion of the cavernous sinus: case report and review of the literature. Neurosurg Rev 27, 294–298 (2004).

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